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Qinghua Tao
Life Science
Tsinghua University
Beijing
Language: Chinese, English
Genomics
Proteomics
Molecular Biology
Genetics
Cell Fate
Differentiation
Transgenerational
Metabolic Regulation
Self-Organization
Growth Factors
Areas of Focus
- Molecular mechanisms of cell fate determination and differentiation in early vertebrate embryogenesis
- Transgenerational regulatory mechanisms of embryonic development
- Metabolic regulation and self-organization in fertilized eggs and early embryos
- Mechanisms of directed differentiation of embryonic pluripotent cells induced by growth factors like Wnt, TGF-β, FGF
Work Experience
- 2000-2008 Postdoctoral Researcher, Research Assistant: Cincinnati Children's Hospital Medical Center, Department of Developmental Biology, USA
- 2008-present Professor: Tsinghua University, School of Life Sciences
Academic Background & Achievements
- 1988-1992 Bachelor in Genetics: Sichuan University
- 1995-2000 PhD in Developmental Biology: Shanghai Institute of Cell Biology, Chinese Academy of Sciences
Publications
- Lysosomal degradation of the maternal dorsal determinant Hwa to safeguard dorsal body axis formation, Zhu XC, Wang P, Wei JL, Li YY, Zhai JY, Zheng TR, Tao QH*, 2021
- The Cytokine FAM3B/PANDER is an FGFR Ligand that Promotes Posterior Development in Xenopus, Zhang FF, Zhuc XC, Wang P, He Q, Huang HM, Zheng TR, Li YY, Jia H, Xu LP, Zhao HX, Colozza G, Tao QH*, De Robertis EM*, Ding Y*, 2021
- Maternal Huluwa Dictates the Embryonic Body Axis through b-catenin in Vertebrates, Yan L, Chen J, Zhu XC, Sun JW, Wu XT, Shen WM, Zhang WY, Tao QH*, Meng AM*, 2018
- KDM3A-mediated dimethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis, Lin H, Zhu XC, Chen G, Song L, Gao L, Khand AA, Chen Y, Lin GF*, Tao QH*, 2017
- The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus, Zhu XC, Xing R, Tan RB, Dai RY, Tao QH, 2017
- A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT function, Gao L, Zhu XC, Chen G, Ma X, Zhang Y, Khand A, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao QH*, 2016
- The MLL/Setd1b methyltransferase is required for the Spemann’s organizer gene activation in Xenopus, Lin H, Min Z, Tao QH*, 2016
- NEDD4L regulates convergent extension movements in Xenopus embryos via Dishevelled-mediated non-canonical Wnt signaling, Zhang Y, Ding Y, Chen YG*, Tao QH*, 2014
- HECT Domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting Dishevelled for proteasomal degradation, Ding Y, Zhang Y, Xu C, Tao QH* and Chen YG*, 2013
- Maternal Wnt11 activates the canonical Wnt signaling pathway required for axis formation in Xenopus embryos, Tao QH, Yokota C, Puck H, Kofron M, Birsoy B, Dong Y, Asashima M, Wylie C, Lin X and Heasman J., 2005
