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Lu Qing
Life Science
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English
Protein Assembly
Protein Regulation
Protein Machines
Brain Development
Genetic Mechanisms
Cytoskeletal Dynamics
Protein Dynamics
Hereditary Deafness
Genetic Disorders
Cell Biology
Areas of Focus
- Assembly and regulation of protein machines
- Genetic mechanisms of cytoskeletal and cytoskeletal protein dynamics in brain development disorders
- Genes related to hereditary deafness
Work Experience
- 2017-present - Shanghai Jiao Tong University - Special Researcher, Research Group Leader, Doctoral Supervisor
Academic Background & Achievements
- 2005-2009 Bachelor: Nanjing University
- 2009-2014 PhD: Hong Kong University of Science and Technology
- 2014-2015 Postdoctoral Researcher: Hong Kong University of Science and Technology
- 2015-2016 Research Assistant Professor: Hong Kong University of Science and Technology
Publications
- Characterization of large-scale genomic differences in the first complete human genome, Lu Q, 2023
- The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development, Lu Q, 2024
- Structure of the BLUF protein TePixD Y8F mutant, Lu Q, 2023
- Cochlear transcript diversity and its role in auditory functions implied by an otoferlin short isoform, Lu Q, 2023
- Temporal and spatial assembly of inner ear hair cell ankle link condensate through phase separation, Lu Q, 2023
- Structurally divergent and recurrently mutated regions of primate genomes, Lu Q, 2023
- Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2, Lu Q, 2022
- A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity, Lu Q, 2022
- Effect of exercise and diet intervention in NAFLD and NASH via GAB2 methylation, Lu Q, 2021
- FCHSD2 cooperates with CDC42 and N-WASP to regulate cell protrusion formation, Lu Q, 2022
- Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex, Lu Q, 2016
- Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss, Lu Q, 2021
- Disruption of Cdh23 exon 68 splicing leads to progressive hearing loss in mice by affecting tip-link stability, Lu Q, 2023
Awards
- Shanghai Science and Technology Committee Young Talent Plan
- Shanghai Distinguished Professor (Oriental Scholar) Title
- Hong Kong Young Scientist Award
