Professor | Zhiyong Mao | Asia Growth Partners

Name	Zhiyong Mao
Contact Information	zhiyong_mao@tongji.edu.cn
Language ability	English, Chinese
Province	Shanghai

Name

Zhiyong Mao

Contact Information

zhiyong_mao@tongji.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2002 - Bachelor's Degree: Nanjing University, School of Life Sciences 2004 - Master's Degree: Nanjing University, School of Life Sciences 2010 - PhD: University of Rochester, USA National Outstanding Young Scientist, Overseas High-level Youth Talent
Work Experience	2010-2012 - University of Rochester, Department of Biology: Postdoctoral Researcher Since 2012 - Tongji University: Head of Research Group on Aging, Stem Cells, and Gynecological Tumor Related Genomic Stability
Awards	2013 - Chief Scientist of the National '973' Young Project 2013 - Shanghai 'Pujiang Talent' Program 2016 - National Natural Science Foundation of China Outstanding Young Scientist Fund 2019 - Shanghai 'Outstanding Academic Leader' Project and 'Dawn Program' 2021 - Third Prize of Shanghai Medical Science and Technology Award (First Accomplisher) 2022 - National Outstanding Young Scientist Fund

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2002 - Bachelor's Degree: Nanjing University, School of Life Sciences
2004 - Master's Degree: Nanjing University, School of Life Sciences
2010 - PhD: University of Rochester, USA
National Outstanding Young Scientist, Overseas High-level Youth Talent

Work Experience

2010-2012 - University of Rochester, Department of Biology: Postdoctoral Researcher
Since 2012 - Tongji University: Head of Research Group on Aging, Stem Cells, and Gynecological Tumor Related Genomic Stability

Awards

2013 - Chief Scientist of the National '973' Young Project
2013 - Shanghai 'Pujiang Talent' Program
2016 - National Natural Science Foundation of China Outstanding Young Scientist Fund
2019 - Shanghai 'Outstanding Academic Leader' Project and 'Dawn Program'
2021 - Third Prize of Shanghai Medical Science and Technology Award (First Accomplisher)
2022 - National Outstanding Young Scientist Fund

Areas of Focus	Aging and related diseases Stem cell genomic stability Development and translation of new methods for delaying aging and treating related diseases
Publications	Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation, Zhen Z, Chen Y, Wang H, Tang H, Zhang H, Liu H, Jiang Y, Mao Z, 2023 Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription, Chen Y, Zhen Z, Chen L, Wang H, Wang X, Sun X, Song Z, Wang H, Lin Y, Zhang W, Wu G, Jiang Y, Mao Z, 2023 Impaired end joining induces cardiac atrophy in a Hutchinson–Gilford progeria mouse model, Chen Y, Huang S, Cui Z, Sun X, Tang Y, Zhang H, Chen Z, Jiang R, Zhang W, Li X, Chen J, Liu B, Jiang Y, Wei K, Mao Z, 2023 Loss of ER/PR/HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer, Sun X, Tang H, Chen Y, Chen Z, Hu Z, Cui Z, Tao Y, Yuan J, Fu Y, Zhuang Z, He Q, Li Q, Xu X, Wan X, Jiang Y, Mao Z, 2023 Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer, Zhang W, Wang M, Song Z, Fu Q, Chen J, Zhang W, Gao S, Sun X, Yang G, Zhang Q, Yang J, Tang H, Wang H, Kou X, Wang H, Mao Z, Xu X, Gao S, Jiang Y*, 2023

Areas of Focus

Aging and related diseases
Stem cell genomic stability
Development and translation of new methods for delaying aging and treating related diseases

Publications

Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation, Zhen Z, Chen Y, Wang H, Tang H, Zhang H, Liu H, Jiang Y, Mao Z*, 2023
Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription, Chen Y, Zhen Z, Chen L, Wang H, Wang X, Sun X, Song Z, Wang H, Lin Y, Zhang W, Wu G, Jiang Y*, Mao Z*, 2023
Impaired end joining induces cardiac atrophy in a Hutchinson–Gilford progeria mouse model, Chen Y, Huang S, Cui Z, Sun X, Tang Y, Zhang H, Chen Z, Jiang R, Zhang W, Li X, Chen J, Liu B, Jiang Y, Wei K*, Mao Z*, 2023
Loss of ER/PR/HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer, Sun X, Tang H, Chen Y, Chen Z, Hu Z, Cui Z, Tao Y, Yuan J, Fu Y, Zhuang Z, He Q, Li Q, Xu X, Wan X, Jiang Y*, Mao Z*, 2023
Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer, Zhang W, Wang M, Song Z, Fu Q, Chen J, Zhang W, Gao S, Sun X, Yang G, Zhang Q, Yang J, Tang H, Wang H, Kou X, Wang H, Mao Z*, Xu X*, Gao S*, Jiang Y*, 2023

Aging Disease Development Dna Repair Regulatory Mechanisms Stem Cells Genomic Stability Gynecological Tumors Method Development Disease Prevention Translational Research

Han Song Deng - Tongji University

Fanglin Sun - Tongji University

Yu Chen - Tongji University

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