Professor | 陈华青 | 数字化转型顾问

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Name	陈华青
Contact Information	hqchen@bio.ecnu.edu.cn
Language ability	英语, 汉语
Province	上海

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Name

陈华青

Contact Information

hqchen@bio.ecnu.edu.cn

Language ability

英语, 汉语

Province

上海

University/Lab Affiliation and Title	华东师范大学
Faculty	Life Sciences
Academic Background & Achievements	1994/7 - 1997/11，伦敦大学King's College London，免疫学，博士 1986/9 - 1989/8，上海第二医科大学，免疫学，硕士 1982/9 - 1986/8，复旦大学，微生物学，学士
Work Experience	2007 - 至今，华东师范大学，生命科学学院生命医学研究所，高级工程师 1998 - 2006，上海实业科华生物技术有限公司研发部主任，高级工程师 1994 - 1997，GlaxoWellcome英国研究中心，细胞生物学，访问学者 1993 - 1994，英国Wellcome Research Laboratories，访问学者 1989 - 1992，卫生部上海生物制品研究所免疫学研究室，助理研究员

University/Lab Affiliation and Title

华东师范大学

Faculty

Life Sciences

Academic Background & Achievements

1994/7 - 1997/11，伦敦大学King's College London，免疫学，博士
1986/9 - 1989/8，上海第二医科大学，免疫学，硕士
1982/9 - 1986/8，复旦大学，微生物学，学士

Work Experience

2007 - 至今，华东师范大学，生命科学学院生命医学研究所，高级工程师
1998 - 2006，上海实业科华生物技术有限公司研发部主任，高级工程师
1994 - 1997，GlaxoWellcome英国研究中心，细胞生物学，访问学者
1993 - 1994，英国Wellcome Research Laboratories，访问学者
1989 - 1992，卫生部上海生物制品研究所免疫学研究室，助理研究员

Areas of Focus	免疫学炎症与代谢疾病模型
Publications	Therapeutic potentiation of the immune system by costimulatory Schiff base-forming drugs, 陈华青, 1995 Schiff base forming drugs: mechanisms of immune potentiation and therapeutic potential, 陈华青, 1996 Convergence of Schiff base costimulatory signalling and T-cell receptor signalling at the level of MAP kinase ERK2, 陈华青, 1997 Potentiation of the immune system by Schiff base-forming drugs: Mechanism of action and therapeutic potential, 陈华青, 1997 席夫碱和免疫增强剂：作用机理及应用潜力, 陈华青, 1998 离子转运抑制剂对席夫碱增强免疫效应的影响, 陈华青, 2000 抗HBeAg不同位点的单克隆抗体杂交瘤细胞株的制备及其应用, 陈华青, 2006 G蛋白偶联受体及其信号传导在免疫与炎症中的作用, 陈华青, 2009 Amelioration of Experimental Autoimmune Encephalomyelitis by Plumbagin through Down-Regulation of JAK-STAT and NF-κB Signaling Pathways, 陈华青, 2011 丁酸钠及其G蛋白偶联受体对T淋巴细胞的调节作用, 陈华青, 2012 A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-cells in Type 2 Diabetic Mice, 陈华青, 2015 PubAngioGen: a database and knowledge for angiogenesis and related diseases, 陈华青, 2015 Lage genomic fragment deletion and functional cassette knock in via Cas9 protein mediated genome editing in one cell embryos, 陈华青, 2015 LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption, 陈华青, 2016 Effects of Melanocortin 3 and 4 receptor deficiency on energy homostasis in rats, 陈华青, 2016 A Betulinic acid derivative SH479 inhibits collagen-induced arthritis by modulating T cell differentiation and cytokine balance, 陈华青, 2017 SH479, a betulinic acid derivative, ameliorates experimental autoimmune encephalomyelitis by regulating the Th17/Treg balance, 陈华青, 2017 Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress, 陈华青, 2017 Hyperlipidemia induces typical atherosclerosis development in Ldlr and Apoe deficient rats, 陈华青, 2018 Kisspeptin receptor GPR54 promotes adipocyte differentiation and fat accumulation in mice, 陈华青, 2018 GPR54 Deficiency Reduces the Treg Population and Aggravates Experimental Autoimmune Encephalomyelitis in Mice, 陈华青, 2018 Novel Rat Models for Atherosclerosis, 陈华青, 2018 The G2A receptor deficiency aggravates atherosclerosis in rats by regulating macrophages and lipid metabolism, 陈华青, 2021

Areas of Focus

免疫学
炎症与代谢
疾病模型

Publications

Therapeutic potentiation of the immune system by costimulatory Schiff base-forming drugs, 陈华青, 1995
Schiff base forming drugs: mechanisms of immune potentiation and therapeutic potential, 陈华青, 1996
Convergence of Schiff base costimulatory signalling and T-cell receptor signalling at the level of MAP kinase ERK2, 陈华青, 1997
Potentiation of the immune system by Schiff base-forming drugs: Mechanism of action and therapeutic potential, 陈华青, 1997
席夫碱和免疫增强剂：作用机理及应用潜力, 陈华青, 1998
离子转运抑制剂对席夫碱增强免疫效应的影响, 陈华青, 2000
抗HBeAg不同位点的单克隆抗体杂交瘤细胞株的制备及其应用, 陈华青, 2006
G蛋白偶联受体及其信号传导在免疫与炎症中的作用, 陈华青, 2009
Amelioration of Experimental Autoimmune Encephalomyelitis by Plumbagin through Down-Regulation of JAK-STAT and NF-κB Signaling Pathways, 陈华青, 2011
丁酸钠及其G蛋白偶联受体对T淋巴细胞的调节作用, 陈华青, 2012
A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-cells in Type 2 Diabetic Mice, 陈华青, 2015
PubAngioGen: a database and knowledge for angiogenesis and related diseases, 陈华青, 2015
Lage genomic fragment deletion and functional cassette knock in via Cas9 protein mediated genome editing in one cell embryos, 陈华青, 2015
LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption, 陈华青, 2016
Effects of Melanocortin 3 and 4 receptor deficiency on energy homostasis in rats, 陈华青, 2016
A Betulinic acid derivative SH479 inhibits collagen-induced arthritis by modulating T cell differentiation and cytokine balance, 陈华青, 2017
SH479, a betulinic acid derivative, ameliorates experimental autoimmune encephalomyelitis by regulating the Th17/Treg balance, 陈华青, 2017
Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress, 陈华青, 2017
Hyperlipidemia induces typical atherosclerosis development in Ldlr and Apoe deficient rats, 陈华青, 2018
Kisspeptin receptor GPR54 promotes adipocyte differentiation and fat accumulation in mice, 陈华青, 2018
GPR54 Deficiency Reduces the Treg Population and Aggravates Experimental Autoimmune Encephalomyelitis in Mice, 陈华青, 2018
Novel Rat Models for Atherosclerosis, 陈华青, 2018
The G2A receptor deficiency aggravates atherosclerosis in rats by regulating macrophages and lipid metabolism, 陈华青, 2021

免疫学炎症代谢疾病模型细胞信号治疗靶点免疫系统发病机制分子生物学生物化学

陈坤 - 同济大学

徐艳萍 - 同济大学

俞芳 - 上海师范大学

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