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Ming Jiang
Life Science
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English
Biosynthesis
Natural Products
Polyketones
Nucleoside Antibiotics
Synthetic Biology
Biocatalysis
Structural Biology
Enzyme Engineering
Microbial Products
Biochemical Pathways
Areas of Focus
- Biosynthesis mechanisms of complex natural products
- Synthetic biology studies to enhance natural product yields
Work Experience
- 2013.06 - Present: Associate Researcher, School of Life Sciences, Shanghai Jiao Tong University
- 2011.09 - 2013.05: Postdoctoral Fellow, Chemical and Biological Engineering, State of New York University at Buffalo
- 2010.09 - 2011.08: Postdoctoral Fellow, Chemical Engineering, Tufts University
- 2008.09 - 2010.08: Research Assistant, Chemistry, Hong Kong University of Science and Technology
Academic Background & Achievements
- 2005-2008: PhD in Chemistry, Hong Kong University of Science and Technology
- 2001-2004: Master's in Biochemistry, Hong Kong University of Science and Technology
- 1997-2001: Bachelor's in Chemistry, Fudan University
Publications
- O-methyltransferase-like enzyme catalyzed diazo installation in polyketide biosynthesis, Zhao Y, Liu X, Xiao Z, Zhou J, Song X, Wang X, Hu L, Wang Y, Sun P, Wang W, He X, Lin S, Deng Z, Pan L, Jiang M, 2023
- Importance of aspartic acid side chain carboxylate-arginine interaction in substrate selection of arginine 2,3-aminomutase BlsG, Luo X, Wang X, Zhang L, Du A, Deng Z, Jiang M, He X, 2023
- Unexpected Role of a short-chain dehydrogenase/reductase family protein in type II polyketide biosynthesis, Gao Y, Zhao Y, Zhou J, Yang M, Lin L, Wang W, Tao M, Deng Z, Jiang M, 2022
- A [3Fe-4S] cluster and tRNA-dependent aminoacyltransferase BlsK in the biosynthesis of Blasticidin S, Wang X, Zhao Y, Gao Y, Luo X, Du A, Deng Z, Zabriskie TM, He X, Jiang M, 2021
- Challenges of functional expression of complex polyketide biosynthetic gene clusters, Gao Y, Zhao Y, He X, Deng Z, Jiang M, 2021
- Offloading role of a discrete thioesterase in type II polyketide biosynthesis, Hua K, Liu X, Zhao Y, Gao Y, Pan L, Zhang H, Deng Z, Jiang M, 2020
- Heterologous Biosynthesis of Type II Polyketide Products Using E. coli, Liu X, Hua K, Liu D, Wu ZL, Wang Y, Zhang H, Deng Z, Pfeifer BA, Jiang M, 2020
- Reconstitution of kinamycin biosynthesis within the heterologous host streptomyces albus J1074, Liu X, Liu D, Xu M, Tao M, Bai L, Deng Z, Pfeifer BA, Jiang M
- Formation of an angular aromatic polyketide from a linear anthrene precursor via oxidative rearrangement, Gao G, Liu X, Xu M, Wang Y, Zhang F, Xu L, Lv J, Long Q, Kang Q, Ou HY, Wang Y, Rohr J, Deng Z, Jiang M, Lin S, Tao M, 2017
- Engineering the shikimate pathway for biosynthesis of molecules with pharmaceutical activities in E. coli, Jiang M, Zhang H, 2016
