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Chen Zhucheng
Life Science
Tsinghua University
Beijing
Language: English, Chinese
Chromatin
Remodeling
Epigenetics
Nucleosome
Dna Methylation
Histone Modification
Chromatin Structure
Gene Transcription
Cell Fate
Human Diseases
Areas of Focus
- Chromatin remodeling and epigenetic mechanisms
Work Experience
- 2011-Present - Tsinghua University, School of Life Sciences - Associate Professor, Professor
Academic Background & Achievements
- 1994-1998 Bachelor's Degree: Nankai University
- 1998-2001 Master's Degree: Peking University
- 2001-2003 Master's Degree: New York University
- 2003-2008 PhD: Cornell University
- 2008-2011 Postdoctoral Researcher: University of Texas Southwestern Medical Center
Publications
- Structure of human PBAF chromatin remodeling complex bound to a nucleosome, Yuan J, Chen K, Zhang W, Chen Z, 2022
- Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome, Wang L, Chen K, Chen Z, 2021
- Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity, He Z, Chen K, Ye Y, Chen Z, 2021
- Structure of the RSC complex bound to the nucleosome, Ye Y, Wu H, Chen K, Clapier CR, Verma N, Zhang W, Deng H, Cairns BR, Gao N, Chen Z, 2019
- Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling, Yan L, Wu H, Li X, Gao N, Chen Z, 2019
- Mechanism of DNA translocation underlying chromatin remodeling by Snf2, Li M, Xia X, Tian Y, Jia Q, Liu X, Ying L, Li M, Li X, Chen Z, 2019
- Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure, Liu X, Li M, Xia X, Li X, Chen Z, 2017
- Structure and regulation of the chromatin remodeller ISWI, Yan L, Wang L, Tian Y, Xia X, Chen Z, 2016
- The NuA4 core complex acetylates nucleosomal histone H4 through a double recognition mechanism, Xu P, Li C, Chen Z, Jiang S, Fan S, Wang J, Dai J, Zhu P, Chen Z, 2016
- Crystal structure of a nuclear actin ternary complex, Cao T, Sun L, Jiang Y, Huang S, Wang J, Chen Z, 2016
- Structure of chromatin remodeller Swi2/Snf2 in the resting state, Xia X, Liu X, Li T, Fang X, Chen Z, 2016
