Professor | Jie Yang | Asia Growth Partners

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Name	Jie Yang
Contact Information	yangjie@hust.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Jie Yang

Contact Information

yangjie@hust.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Huazhong University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2007-2013: Postdoctoral, Huazhong University of Science and Technology 2003-2006: PhD in Biomedical Engineering, Huazhong University of Science and Technology 1998-2001: Master in Crop Genetics and Breeding, Huazhong Agricultural University 1994-1998: Bachelor in Forestry, Huazhong Agricultural University
Work Experience	2013-2017: Vanderbilt University, Visiting Scholar 2007-2013: Huazhong University of Science and Technology, Lecturer 2001-2003: Biopharmaceutical Company, Product Development
Awards	2008: Outstanding Postdoctoral Fellow at Huazhong University of Science and Technology 2006-2008: Postdoctoral Science Foundation (30,000 RMB) 2008-2011: National Natural Science Foundation of China (200,000 RMB) 2008: First Prize, Natural Science Award of Hubei Province for research on optical molecular imaging for drug screening and efficacy evaluation

University/Lab Affiliation and Title

Huazhong University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2007-2013: Postdoctoral, Huazhong University of Science and Technology
2003-2006: PhD in Biomedical Engineering, Huazhong University of Science and Technology
1998-2001: Master in Crop Genetics and Breeding, Huazhong Agricultural University
1994-1998: Bachelor in Forestry, Huazhong Agricultural University

Work Experience

2013-2017: Vanderbilt University, Visiting Scholar
2007-2013: Huazhong University of Science and Technology, Lecturer
2001-2003: Biopharmaceutical Company, Product Development

Awards

2008: Outstanding Postdoctoral Fellow at Huazhong University of Science and Technology
2006-2008: Postdoctoral Science Foundation (30,000 RMB)
2008-2011: National Natural Science Foundation of China (200,000 RMB)
2008: First Prize, Natural Science Award of Hubei Province for research on optical molecular imaging for drug screening and efficacy evaluation

Areas of Focus	Biotechnology: Gene and Protein Engineering, Cell Biology, Protein Structure Analysis Fluorescent Proteins and Cell Imaging: Protein Optimization, Cell Imaging, Molecular Probe Design, Drug Activity Evaluation using Imaging, Protein-Protein Interaction Analysis, Bioluminescent Protein Imaging Neurobiology: Study of Neuronal Circuit Function using Optogenetic Proteins and Calcium Imaging, Neuronal Circuit Labeling using Modified Rabies Virus
Publications	Coupling Optogenetic Stimulation with NanoLuc-based Luminescence (BRET) Ca++ Sensing, Jie Yang, Derrick Cumberbatch, Samuel Centanni, Shu-qun Shi, Danny Winder, Donna Webb, Carl Hirschie Johnson, 2016 mBeRFP, an Improved Large Stokes Shift Red Fluorescent Protein, Jie Yang, Liang Wang, Fei Yang, Haiming Luo, Lingling Xu, Jinling Lu, Shaoqun Zeng, Zhihong Zhang, 2013 Low false-positives in an mLumin-based bimolecular fluorescence complementation system with a bicistronic expression vector, Shun Liu, Xiangyong Li, Jie Yang, Zhihong Zhang, 2014 LC3 fluorescent puncta in autophagosomes or in protein aggregates can be distinguished by FRAP analysis in living cells, Liang Wang, Min Chen, Jie Yang, Zhihong Zhang, 2013 Enhanced dynamic range in a genetically encoded Ca2+ sensor, Shun Liu, Jun He, Honglin Jin, Fei Yang, Jinling Lu, Jie Yang, 2011 Tetrameric far-red fluorescent protein as a scaffold to assemble an octavalent peptide nanoprobe for enhanced tumor targeting and intracellular uptake in vivo, Haiming Luo, Jie Yang, Honglin Jin, Chuan Huang, Jianwei Fu, Fei Yang, Hui Gong, Shaoqun Zeng, Qingming Luo, Zhihong Zhang, 2011 A Ligation-independent Cloning Method Using Nicking DNA Endonuclease, Jie Yang, Zhihong Zhang, Xin A Zhang, Qingming Luo, 2010 Recent Progress in Fluorescent Proteins Research, Jie Yang, Zhihong Zhang, Qingming Luo, 2010 Fluorescence imaging to assess the matrix metalloproteinase (MMP) activity and its inhibitor in vivo, Zhihong Zhang, Jie Yang, Jinling Lu, Juqiang Lin, Shaoqun Zeng, Qingming Luo, 2008 Detection of MMP activity in living cells by a genetically encoded surface-displayed FRET sensor, Jie Yang, Zhihong Zhang, Juqiang Lin, Jinling Lu, Bi-feng Liu, Shaoqun Zeng, Qingming Luo, 2007 Real-time detecting gelatinases activity in living cells by FRET imaging, Jie Yang, Zhihong Zhang, Bifeng Liu, Qingming Luo, 2006 Real-time detection of caspase-2 activation in a single living HeLa cell during cisplatin-induced apoptosis, Juqing Lin, Zhihong Zhang, Jie Yang, Shaoqun Zeng, Bi-feng Liu, Qingming Luo, 2006 A novel far-red bimolecular fluorescence complementation system that allows for efficient visualization of protein interactions under physiological conditions, Jun Chu, Zhihong Zhang, Ying Zheng, Jie Yang, Linsong Qin, Jinling Lu, Zhenli Huang, Shaoqun Zeng, Qingming Luo, 2009 Visualization of β-Secretase cleavage in living cells using a genetically encoded surface-displayed FRET Probe, Jinling Lu, Zhihong Zhang, Jie Yang, Jun Chu, Pengcheng Li, Shaoqun Zeng, Qingming Luo, 2007 Optical encoding of microbeads based on silica particle encapsulated quantum dots and its applications, Xiao-Xia Zhu, Yuan-Cheng Cao, Xin Jin, Jie Yang, Xiao-Feng Hua, Hai-Qiao Wang, Bo Liu, ZhanWang, Jian-HaoWang, Liang Yang, Yuan-Di Zhao, 2008 Detection of BACE cleavage in the secretary pathway, Jinling Lu, Jie Yang, Jun Chu, Shaoqun Zeng, Zhihong Zhang, 2007 Detection of β-Secretase Dimerization in Living Cells Using Acceptor Photobleaching FRET, Jinling Lu, Jun Chu, Jie Yang, Shaoqun Zeng, Luo, Q., Zhang, Z., 2008

Areas of Focus

Biotechnology: Gene and Protein Engineering, Cell Biology, Protein Structure Analysis
Fluorescent Proteins and Cell Imaging: Protein Optimization, Cell Imaging, Molecular Probe Design, Drug Activity Evaluation using Imaging, Protein-Protein Interaction Analysis, Bioluminescent Protein Imaging
Neurobiology: Study of Neuronal Circuit Function using Optogenetic Proteins and Calcium Imaging, Neuronal Circuit Labeling using Modified Rabies Virus

Publications

Coupling Optogenetic Stimulation with NanoLuc-based Luminescence (BRET) Ca++ Sensing, Jie Yang, Derrick Cumberbatch, Samuel Centanni, Shu-qun Shi, Danny Winder, Donna Webb, Carl Hirschie Johnson, 2016
mBeRFP, an Improved Large Stokes Shift Red Fluorescent Protein, Jie Yang, Liang Wang, Fei Yang, Haiming Luo, Lingling Xu, Jinling Lu, Shaoqun Zeng, Zhihong Zhang, 2013
Low false-positives in an mLumin-based bimolecular fluorescence complementation system with a bicistronic expression vector, Shun Liu, Xiangyong Li, Jie Yang, Zhihong Zhang, 2014
LC3 fluorescent puncta in autophagosomes or in protein aggregates can be distinguished by FRAP analysis in living cells, Liang Wang, Min Chen, Jie Yang, Zhihong Zhang, 2013
Enhanced dynamic range in a genetically encoded Ca2+ sensor, Shun Liu, Jun He, Honglin Jin, Fei Yang, Jinling Lu, Jie Yang, 2011
Tetrameric far-red fluorescent protein as a scaffold to assemble an octavalent peptide nanoprobe for enhanced tumor targeting and intracellular uptake in vivo, Haiming Luo, Jie Yang, Honglin Jin, Chuan Huang, Jianwei Fu, Fei Yang, Hui Gong, Shaoqun Zeng, Qingming Luo, Zhihong Zhang, 2011
A Ligation-independent Cloning Method Using Nicking DNA Endonuclease, Jie Yang, Zhihong Zhang, Xin A Zhang, Qingming Luo, 2010
Recent Progress in Fluorescent Proteins Research, Jie Yang, Zhihong Zhang, Qingming Luo, 2010
Fluorescence imaging to assess the matrix metalloproteinase (MMP) activity and its inhibitor in vivo, Zhihong Zhang, Jie Yang, Jinling Lu, Juqiang Lin, Shaoqun Zeng, Qingming Luo, 2008
Detection of MMP activity in living cells by a genetically encoded surface-displayed FRET sensor, Jie Yang, Zhihong Zhang, Juqiang Lin, Jinling Lu, Bi-feng Liu, Shaoqun Zeng, Qingming Luo, 2007
Real-time detecting gelatinases activity in living cells by FRET imaging, Jie Yang, Zhihong Zhang, Bifeng Liu, Qingming Luo, 2006
Real-time detection of caspase-2 activation in a single living HeLa cell during cisplatin-induced apoptosis, Juqing Lin, Zhihong Zhang, Jie Yang, Shaoqun Zeng, Bi-feng Liu, Qingming Luo, 2006
A novel far-red bimolecular fluorescence complementation system that allows for efficient visualization of protein interactions under physiological conditions, Jun Chu, Zhihong Zhang, Ying Zheng, Jie Yang, Linsong Qin, Jinling Lu, Zhenli Huang, Shaoqun Zeng, Qingming Luo, 2009
Visualization of β-Secretase cleavage in living cells using a genetically encoded surface-displayed FRET Probe, Jinling Lu, Zhihong Zhang, Jie Yang, Jun Chu, Pengcheng Li, Shaoqun Zeng, Qingming Luo, 2007
Optical encoding of microbeads based on silica particle encapsulated quantum dots and its applications, Xiao-Xia Zhu, Yuan-Cheng Cao, Xin Jin, Jie Yang, Xiao-Feng Hua, Hai-Qiao Wang, Bo Liu, ZhanWang, Jian-HaoWang, Liang Yang, Yuan-Di Zhao, 2008
Detection of BACE cleavage in the secretary pathway, Jinling Lu, Jie Yang, Jun Chu, Shaoqun Zeng, Zhihong Zhang, 2007
Detection of β-Secretase Dimerization in Living Cells Using Acceptor Photobleaching FRET, Jinling Lu, Jun Chu, Jie Yang, Shaoqun Zeng, Luo, Q., Zhang, Z., 2008

Gene Engineering Protein Engineering Cell Biology Protein Structure Fluorescent Proteins Cell Imaging Molecular Probes Drug Evaluation Protein Interactions Neurobiology

Lu Qing - Shanghai Jiao Tong University

Faxiang Li - Central South University

Maojun Yang - Tsinghua University

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