Professor | Jun Tang | Asia Growth Partners

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Name	Jun Tang
Contact Information	jtang@cau.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Jun Tang

Contact Information

jtang@cau.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	China Agricultural University
Faculty	Veterinary Medicine
Academic Background & Achievements	1991 - Bachelor of Science in Biochemistry: Lanzhou University 1995-2001 - PhD in Molecular and Cellular Biology: University of Massachusetts, Supervisor: David Gross Selected for the Ministry of Education's New Century Excellent Talents Support Plan in 2010
Work Experience	2001-2006 - Postdoctoral Researcher, Cancer Center, University of Pennsylvania 2006-2008 - Research Associate, Cancer Center, University of Pennsylvania 2009-present - Professor, College of Veterinary Medicine, China Agricultural University

University/Lab Affiliation and Title

China Agricultural University

Faculty

Veterinary Medicine

Academic Background & Achievements

1991 - Bachelor of Science in Biochemistry: Lanzhou University
1995-2001 - PhD in Molecular and Cellular Biology: University of Massachusetts, Supervisor: David Gross
Selected for the Ministry of Education's New Century Excellent Talents Support Plan in 2010

Work Experience

2001-2006 - Postdoctoral Researcher, Cancer Center, University of Pennsylvania
2006-2008 - Research Associate, Cancer Center, University of Pennsylvania
2009-present - Professor, College of Veterinary Medicine, China Agricultural University

Areas of Focus	Tumor cell signal transduction Animal antiviral infection mechanisms Comparative oncology and signaling transduction Herpes virus and host interaction Subnuclear structures (PML-NBs) function and regulation Antitumor and antiviral activities of chemical small molecules
Publications	Pseudorabies Virus DNA Polymerase Processivity Factor UL42 Inhibits Type I Interferon Response by Preventing ISGF3-ISRE Interaction, Zhang R, Chen S, Zhang Y, Wang M, Qin C, Yu C, Zhang Y, Li Y, Chen L, Zhang X, Yuan X, Tang J, 2021 Swine Promyelocytic Leukemia Isoform II Inhibits Pseudorabies Virus Infection by Suppressing Viral Gene Transcription in PML-NBs, Yu C, Xu A, Lang Y, Qin C, Yuan X, Feng W, Wang M, Gao C, Chen J, Zhang R, Tang J, 2020 HLA-B-associated transcript 3 (Bat3) stabilizes and activates p53 in a HAUSP-dependent manner, Zhang R, Cui D, Xue T, Lang Y, Li, Sun H, Kuang Y, Li G, Tang J, 2020 Bclaf1 is a direct target of HIF-1 and critically regulates the stability of HIF-1α under hypoxia, Shao A, Lang Y, Wang M, Qin C, Kuang Y, Mei Y, Lin D, Zhang S, Tang J, 2020 Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3, Qin C, Zhang R, Lang Y, Shao A, Xu A, Feng W, Han J, Wang M, He W, Yu C, Tang J, 2019 C-terminal motifs in promyelocytic leukemia protein isoforms critically regulate PML nuclear body formation, Li, C., Peng, Q., Wan, X., Sun, H., Tang J, 2017 Pseudorabies Virus dUTPase UL50 Induces Lysosomal Degradation of Type I Interferon Receptor 1 and Antagonizes the Alpha Interferon Response, Zhang R, Xu A, Qin C, Zhang Q, Chen S, Lang Y, Wang M, Li C, Feng W, Zhang R, Jiang Z, Tang J, 2017 Bclaf1 is an important NF-kappaB signaling transducer and C/EBPbeta regulator in DNA damage-induced senescence, Shao, A.W., Sun, H., Geng, Y., Peng, Q., Wang, P., Chen, J., Xiong, T., Cao, R., Tang J, 2016 Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation, Zheng J, Lang Y, Zhang Q, Cui D, Sun H, Jiang J, Jiang L, Chen Z, Zhang R, Gao Y, Tian W, Wu W, Tang J, Chen Z, 2015 The ribosomal protein S26 regulates p53 activity in response to DNA damage, Cui D., Li LJ, Lou HJ., Sun HL, Ngai S-M, Shao GZ, Tang J, 2014

Areas of Focus

Tumor cell signal transduction
Animal antiviral infection mechanisms
Comparative oncology and signaling transduction
Herpes virus and host interaction
Subnuclear structures (PML-NBs) function and regulation
Antitumor and antiviral activities of chemical small molecules

Publications

Pseudorabies Virus DNA Polymerase Processivity Factor UL42 Inhibits Type I Interferon Response by Preventing ISGF3-ISRE Interaction, Zhang R, Chen S, Zhang Y, Wang M, Qin C, Yu C, Zhang Y, Li Y, Chen L, Zhang X, Yuan X, Tang J, 2021
Swine Promyelocytic Leukemia Isoform II Inhibits Pseudorabies Virus Infection by Suppressing Viral Gene Transcription in PML-NBs, Yu C, Xu A, Lang Y, Qin C, Yuan X, Feng W, Wang M, Gao C, Chen J, Zhang R, Tang J, 2020
HLA-B-associated transcript 3 (Bat3) stabilizes and activates p53 in a HAUSP-dependent manner, Zhang R, Cui D, Xue T, Lang Y, Li, Sun H, Kuang Y, Li G, Tang J, 2020
Bclaf1 is a direct target of HIF-1 and critically regulates the stability of HIF-1α under hypoxia, Shao A, Lang Y, Wang M, Qin C, Kuang Y, Mei Y, Lin D, Zhang S, Tang J, 2020
Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3, Qin C, Zhang R, Lang Y, Shao A, Xu A, Feng W, Han J, Wang M, He W, Yu C, Tang J, 2019
C-terminal motifs in promyelocytic leukemia protein isoforms critically regulate PML nuclear body formation, Li, C., Peng, Q., Wan, X., Sun, H., Tang J, 2017
Pseudorabies Virus dUTPase UL50 Induces Lysosomal Degradation of Type I Interferon Receptor 1 and Antagonizes the Alpha Interferon Response, Zhang R, Xu A, Qin C, Zhang Q, Chen S, Lang Y, Wang M, Li C, Feng W, Zhang R, Jiang Z, Tang J, 2017
Bclaf1 is an important NF-kappaB signaling transducer and C/EBPbeta regulator in DNA damage-induced senescence, Shao, A.W., Sun, H., Geng, Y., Peng, Q., Wang, P., Chen, J., Xiong, T., Cao, R., Tang J, 2016
Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation, Zheng J, Lang Y, Zhang Q, Cui D, Sun H, Jiang J, Jiang L, Chen Z, Zhang R, Gao Y, Tian W, Wu W, Tang J, Chen Z, 2015
The ribosomal protein S26 regulates p53 activity in response to DNA damage, Cui D., Li LJ, Lou HJ., Sun HL, Ngai S-M, Shao GZ, Tang J, 2014

Oncology Cell Signaling Viral Infection Host Interaction Pml Nuclear Bodies Chemical Molecules Antiviral Antitumor Comparative Medicine Signal Pathways

Zhen Wu - Sichuan Agricultural University

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