Professor | Xu Lingyan | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Xu Lingyan
Contact Information	lyxu@bio.ecnu.edu.cn
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Xu Lingyan

Contact Information

lyxu@bio.ecnu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	East China Normal University
Faculty	Life Sciences
Academic Background & Achievements	2005-2010 Ph.D. in Biochemistry and Molecular Biology/Endocrine Metabolic Diseases, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Supervisor: Ning Guang (Academician of the Chinese Academy of Engineering)
Work Experience	2017-present Researcher, Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University 2011-2016 Postdoctoral Fellow (Visiting Fellow), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, USA 2010-2011 Assistant Researcher, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Awards	Selected for the National Natural Science Foundation of China 'Outstanding Youth', Shanghai 'Pujiang Talent Plan', East China Normal University 'Zijiang Outstanding Young Scholar'

University/Lab Affiliation and Title

East China Normal University

Faculty

Life Sciences

Academic Background & Achievements

2005-2010 Ph.D. in Biochemistry and Molecular Biology/Endocrine Metabolic Diseases, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Supervisor: Ning Guang (Academician of the Chinese Academy of Engineering)

Work Experience

2017-present Researcher, Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University
2011-2016 Postdoctoral Fellow (Visiting Fellow), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, USA
2010-2011 Assistant Researcher, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences

Awards

Selected for the National Natural Science Foundation of China 'Outstanding Youth', Shanghai 'Pujiang Talent Plan', East China Normal University 'Zijiang Outstanding Young Scholar'

Areas of Focus	Aging Biology Brown Fat Function Decline in Aging Systemic Lipid Metabolism Disorders
Publications	Local Hyperthermia Therapy Induces Browning of White Fat and Treats Obesity, Li Y, Wang D, Ping X, Zhang Y, Zhang T, Wang L, Jin L, Zhao W, Guo M, Shen F, Meng M, Chen X, Zheng Y, Wang J, Li D, Zhang Q, Hu C, Xu L, Ma X, 2022 AAV-Mediated Nuclear Localized PGC1α4 Delivery in Muscle Ameliorates Sarcopenia and Aging-associated Metabolic Dysfunctions, Guo M, Zhang J, Ma Y, Zhu Z, Zuo H, Yao J, Wu X, Wang D, Yu J, Meng M, Liu C, Zhang Y, Chen J, Lu J, Ding S, Hu C, Ma X, Xu L, 2023 Fibroblast growth factor 6 promotes adipocyte progenitor cell proliferation for adipose tissue homeostasis, Liu C, Meng M, Xu B, Xu Y, Li G, Cao Y, Wang D, Qiu J, Yu J, Xu L, Ma X, Hu C, 2023 Irisin ameliorates age-associated sarcopenia and metabolic dysfunction, Guo M, Yao J, Li J, Zhang J, Wang D, Zuo H, Zhang Y, Xu B, Zhong Y, Shen F, Lu J, Ding S, Hu C, Xu L, Xiao J, Ma X, 2023 A fluorinated peptide with high serum- and lipid-tolerence for the delivery of siRNA drugs to treat obesity and metabolic dysfunction, Qiu J, Fan Q, Xu S, Wang D, Chen J, Wang S, Hu T, Ma X, Cheng Y, Xu L, 2022 Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents, Yu J, Chen X, Zhang Y, Cui X, Zhang Z, Guo W, Wang D, Huang S, Chen Y, Hu Y, Zhao C, Qiu J, Li Y, Meng M, Guo M, Shen F, Zhang M, Zhou B, Gu X, Wang J, Wang X, Ma X, Xu L, 2022 FOXA3 induction under endoplasmic reticulum stress contributes to non-alcoholic fatty liver disease, Liu C, Zhou B, Meng M, Zhao W, Wang D, Yuan Y, Zheng Y, Qiu J, Li Y, Li G, Xiong X, Bian H, Zhang H, Wang H, Ma X, Hu C, Xu L, Lu Y, 2021 PPARγ agonists delay age-associated metabolic disease and extend longevity, Xu L, Ma X, Verma N, Perie L, Pendse J, Shamloo S, Marie Josephson A, Wang D, Qiu J, Guo M, Ping X, Allen M, Noguchi A, Springer D, Shen F, Liu C, Zhang S, Li L, Li J, Xiao J, Lu J, Du Z, Luo J, Aleman JO, Leucht P, Mueller E, 2020 C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake, Wang D, Cheng X, Li Y, Guo M, Zhao W, Qiu J, Zheng Y, Meng M, Ping X, Chen X, Wang S, Luo J, Luo Q, Ma X, Xu L, 2020 Ablation of PPARγ in subcutaneous fat exacerbates age-associated obesity and metabolic decline, Xu L, Ma X, Verma NK, Wang D, Gavrilova O, Proia RL, Finkel T, Mueller E, 2018

Areas of Focus

Aging Biology
Brown Fat Function Decline in Aging
Systemic Lipid Metabolism Disorders

Publications

Local Hyperthermia Therapy Induces Browning of White Fat and Treats Obesity, Li Y, Wang D, Ping X, Zhang Y, Zhang T, Wang L, Jin L, Zhao W, Guo M, Shen F, Meng M, Chen X, Zheng Y, Wang J, Li D, Zhang Q, Hu C, Xu L, Ma X, 2022
AAV-Mediated Nuclear Localized PGC1α4 Delivery in Muscle Ameliorates Sarcopenia and Aging-associated Metabolic Dysfunctions, Guo M, Zhang J, Ma Y, Zhu Z, Zuo H, Yao J, Wu X, Wang D, Yu J, Meng M, Liu C, Zhang Y, Chen J, Lu J, Ding S, Hu C, Ma X, Xu L, 2023
Fibroblast growth factor 6 promotes adipocyte progenitor cell proliferation for adipose tissue homeostasis, Liu C, Meng M, Xu B, Xu Y, Li G, Cao Y, Wang D, Qiu J, Yu J, Xu L, Ma X, Hu C, 2023
Irisin ameliorates age-associated sarcopenia and metabolic dysfunction, Guo M, Yao J, Li J, Zhang J, Wang D, Zuo H, Zhang Y, Xu B, Zhong Y, Shen F, Lu J, Ding S, Hu C, Xu L, Xiao J, Ma X, 2023
A fluorinated peptide with high serum- and lipid-tolerence for the delivery of siRNA drugs to treat obesity and metabolic dysfunction, Qiu J, Fan Q, Xu S, Wang D, Chen J, Wang S, Hu T, Ma X, Cheng Y, Xu L, 2022
Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents, Yu J, Chen X, Zhang Y, Cui X, Zhang Z, Guo W, Wang D, Huang S, Chen Y, Hu Y, Zhao C, Qiu J, Li Y, Meng M, Guo M, Shen F, Zhang M, Zhou B, Gu X, Wang J, Wang X, Ma X, Xu L, 2022
FOXA3 induction under endoplasmic reticulum stress contributes to non-alcoholic fatty liver disease, Liu C, Zhou B, Meng M, Zhao W, Wang D, Yuan Y, Zheng Y, Qiu J, Li Y, Li G, Xiong X, Bian H, Zhang H, Wang H, Ma X, Hu C, Xu L, Lu Y, 2021
PPARγ agonists delay age-associated metabolic disease and extend longevity, Xu L, Ma X, Verma N, Perie L, Pendse J, Shamloo S, Marie Josephson A, Wang D, Qiu J, Guo M, Ping X, Allen M, Noguchi A, Springer D, Shen F, Liu C, Zhang S, Li L, Li J, Xiao J, Lu J, Du Z, Luo J, Aleman JO, Leucht P, Mueller E, 2020
C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake, Wang D, Cheng X, Li Y, Guo M, Zhao W, Qiu J, Zheng Y, Meng M, Ping X, Chen X, Wang S, Luo J, Luo Q, Ma X, Xu L, 2020
Ablation of PPARγ in subcutaneous fat exacerbates age-associated obesity and metabolic decline, Xu L, Ma X, Verma NK, Wang D, Gavrilova O, Proia RL, Finkel T, Mueller E, 2018

Aging Biology Brown Fat Decline Function Systemic Lipid Metabolism Disorder Molecular Mechanisms

Le Rongrong - Tongji University

Changdong Lin - Tongji University

Fanglin Sun - Tongji University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us