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Zhi John Lu
Life Science
Tsinghua University
Beijing
Language: English, Chinese
Bioinformatics
Precision Medicine
Cancer
Autoimmune Diseases
Ai
Machine Learning
Genetic Information
Dna
Rna
Early Detection
Areas of Focus
- Development of bioinformatics technologies and their application in precision medicine for complex diseases such as cancer and autoimmune diseases
- Use of AI technologies like machine learning to study genetic information encoded in structured DNA and RNA molecules and their interactions within biological systems
- Early detection of cancer through bioinformatics-driven precision medicine
- AI-driven RNA target and drug design
Work Experience
- 2011-2016 - Tsinghua University - Assistant Professor, Doctoral Supervisor
- 2017-present - Tsinghua University - Associate Professor, Doctoral Supervisor
Academic Background & Achievements
- 1998-2003 Bachelor: University of Science and Technology of China, School of Life Sciences
- 2003-2008 PhD: University of Rochester, Biophysics
- 2008-2011 Postdoctoral: Yale University, Bioinformatics
Publications
- cfOmics: a cell-free multi-Omics database for diseases, Mingyang Li, Tianxiu Zhou, Mingfei Han, Hongke Wang, Pengfei Bao, Yuhuan Tao, Xiaoqing Chen, Guansheng Wu, Tianyou Liu, Xiaojuan Wang, Qian Lu, Yunping Zhu, Zhi John Lu, 2024
- Cell-free multi-omics analysis reveals potential biomarkers in gastrointestinal cancer patients’ blood, Yuhuan Tao, Shaozhen Xing, Shuai Zuo, Pengfei Bao, Yunfan Jin, Yu Li, Yingchao Wu, Shanwen Chen, Xiaojuan Wang, Yumin Zhu, Ying Feng, Xiaohua Zhang, Xianbo Wang, Qiaoran Xi, Qian Lu, Pengyuan Wang, Zhi John Lu, 2023
- Cancer Type Classification Using Plasma Cell Free RNAs Derived from Human and Microbes, Shanwen Chen, Yunfan Jin, Siqi Wang, Shaozhen Xing, Zhenjiang Zech Xu, Zhi John Lu, Pengyuan Wang, 2022
- POSTAR3: an updated platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins, Weihao Zhao, Shang Zhang, Yucheng T Yang, Zhi John Lu, 2022
- Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer, Shuaishuai Teng, Yang Eric Li, Zhi John Lu, Dong Wang, 2020
- Ribosome elongating footprints denoised by wavelet transform comprehensively characterize dynamic cellular translation events, Zhiyu Xu, Long Hu, Dong Wang, Zhi John Lu, 2018
- Stress-responsive regulation of long noncoding RNAs’ polyadenylation in Oryza sativa, Jiapei Yuan, Jingrui Li, Yijun Qi, Zhi John Lu, 2018
- An Integrated Encyclopedia of DNA Elements in the Human Genome, ENCODE Project Consortium, Lu Z, 2012
- Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project, Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, et al., 2010
Awards
- Ho Leung Ho Lee Foundation Youth Fund recipient
- New Century Talent Support Plan recipient
