Areas of Focus
- Development and application of X-ray crystallography and cryo-EM methods
- Structural biology of significant membrane proteins and submicroscopic structures in cell division
- Structure and function of spliceosomes in eukaryotic cells and mechanisms of precursor mRNA splicing
Work Experience
- 2019-present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor
Academic Background & Achievements
- 2005-2009 Bachelor: Tsinghua University
- 2009-2015 PhD: Tsinghua University
- 2015-2019 Postdoctoral Researcher: Tsinghua University
Publications
- Molecular Mechanisms of pre-mRNA Splicing through Structural Biology of the Spliceosome, Yan, C.; Wan, R.; Shi, Y., 2019
- Structures of the human spliceosomes before and after release of the ligated exon, Zhang, X.; Zhan, X.; Yan, C.; Zhang, W.; Lei, J.; Shi, Y., 2019