Areas of Focus
- 代谢工程与微生物合成生物学在疾病治疗中的应用研究
- 益生菌传感器的开发与应用
- 光遗传学
- 肿瘤免疫治疗
Work Experience
- 2018.10-: 副研究员，生命科学学院，华东师范大学，叶海峰团队
- 2016.03-2018.01: 博士后，佐治亚理工学院，Rachel Chen 团队
Academic Background & Achievements
- 2010-2015 博士，发酵工程，江南大学
- 获得国家自然科学基金青年基金
- 参与国家重点研究计划合成生物学专项
Publications
- Microbial response to acid stress: mechanisms and applications, 管宁子, 刘龙, 2020
- Engineering a far-red light–activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors, 于元欢, 吴欣, 管宁子, 邵佳伟, 李慧英, 陈宇轩, 平远, 李大力, 叶海峰, 2020
- A versatile genetic control system in mammalian cells and mice responsive to clinically licensed sodium ferulate, 王一丹, 廖书勇, 管宁子, 刘远晓, 董凯丽, Wilfried Weber, 叶海峰, 2020
- Microbial production of nutraceuticals: challenges and prospects, 管宁子, 李江华, 堵国成, 陈坚, 刘龙, 2019
- TCA-Cycle powered synthesis of fucosylated oligosaccharides, 管宁子, Hyun-Dong Shin, 龙凌风, Parastoo Azadi, Rachel Chen, 2018
- A high-yielding enzymatic process for production of bioactive β-1,3-glucan oligosaccharides with defined size, 管宁子, 于菊萍, 刘伟, Rachel Chen, 2018
- Comparative genomics and transcriptomics analysis-guided metabolic engineering of Propionibacterium acidipropionicifor improved propionic acid production, 管宁子, 杜斌, 李江华, Hyun-Dong Shin, Rachel Chen, 堵国成, 陈坚, 刘龙, 2018
- Recent technology development for the biosynthesis of Human Milk Oligosaccharide, 管宁子, Rachel Chen, 2018
- Microbial response to environmental stresses: from fundamental mechanisms to practical applications, 管宁子, 李江华, Hyun-Dong Shin, 堵国成, 陈坚, 刘龙, 2017
- A DNA bubble-mediated gene regulation system based on thrombin-bound DNA aptamers, 王静, 杨乐, 崔迅, 张哲, 董立春, 管宁子, 2017
- A real-time control system of gene expression using ligand-bound nucleic acid aptamer for metabolic engineering, 王静, 崔迅, 杨乐, 张哲, 吕丽萍, 王浩远, 赵振民, 管宁子, 董立春, Rachel Chen, 2017
- Development of GRAS strains for nutraceutical production using systems and synthetic biology approaches: Advances and prospects, 刘龙, 管宁子, 李江华, 堵国成, 陈坚, 2017
- Metabolic engineering of acid resistance elements to improve acid resistance and propionic acid production of Propionibacterium jensenii, 管宁子, 李江华, Hyun-Dong Shin, 堵国成, 陈坚, 刘龙, 2016
- Pathway engineering of Propionibacterium jensenii for improved production of propionic acid, 刘龙, 管宁子, 朱格新, 李江华, Hyun-Dong Shin, 堵国成, 陈坚, 2016
- Comparative metabolomics analysis of the key metabolic nodes in propionic acid synthesis in Propionibacterium acidipropionici, 管宁子, 朱格新, 李江华, Hyun-Dong Shin, 吴静, 石中平, 刘龙, 2015
- Engineering propionibacteria as versatile cell factories for the production of industrially important chemicals: advances, challenges, and prospects, 管宁子, 朱格新, 李江华, Hyun-Dong Shin, 吴静, 石中平, 刘龙, 2015
- Understanding of how Propionibacterium acidipropionici respond to propionic acid stress at the level of proteomics, 管宁子, 刘龙, Hyun-Dong Shin, Rachel Chen, 张娟, 李江华, 堵国成, 石中平, 陈坚, 2014
- Systems-level understanding how Propionibacterium acidipropionici respond to propionic acid stress at the microenvironment levels: Mechanism and application, 管宁子, 刘龙, Hyun-Dong Shin, Rachel Chen, 张娟, 李江华, 堵国成, 石中平, 陈坚, 2013
- Genome shuffling improves acid tolerance of Propionibacterium acidipropionici and propionic acid production, 管宁子, 刘龙, 朱格新, 徐
