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Geng Wu
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese
Anticancer
Biomolecular
Drug Development
Protein Design
Nucleic Acid Synthesis
Artificial Cells
Structural Biology
Cancer Therapy
Molecular Biology
Biochemistry
Areas of Focus
- Development of next-generation biomolecular anticancer drugs
- Design and synthesis of artificial proteins and nucleic acids
Work Experience
- 2001-2003: Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center
- 2003-2008: Postdoctoral Fellow, Harvard Medical School
- Since 2008: Professor, Shanghai Jiao Tong University
Academic Background & Achievements
- 1992-1997: Bachelor in Biology and Chemical Physics, University of Science and Technology of China
- 1997-2001: PhD in Chemistry, Princeton University
- Published in top journals including Nature and Science
- First student PhD supervised by Professor Yigong Shi
- Established the first structural biology lab at Shanghai Jiao Tong University
Publications
- The functional coupling between restriction and DNA phosphorothioation modification systems underlying the DndFGH restriction complex, Wu G*, Chen S*
- Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE, Wu G*, Wang L*, 2022
- Architecture of the Tuberous Sclerosis Protein Complex, Wu G*, 2020
- Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci, Wu G*, 2013
Awards
- 2005: Special Fellowship, Leukemia & Lymphoma Society
- 2008: Shanghai Eastern Scholar
- 2009: New Century Excellent Talents in University, Ministry of Education
- 2016: First Prize in Natural Science, Ministry of Education
