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Huaqing Chen
Life Science
East China Normal University
Shanghai
Language: English, Chinese
Immunology
Inflammation
Metabolism
Disease Models
Cell Signaling
Therapeutic Targets
Immune System
Pathogenesis
Molecular Biology
Biochemistry
Areas of Focus
- Immunology
- Inflammation and Metabolism
- Disease Models
Work Experience
- 2007 - Present, East China Normal University, Institute of Biomedical Sciences, Senior Engineer
- 1998 - 2006, Shanghai Industrial Kehua Biotechnology Co., Ltd., R&D Department Director, Senior Engineer
- 1994 - 1997, GlaxoWellcome UK Research Centre, Cell Biology, Visiting Scholar
- 1993 - 1994, Wellcome Research Laboratories UK, Visiting Scholar
- 1989 - 1992, Shanghai Institute of Biological Products, Immunology Research Laboratory, Assistant Researcher
Academic Background & Achievements
- 1994/7 - 1997/11, PhD in Immunology, King's College London
- 1986/9 - 1989/8, Master in Immunology, Shanghai Second Medical University
- 1982/9 - 1986/8, Bachelor in Microbiology, Fudan University
Publications
- Therapeutic potentiation of the immune system by costimulatory Schiff base-forming drugs, Huaqing Chen, 1995
- Schiff base forming drugs: mechanisms of immune potentiation and therapeutic potential, Huaqing Chen, 1996
- Convergence of Schiff base costimulatory signalling and T-cell receptor signalling at the level of MAP kinase ERK2, Huaqing Chen, 1997
- Potentiation of the immune system by Schiff base-forming drugs: Mechanism of action and therapeutic potential, Huaqing Chen, 1997
- 席夫碱和免疫增强剂：作用机理及应用潜力, Huaqing Chen, 1998
- 离子转运抑制剂对席夫碱增强免疫效应的影响, Huaqing Chen, 2000
- 抗HBeAg不同位点的单克隆抗体杂交瘤细胞株的制备及其应用, Huaqing Chen, 2006
- G蛋白偶联受体及其信号传导在免疫与炎症中的作用, Huaqing Chen, 2009
- Amelioration of Experimental Autoimmune Encephalomyelitis by Plumbagin through Down-Regulation of JAK-STAT and NF-κB Signaling Pathways, Huaqing Chen, 2011
- 丁酸钠及其G蛋白偶联受体对T淋巴细胞的调节作用, Huaqing Chen, 2012
- A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-cells in Type 2 Diabetic Mice, Huaqing Chen, 2015
- PubAngioGen: a database and knowledge for angiogenesis and related diseases, Huaqing Chen, 2015
- Lage genomic fragment deletion and functional cassette knock in via Cas9 protein mediated genome editing in one cell embryos, Huaqing Chen, 2015
- LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption, Huaqing Chen, 2016
- Effects of Melanocortin 3 and 4 receptor deficiency on energy homostasis in rats, Huaqing Chen, 2016
- A Betulinic acid derivative SH479 inhibits collagen-induced arthritis by modulating T cell differentiation and cytokine balance, Huaqing Chen, 2017
- SH479, a betulinic acid derivative, ameliorates experimental autoimmune encephalomyelitis by regulating the Th17/Treg balance, Huaqing Chen, 2017
- Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress, Huaqing Chen, 2017
- Hyperlipidemia induces typical atherosclerosis development in Ldlr and Apoe deficient rats, Huaqing Chen, 2018
- Kisspeptin receptor GPR54 promotes adipocyte differentiation and fat accumulation in mice, Huaqing Chen, 2018
- GPR54 Deficiency Reduces the Treg Population and Aggravates Experimental Autoimmune Encephalomyelitis in Mice, Huaqing Chen, 2018
- Novel Rat Models for Atherosclerosis, Huaqing Chen, 2018
- The G2A receptor deficiency aggravates atherosclerosis in rats by regulating macrophages and lipid metabolism, Huaqing Chen, 2021
