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Chunlan Xu
Life Science
Northwestern Polytechnical University
Shaanxi
Language: Chinese, English
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Intestinal Health Nutrition Regulation Microecologics Development Application Intestinal Barrier Dysfunction High Altitude Hypoxia
Areas of Focus
  • Intestinal health and nutritional regulation
  • Development and application of new multifunctional complex microecologics
  • Intestinal barrier dysfunction and nutritional regulation under high altitude hypoxia environment
Work Experience
  • 2008-2010 Postdoctor, School of Life Sciences, Northwestern Polytechnical University
  • 2010-2011 Lecturer, School of Life Sciences, Northwestern Polytechnical University
  • 2011- Associate Professor, Doctor's Supervisor, School of Life Sciences, Northwestern Polytechnical University
  • 2014-2015 Visiting Scholar, University of California, Los Angeles
Academic Background & Achievements
  • 1998-2002 Bachelor: Huazhong Agricultural University
  • 2003-2008 Master-PhD: Zhejiang University
Publications
  • Proteective effects of selenium nanoparticle-enriched Lactococcus lactis NZ9000 against Enterotoxigenic Escherichia coli K88-induced intestinal barrier damage in mice, Chunlan Xu*, 2021
  • The role of vasoactive intestinal peptide and mast cells in the regulatory effect of Lactobacillus casei ATCC 393 on intestinal mucosal immune barrier, Chunlan Xu*, 2021
  • Biogenic selenium nanoparticles by Lactobacillus casei ATCC 393 alleviate diquat-induced intestinal barrier dysfunction in C57BL/6 mice through their antioxidant activity, Chunlan Xu*, 2020
  • Lactobacillus casei ATCC 393 alleviates Enterotoxigenic Escherichia coli K88-induced intestinal barrier dysfunction via TLRs/mast cells pathway, Chunlan Xu*, 2020
  • Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate intestinal epithelial barrier dysfunction caused by oxidative stress via Nrf2 signaling-mediated mitochondrial pathway, Chunlan Xu*, 2019
  • Biosynthesis of polysaccharides-capped selenium nanoparticles using Lactococcus lactis NZ9000 and their antioxidant and anti-inflammatory activities, Chunlan Xu*, 2019
  • Response of intestinal metabolome to polysaccharides from mycelia of Ganoderma lucidum, Chunlan Xu*, 2019
  • Preparation, characteristics and antioxidant activity of polysaccharides and proteins-capped selenium nanoparticles synthesized by Lactobacillus casei ATCC 393, Chunlan Xu*, 2018
  • Biogenic synthesis of novel functionalized selenium nanoparticles by Lactobacillus casei ATCC 393 and its protective effects on intestinal barrier dysfunction caused by Enterotoxigenic Escherichia coli K88, Chunlan Xu*, 2018
  • Recombinant vasoactive intestinal peptide analogue ameliorates TNBS-induced colitis in rats, Chunlan Xu*, 2018
  • Design, recombinant fusion expression and biological evaluation of vasoactive intestinal peptide analogue as novel antimicrobial agent, Chunlan Xu*, 2017
  • CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway, Chunlan Xu*, 2017
  • Resveratrol ameliorates chronic high altitude exposure-induced oxidative stress and lipid metabolism alteration in rats, Chunlan Xu*, 2016
  • Modulatory effects of vasoactive intestinal peptide on intestinal mucosal immunity and microbial community of weaned piglets challenged by an Enterotoxigenic Escherichia coli (K88), Chunlan Xu*, 2014
  • Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment, Chunlan Xu*, 2014
  • Effect of vitamin E supplementation on intestinal barrier function in rats exposed to high altitude hypoxia environment, Chunlan Xu*, 2014
  • Effect of iron glycinate chelate on the expression of hypoxia-inducible factor and antioxidant status in rats exposed to high altitude hypoxia environment, Chunlan Xu*, 2014
  • Effects of supplementing diets with Atractylodes macrocephala Koidz rhizomes on growth performance and immune function in piglets, Chunlan Xu*, 2012
  • Ceragenin CSA13 reduces Clostridium difficile infection in mice by modulating the intestinal microbiome and metabolites, Chunlan Xu*, 2018
  • Probiotic Saccharomyces boulardii CNCM I-745 prevents outbreak-associated Clostridium difficile-associated cecal inflammation in hamsters, Chunlan Xu*, 2016
Awards
  • 2011-2012 Undergraduate Scholarship of Northwestern Polytechnical University
  • 2011-2012 Outstanding Young Teacher of Northwestern Polytechnical University
  • 2013 Wu Yajun, Outstanding Young Teacher of Northwestern Polytechnical University (The first prize)
  • 2013 Excellent Class Teacher of Northwestern Polytechnical University
  • 2015-2016 Advanced Female Faculty and Staff member, 'March Eighth Flag-Bearer' of Northwestern Polytechnical University
  • 2019 Science and Technology Progress Award of Shaanxi Province (Second prize, ranking the 2nd)
  • 2020 Excellent Tutor of Mass Entrepreneurship and Innovation of Northwestern Polytechnical University
  • 2020 Outstanding Teacher of 'Curriculum Ideology and Politics' of Northwestern Polytechnical University
  • 2021 'Curriculum Ideology and Politics' First Prize of Northwestern Polytechnical University
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