Professor | Han Xiao | Asia Growth Partners

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Name	Han Xiao
Contact Information	smallhan@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Han Xiao

Contact Information

smallhan@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	2012 - PhD in Microbiology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences Postdoctoral Research at University of Illinois at Urbana-Champaign, USA (2012-2015)
Work Experience	2015-present - Associate Researcher, Shanghai Jiao Tong University 2019-present - PhD Supervisor, Shanghai Jiao Tong University
Awards	2017 - Morning Star Outstanding Young Scholar Associate Professor Support Plan (Type B), Shanghai Jiao Tong University 2019 - DaSilva Award, Japanese Society for Biotechnology 2019, 2020 - Outstanding Class Director, Shanghai Jiao Tong University 2023 - Megia Engineering Award, Megia Technology

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

2012 - PhD in Microbiology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences
Postdoctoral Research at University of Illinois at Urbana-Champaign, USA (2012-2015)

Work Experience

2015-present - Associate Researcher, Shanghai Jiao Tong University
2019-present - PhD Supervisor, Shanghai Jiao Tong University

Awards

2017 - Morning Star Outstanding Young Scholar Associate Professor Support Plan (Type B), Shanghai Jiao Tong University
2019 - DaSilva Award, Japanese Society for Biotechnology
2019, 2020 - Outstanding Class Director, Shanghai Jiao Tong University
2023 - Megia Engineering Award, Megia Technology

Areas of Focus	Efficient Biomanufacturing Mushroom Synthetic Biology Genome Engineering
Publications	Biosynthesis of mushroom-derived type II ganoderic acids by engineered yeast, Wei Yuan, Chenjian Jiang, Qin Wang, Yubo Fang, Jin Wang, Meng Wang, Han Xiao, 2022 Rational engineering of a membrane-anchored promiscuous cytochrome P450 for efficient biosynthesis of valuable ganoderic acids, Yuhuan Luo, Zeqian Du, Chenjian Jiang, Ziqian Yu, Jian-Jiang Zhong, Ting Shi, Han Xiao, 2023 The aspartic protease Yps3p and cell wall glucanase Scw10p are novel determinants that enhance the secretion of the anti-tumor triterpenoid GA-HLDOA in Saccharomyces cerevisiae, Yubo Fang, Han Xiao, 2022 Efficient transport system of cultivated mushroom mycelium enables its derived carbon with high performance electrochemical desalination capability, Chen Zhao, Qin Wang, Shaozhong Chang, Shuo Zhang, Zhonghua Li, Zihan Shen, Xin Jin, Han Xiao, Huigang Zhang, 2022 Discovery and engineering of cytochrome P450s for terpenoid biosynthesis, Han Xiao, Yue Zhang, Meng Wang, 2019 Efficient biosynthesis of antitumor ganoderic acid HLDOA using a dual tunable system for optimizing the expression of CYP5150L8 and a Ganoderma P450 reductase, Xiaoting Lan, Wei Yuan, Meng Wang, Han Xiao, 2019 Biosynthesis of a ganoderic acid in Saccharomyces cerevisiae by expressing a cytochrome P450 gene from Ganoderma lucidum, Wen-Fang Wang, Han Xiao, Jian-Jiang Zhong, 2018 Genome-scale engineering of Saccharomyces cerevisiae with single nucleotide precision, Zehua Bao, Mohammad HamediRad, Pu Xue, Han Xiao, Ipek Tasan, Ran Chao, Jing Liang, Huimin Zhao, 2018 CRISPR-Cas9 assisted functional gene editing in the mushroom Ganoderma lucidum, Pingan Wang, Han Xiao, Jian-Jiang Zhong, 2020 Homology-Integrated CRISPR-Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae, Zehua Bao, Han Xiao, Jing Liang, Lu Zhang, Xiong Xiong, Ning Sun, Tong Si, Huimin Zhao, 2015

Areas of Focus

Efficient Biomanufacturing
Mushroom Synthetic Biology
Genome Engineering

Publications

Biosynthesis of mushroom-derived type II ganoderic acids by engineered yeast, Wei Yuan, Chenjian Jiang, Qin Wang, Yubo Fang, Jin Wang, Meng Wang, Han Xiao, 2022
Rational engineering of a membrane-anchored promiscuous cytochrome P450 for efficient biosynthesis of valuable ganoderic acids, Yuhuan Luo, Zeqian Du, Chenjian Jiang, Ziqian Yu, Jian-Jiang Zhong, Ting Shi, Han Xiao, 2023
The aspartic protease Yps3p and cell wall glucanase Scw10p are novel determinants that enhance the secretion of the anti-tumor triterpenoid GA-HLDOA in Saccharomyces cerevisiae, Yubo Fang, Han Xiao, 2022
Efficient transport system of cultivated mushroom mycelium enables its derived carbon with high performance electrochemical desalination capability, Chen Zhao, Qin Wang, Shaozhong Chang, Shuo Zhang, Zhonghua Li, Zihan Shen, Xin Jin, Han Xiao, Huigang Zhang, 2022
Discovery and engineering of cytochrome P450s for terpenoid biosynthesis, Han Xiao, Yue Zhang, Meng Wang, 2019
Efficient biosynthesis of antitumor ganoderic acid HLDOA using a dual tunable system for optimizing the expression of CYP5150L8 and a Ganoderma P450 reductase, Xiaoting Lan, Wei Yuan, Meng Wang, Han Xiao, 2019
Biosynthesis of a ganoderic acid in Saccharomyces cerevisiae by expressing a cytochrome P450 gene from Ganoderma lucidum, Wen-Fang Wang, Han Xiao, Jian-Jiang Zhong, 2018
Genome-scale engineering of Saccharomyces cerevisiae with single nucleotide precision, Zehua Bao, Mohammad HamediRad, Pu Xue, Han Xiao, Ipek Tasan, Ran Chao, Jing Liang, Huimin Zhao, 2018
CRISPR-Cas9 assisted functional gene editing in the mushroom Ganoderma lucidum, Pingan Wang, Han Xiao, Jian-Jiang Zhong, 2020
Homology-Integrated CRISPR-Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae, Zehua Bao, Han Xiao, Jing Liang, Lu Zhang, Xiong Xiong, Ning Sun, Tong Si, Huimin Zhao, 2015

Biomanufacturing Synthetic Biology Genome Engineering Genetic Determinants Chassis Cell Metabolites Biosynthesis Gene Editing Mushroom Metabolic Engineering

Qian Zhigang - Shanghai Jiao Tong University

Zai Gao Tan - Shanghai Jiao Tong University

Han Xiao - Shanghai Jiao Tong University

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