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Lei Li
lli@bio.ecnu.edu.cn
Chinese, English
Shanghai
East China Normal University
Life Sciences
  • PhD: East China Normal University, 2013
  • Postdoctoral Research: Second Military Medical University, 2013-2015
  • 2015/09 - Present, East China Normal University, School of Life Sciences
  • Shanghai Youth Science and Technology Star, 2016
  • Shanghai Biochemical Association Academic Newcomer Second Prize, 2015
Ubiquitin-independent proteolytic pathways in disease regulation (aging, tumors)
Drug target discovery and regulatory mechanisms in bone diseases
  • REGγ-activated 20S proteasome degradation of substrate proteins like CK1δ, GSK3β, CK1ε, Lats1, and Smad7, Lei Li, 2013
  • REGγ promotes skin cancer, colon cancer, and thyroid cancer development, Lei Li, 2015
  • Phosphorylation modification of NIP30 as a molecular switch for REGγ-20S proteasome function, Lei Li, 2020
Proteolytic Pathways Ubiquitin-Independent Disease Regulation Aging Tumors Drug Target Discovery Bone Diseases Regulatory Mechanisms Protein Degradation Molecular Biology

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