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Lei Li
Life Science
East China Normal University
Shanghai
Language: Chinese, English
Proteolytic Pathways
Ubiquitin-Independent
Disease Regulation
Aging
Tumors
Drug Target Discovery
Bone Diseases
Regulatory Mechanisms
Protein Degradation
Molecular Biology
Areas of Focus
- Ubiquitin-independent proteolytic pathways in disease regulation (aging, tumors)
- Drug target discovery and regulatory mechanisms in bone diseases
Work Experience
- 2015/09 - Present, East China Normal University, School of Life Sciences
Academic Background & Achievements
- PhD: East China Normal University, 2013
- Postdoctoral Research: Second Military Medical University, 2013-2015
Publications
- REGγ-activated 20S proteasome degradation of substrate proteins like CK1δ, GSK3β, CK1ε, Lats1, and Smad7, Lei Li, 2013
- REGγ promotes skin cancer, colon cancer, and thyroid cancer development, Lei Li, 2015
- Phosphorylation modification of NIP30 as a molecular switch for REGγ-20S proteasome function, Lei Li, 2020
Awards
- Shanghai Youth Science and Technology Star, 2016
- Shanghai Biochemical Association Academic Newcomer Second Prize, 2015
