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Ruilian Yao
Life Science
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English, Japanese
Metabolic Engineering
Synthetic Biology
13C Analysis
Bioinformatics
Systems Biology
Gene-Protein Interactions
Metabolic Pathways
Disease Mechanisms
Biomedical Applications
Healthcare Technology
Areas of Focus
- 13C Metabolic Flux Analysis
- Development of computational analysis methods and software platforms for industrial microbial metabolism
- Mechanisms of major diseases' onset, progression, and outcomes
- Metabolomics, reflecting the interactions among genes, proteins, and metabolites on the metabolic network
Work Experience
- 2013-10 - Present: Associate Researcher at School of Life Sciences and Biotechnology, Shanghai Jiao Tong University
Academic Background & Achievements
- 2006 - Bachelor's Degree in Applied Physics from East China University of Science and Technology
- 2013 - PhD in Information Engineering from Kyushu Institute of Technology
Publications
- 13C metabolic flux analysis development over 30 years, Ruilian Yao, 2021
- 13C metabolic flux analysis-guided metabolic engineering of Escherichia coli for improved acetol production from glycerol, Ruilian Yao, Jiawei Li, Lei Feng, Xuehong Zhang, Hongbo Hu, 2019
- CRISPR-Cas9/Cas12a biotechnology and application in bacteria, Ruilian Yao, Di Liu, Xiao Jia, Yuan Zheng, Wei Liu, Yi Xiao, 2018
- Engineering and systems-level analysis of Pseudomonas chlororaphis for production of phenazine-1-carboxamide using glycerol as the cost-effective carbon source, Ruilian Yao, Keli Pan, Huasong Peng, Lei Feng, Hongbo Hu, Xuehong Zhang, 2018
- Elucidation of the co-metabolism of glycerol and glucose in Escherichia coli by genetic engineering, transcription, profiling, and 13C metabolic flux analysis, Ruilian Yao, Dewang Xiong, Hongbo Hu, Masataka Wakayama, Wenjuan Yu, Xuehong Zhang, Kazuyuki Shimizu, 2016
- Metabolic engineering of Escherichia coli to enhance acetol production from glycerol, Ruilian Yao, Qing Liu, Hongbo Hu, Thomas K. Wood, Xuehong Zhang, 2015
