2010-2015 PhD in Fermentation Engineering, Jiangnan University
Received National Natural Science Foundation of China Young Scientist Fund
Participated in national key research program on synthetic biology
2018.10-: Associate Researcher, School of Life Sciences, East China Normal University, Team of Haifeng Ye
2016.03-2018.01: Postdoctoral Researcher, Georgia Institute of Technology, Team of Rachel Chen
Research
Metabolic engineering and microbial synthetic biology for disease treatment Development and application of probiotic sensors Optogenetics Cancer immunotherapy
Microbial response to acid stress: mechanisms and applications, Ningzi Guan, Long Liu, 2020
Engineering a far-red light–activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors, Yuanhuan Yu, Xin Wu, Ningzi Guan, Jiawei Shao, Huiying Li, Yuxuan Chen, Yuan Ping, Dali Li, Haifeng Ye, 2020
A versatile genetic control system in mammalian cells and mice responsive to clinically licensed sodium ferulate, Yidan Wang, Shuyong Liao, Ningzi Guan, Yuanxiao Liu, Kaili Dong, Wilfried Weber, Haifeng Ye, 2020
Microbial production of nutraceuticals: challenges and prospects, Ningzi Guan, Jianghua Li, Guocheng Du, Jian Chen, Long Liu, 2019
A high-yielding enzymatic process for production of bioactive β-1,3-glucan oligosaccharides with defined size, Ningzi Guan, Juping Yu, Wei Liu, Rachel Chen, 2018
Comparative genomics and transcriptomics analysis-guided metabolic engineering of Propionibacterium acidipropionicifor improved propionic acid production, Ningzi Guan, Bin Du, Jianghua Li, Hyun-Dong Shin, Rachel Chen, Guocheng Du, Jian Chen, Long Liu, 2018
Recent technology development for the biosynthesis of Human Milk Oligosaccharide, Ningzi Guan, Rachel Chen, 2018
Microbial response to environmental stresses: from fundamental mechanisms to practical applications, Ningzi Guan, Jianghua Li, Hyun-Dong Shin, Guocheng Du, Jian Chen, Long Liu, 2017
A DNA bubble-mediated gene regulation system based on thrombin-bound DNA aptamers, Jing Wang, Le Yang, Xun Cui, Zhe Zhang, Lichun Dong, Ningzi Guan, 2017
A real-time control system of gene expression using ligand-bound nucleic acid aptamer for metabolic engineering, Jing Wang, Xun Cui, Le Yang, Zhe Zhang, Liping Lv, Haoyuan Wang, Zhenmin Zhao, Ningzi Guan, Lichun Dong, Rachel Chen, 2017
Development of GRAS strains for nutraceutical production using systems and synthetic biology approaches: Advances and prospects, Long Liu, Ningzi Guan, Jianghua Li, Guocheng Du, Jian Chen, 2017
Metabolic engineering of acid resistance elements to improve acid resistance and propionic acid production of Propionibacterium jensenii, Ningzi Guan, Jianghua Li, Hyun-Dong Shin, Guocheng Du, Jian Chen, Long Liu, 2016
Pathway engineering of Propionibacterium jensenii for improved production of propionic acid, Long Liu, Ningzi Guan, Gexin Zhu, Jianghua Li, Hyun-Dong Shin, Guocheng Du, Jian Chen, 2016
Comparative metabolomics analysis of the key metabolic nodes in propionic acid synthesis in Propionibacterium acidipropionici, Ningzi Guan, Gexin Zhu, Jianghua Li, Hyun-Dong Shin, Jing Wu, Zhongping Shi, Long Liu, 2015
Engineering propionibacteria as versatile cell factories for the production of industrially important chemicals: advances, challenges, and prospects, Ningzi Guan, Gexin Zhu, Jianghua Li, Hyun-Dong Shin, Jing Wu, Zhongping Shi, Long Liu, 2015
Understanding of how Propionibacterium acidipropionici respond to propionic acid stress at the level of proteomics, Ningzi Guan, Long Liu, Hyun-Dong Shin, Rachel Chen, Juan Zhang, Jianghua Li, Guocheng Du, Zhongping Shi, Jian Chen, 2014
Systems-level understanding how Propionibacterium acidipropionici respond to propionic acid stress at the microenvironment levels: Mechanism and application, Ningzi Guan, Long Liu, Hyun-Dong Shin, Rachel Chen, Juan Zhang, Jianghua Li, Guocheng Du, Zhongping Shi, Jian Chen, 2013
Genome shuffling improves acid tolerance of Propionibacterium acidipropionici and propionic acid production, Ningzi Guan, Long Liu, Gexin Zhu, Qiaoyan Xu, Jianghua Li, Guocheng Du, Jian Chen, 2012
