Professor | Zhi John Lu | Asia Growth Partners

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Name	Zhi John Lu
Contact Information	{'en': 'Tel/FAX: +86-10-62789217, E-mail: lulab1 AT tsinghua.edu.cn', 'zh': '电话/传真: +86-10-62789217, 电子邮件: lulab1 AT tsinghua.edu.cn', 'de': 'Tel./FAX: +86-10-62789217, E-Mail: lulab1 AT tsinghua.edu.cn'}
Language ability	English, Chinese
Province	Beijing

Upload Avatar (500 x 500)

Name

Zhi John Lu

Contact Information

{'en': 'Tel/FAX: +86-10-62789217, E-mail: lulab1 AT tsinghua.edu.cn', 'zh': '电话/传真: +86-10-62789217, 电子邮件: lulab1 AT tsinghua.edu.cn', 'de': 'Tel./FAX: +86-10-62789217, E-Mail: lulab1 AT tsinghua.edu.cn'}

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	1998-2003 Bachelor: University of Science and Technology of China, School of Life Sciences 2003-2008 PhD: University of Rochester, Biophysics 2008-2011 Postdoctoral: Yale University, Bioinformatics
Work Experience	2011-2016 - Tsinghua University - Assistant Professor, Doctoral Supervisor 2017-present - Tsinghua University - Associate Professor, Doctoral Supervisor
Awards	Ho Leung Ho Lee Foundation Youth Fund recipient New Century Talent Support Plan recipient

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

1998-2003 Bachelor: University of Science and Technology of China, School of Life Sciences
2003-2008 PhD: University of Rochester, Biophysics
2008-2011 Postdoctoral: Yale University, Bioinformatics

Work Experience

2011-2016 - Tsinghua University - Assistant Professor, Doctoral Supervisor
2017-present - Tsinghua University - Associate Professor, Doctoral Supervisor

Awards

Ho Leung Ho Lee Foundation Youth Fund recipient
New Century Talent Support Plan recipient

Areas of Focus	Development of bioinformatics technologies and their application in precision medicine for complex diseases such as cancer and autoimmune diseases Use of AI technologies like machine learning to study genetic information encoded in structured DNA and RNA molecules and their interactions within biological systems Early detection of cancer through bioinformatics-driven precision medicine AI-driven RNA target and drug design
Publications	cfOmics: a cell-free multi-Omics database for diseases, Mingyang Li, Tianxiu Zhou, Mingfei Han, Hongke Wang, Pengfei Bao, Yuhuan Tao, Xiaoqing Chen, Guansheng Wu, Tianyou Liu, Xiaojuan Wang, Qian Lu, Yunping Zhu, Zhi John Lu, 2024 Cell-free multi-omics analysis reveals potential biomarkers in gastrointestinal cancer patients’ blood, Yuhuan Tao, Shaozhen Xing, Shuai Zuo, Pengfei Bao, Yunfan Jin, Yu Li, Yingchao Wu, Shanwen Chen, Xiaojuan Wang, Yumin Zhu, Ying Feng, Xiaohua Zhang, Xianbo Wang, Qiaoran Xi, Qian Lu, Pengyuan Wang, Zhi John Lu, 2023 Cancer Type Classification Using Plasma Cell Free RNAs Derived from Human and Microbes, Shanwen Chen, Yunfan Jin, Siqi Wang, Shaozhen Xing, Zhenjiang Zech Xu, Zhi John Lu, Pengyuan Wang, 2022 POSTAR3: an updated platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins, Weihao Zhao, Shang Zhang, Yucheng T Yang, Zhi John Lu, 2022 Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer, Shuaishuai Teng, Yang Eric Li, Zhi John Lu, Dong Wang, 2020 Ribosome elongating footprints denoised by wavelet transform comprehensively characterize dynamic cellular translation events, Zhiyu Xu, Long Hu, Dong Wang, Zhi John Lu, 2018 Stress-responsive regulation of long noncoding RNAs’ polyadenylation in Oryza sativa, Jiapei Yuan, Jingrui Li, Yijun Qi, Zhi John Lu, 2018 An Integrated Encyclopedia of DNA Elements in the Human Genome, ENCODE Project Consortium, Lu Z, 2012 Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project, Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, et al., 2010

Areas of Focus

Development of bioinformatics technologies and their application in precision medicine for complex diseases such as cancer and autoimmune diseases
Use of AI technologies like machine learning to study genetic information encoded in structured DNA and RNA molecules and their interactions within biological systems
Early detection of cancer through bioinformatics-driven precision medicine
AI-driven RNA target and drug design

Publications

cfOmics: a cell-free multi-Omics database for diseases, Mingyang Li, Tianxiu Zhou, Mingfei Han, Hongke Wang, Pengfei Bao, Yuhuan Tao, Xiaoqing Chen, Guansheng Wu, Tianyou Liu, Xiaojuan Wang, Qian Lu, Yunping Zhu, Zhi John Lu, 2024
Cell-free multi-omics analysis reveals potential biomarkers in gastrointestinal cancer patients’ blood, Yuhuan Tao, Shaozhen Xing, Shuai Zuo, Pengfei Bao, Yunfan Jin, Yu Li, Yingchao Wu, Shanwen Chen, Xiaojuan Wang, Yumin Zhu, Ying Feng, Xiaohua Zhang, Xianbo Wang, Qiaoran Xi, Qian Lu, Pengyuan Wang, Zhi John Lu, 2023
Cancer Type Classification Using Plasma Cell Free RNAs Derived from Human and Microbes, Shanwen Chen, Yunfan Jin, Siqi Wang, Shaozhen Xing, Zhenjiang Zech Xu, Zhi John Lu, Pengyuan Wang, 2022
POSTAR3: an updated platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins, Weihao Zhao, Shang Zhang, Yucheng T Yang, Zhi John Lu, 2022
Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer, Shuaishuai Teng, Yang Eric Li, Zhi John Lu, Dong Wang, 2020
Ribosome elongating footprints denoised by wavelet transform comprehensively characterize dynamic cellular translation events, Zhiyu Xu, Long Hu, Dong Wang, Zhi John Lu, 2018
Stress-responsive regulation of long noncoding RNAs’ polyadenylation in Oryza sativa, Jiapei Yuan, Jingrui Li, Yijun Qi, Zhi John Lu, 2018
An Integrated Encyclopedia of DNA Elements in the Human Genome, ENCODE Project Consortium, Lu Z, 2012
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project, Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, et al., 2010

Bioinformatics Precision Medicine Cancer Autoimmune Diseases Ai Machine Learning Genetic Information Dna Rna Early Detection

Qi Liu - Tongji University

Dong-Qing Wei - Shanghai Jiao Tong University

Jingkang Guo - Shanghai University

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