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Zhen Li
Life Science
Tsinghua University
Beijing
Language: English, Chinese
Adiponectin
Multimerization
Secretion
Molecular Mechanisms
Type 2 Diabetes
Drug Targets
Screening
Identification
Novel Targets
Biomedical Research
Areas of Focus
- Molecular mechanisms of adiponectin multimerization and secretion
- Screening and identification of novel drug targets for Type 2 Diabetes
Work Experience
- 2000-2003 - Hong Kong University of Science and Technology - Associate Researcher
- 2004-Present - Tsinghua University, School of Life Sciences - Associate Professor, Professor
Academic Background & Achievements
- 1988 Bachelor: Wuhan University
- 1995 PhD: Carnegie Mellon University, USA
- 1995-1997 Postdoctoral Researcher: University of Michigan, USA
- 1997-1999 Postdoctoral Researcher: Stanford University, USA
Publications
- Comprehensive comparisons between grafted Kynam Agarwood and normal Agarwood on traits, composition, and in vitro activation of AMPK, Chen F, Huang Y, Luo L, Wang Q, Huang N, Zhang ZJ, Li Z, 2023
- WSF-7 inhibits obesity-mediated PPARgamma phosphorylation and improves insulin sensitivity in 3T3-L1 adipocytes, Zhang YD, Wang YY, Li, XC, Gu, KR, Li MX, Zhang Y, Zhang ZJ, Wang SF, Li Z, 2020
- WSF-P-1, a novel AMPK activator, promotes adiponectin multimerization in 3T3-L1 adipocytes, Wang Y, Zhang Y, Wang Y, Peng H, Rui J, Zhang Z, Wang S, Li Z, 2017
- Evodiamine activates AMPK and promotes adiponectin multimerization in 3T3-L1 adipocytes, Liu LH, Xie JY, Guo WW, Wu GY, Chen ZF, Yi JY, Zhang L, Zhang ZJ, Li Z, 2014
- Pseudoginsenoside F11, a Novel Partial PPARγ Agonist, Promotes Adiponectin Oligomerization and Secretion in 3T3-L1 Adipocytes, Wu G, Yi J, Liu L, Wang P, Zhang Z, Li Z, 2013
- Promotion of adiponectin multimerization by emodin, a novel AMPK activator with PPARγ-agonist activity, Chen Z, Zhang L, Yi J, Yang Z, Zhang Z, Li Z, 2012
- Tanshinone IIA promotes the assembly of adiponectin in 3T3-L1 adipocytes, Lin H, Li Y, Li Y, Yi J, Mai Y, Li Z, 2012
- Adiponectin self-regulates its expression and multimerization in adipose tissue: an autocrine/paracrine mechanism?, Lin H, Li Z, 2012
- Activation of AMPK by berberine promotes adiponectin multimerization in 3T3-L1 adipocytes, Li Y, Wang P, Zhuang Y, Lin H, Li Y, Liu L, Meng Q, Cui T, Liu J, Li Z, 2011
Awards
- 2004: Selected for the Ministry of Education's 'New Century Excellent Talents Support Plan'
- 2008: Awarded 'Beijing Education Innovation Pioneer' by Beijing Federation of Trade Unions
- 2011: First Prize 'Excellent Class Director at Tsinghua University'
- 2012: Second 'Zheng Changxue Excellent Teaching Award'
