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Gao Ning
Life Science
Peking University
Beijing
Language: English, Chinese
Ribosome
Biogenesis
Protein
Biosynthesis
Regulation
Dna
Replication
Initiation
Molecular Biology
Cell Biology
Areas of Focus
- Ribosome biogenesis
- Protein biosynthesis regulation
- DNA replication initiation regulation
Work Experience
- 2017/4-present, Professor, School of Life Sciences, Peking University
- 2017/4-present, Researcher, Joint Life Sciences Center, Peking University-Tsinghua University
- 2008/11-2017/3, Special Associate Researcher, Assistant Professor, Associate Professor (with tenure), Professor, School of Life Sciences, Tsinghua University
- 2006-2008, Postdoctoral Fellow, Wadsworth Center, Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University
Academic Background & Achievements
- 2001-2006 PhD, Department of Biomedical Sciences, University at Albany, SUNY
- 1996-2000 Bachelor, School of Life Sciences, Peking University
Publications
- N-terminal signal peptides facilitate the engineering of PVC complex as a potent protein delivery system, Jiang, F., Shen, J., Cheng, J., Wang, X., Yang, J., Li, N., Gao, N., and Jin, Q., 2022
- Ribosomal protein eL39 is important for maturation of the nascent polypeptide exit tunnel and proper protein folding during translation, Micic, J., Rodriguez-Galan, O., Babiano, R., Fitzgerald, F., Fernandez-Fernandez, J., Zhang, Y., Gao, N., Woolford, J.L., and de la Cruz, J., 2022
- Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase, Cheng, J., Li, N., Huo, Y., Dang, S., Tye, B.-K., Gao, N., and Zhai, Y., 2022
- Structural insights into how GlcNAc-1-phosphotransferase directs lysosomal protein transport, Du, S., Wang, G., Zhang, Z., Ma, C., Gao, N., and Xiao, J., 2022
- Engineering and functional analysis of yeast with a monotypic 40S ribosome subunit, Hu, X., Jiang, S., Xu, F., Zeng, C., Wang, X., Liu, W., Cheng, A., Ma, C., Gao, N., Zhao, Y., Dai, J., and Zhao, G., 2022
- Structural insights into the membrane microdomain organization by SPFH family proteins, Ma, C., Wang, C., Luo, D., Yan, L., Yang, W., Li, N., and Gao, N., 2022
- Characterization of Photorhabdus Virulence Cassette as a causative agent in the emerging pathogen Photorhabdus asymbiotica, Wang, X., Cheng, J., Shen, J., Liu, L., Li, N., Gao, N., Jiang, F., and Jin, Q., 2022
- Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides, Zhang, W., Li, Z., Sun, Y., Cui, P., Liang, J., Xing, Q., Wu, J., Xu, Y., Zhang, W., Zhang, Y., He, L., and Gao, N., 2022
- Transcription shapes DNA replication initiation to preserve genome integrity, Liu, Y., Ai, C., Gan, T., Wu, J., Jiang, Y., Liu, X., Lu, R., Gao, N., Li, Q., Ji, X., and Hu, J., 2021
- Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes, Zheng, L., Zheng, Z., Li, X., Wang, G., Zhang, K., Wei, P., Zhao, J., and Gao, N., 2021
- VHUT-cryo-FIB, a method to fabricate frozen hydrated lamellae from tissue specimens for in situ cryo-electron tomography, Zhang, J., Zhang, D., Sun, L., Ji, G., Huang, X., Niu, T., Xu, J., Ma, C., Zhu, Y., Gao, N., Xu, W., and Sun, F., 2021
- Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis, Zheng, L., Liu, Z., Wang, Y., Yang, F., Wang, J., Huang, W., Qin, J., Tian, M., Cai, X., Liu, X., Mo, X., Gao, N., and Jia, D., 2021
- Disome-seq reveals widespread ribosome collisions that promote cotranslational protein folding, Zhao, T., Chen, Y.M., Li, Y., Wang, J., Chen, S., Gao, N., and Qian, W., 2021
- Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy, Du, S., Cao, Y., Zhu, Q., Yu, P., Qi, F., Wang, G., Du, X., Bao, L., Deng, W., Zhu, H., Liu, J., Nie, J., Zheng, Y., Liang, H., Liu, R., Gong, S., Xu, H., Yisimayi, A., Lv, Q., Wang, B., He, R., Han, Y., Zhao, W., Bai, Y., Qu, Y., Gao, X., Ji, C., Wang, Q., Gao, N., Huang, W., Wang, Y., Xie, X.S., Su, X.D., Xiao, J., and Qin, C., 2020
- Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly, Micic, J., Li, Y., Wu, S., Wilson, D., Tutuncuoglu, B., Gao, N., and Woolford, J.L., Jr., 2020
- Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel, Wilson, D.M., Li, Y., LaPeruta, A., Gamalinda, M., Gao, N., and Woolford, J.L., Jr., 2020
- Structural snapshots of human pre-60S ribosomal particles before and after nuclear export, Liang, X., Zuo, M.Q., Zhang, Y., Li, N., Ma, C., Dong, M.Q., and Gao, N., 2020
- Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients` B Cells, Cao, Y., Su, B., Guo, X., Sun, W., Deng, Y., Bao, L., Zhu, Q., Zhang, X., Zheng, Y., Geng, C., Chai, X., He, R., Li, X., Lv, Q., Zhu, H., Deng, W., Xu, Y., Wang, Y., Qiao, L., Tan, Y., Song, L., Wang, G., Du, X., Gao, N., Liu, J., Xiao, J., Su, X.D., Du, Z., Feng, Y., Qin, C., Qin, C., Jin, R., and Xie, X.S., 2020
- Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation, Wang, W., Li, W., Ge, X., Yan, K., Mandava, C.S., Sanyal, S., and Gao, N., 2020
- Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin, Wang, Y., Wang, G., Li, Y., Zhu, Q., Shen, H., Gao, N., and Xiao, J., 2020
- Cooperative transport mechanism of human monocarboxylate transporter 2, Zhang, B., Jin, Q., Xu, L., Li, N., Meng, Y., Chang, S., Zheng, X., Wang, J., Chen, Y., Neculai, D., Gao, N., Zhang, X., Yang, F., Guo, J., and Ye, S., 2020
Awards
- 2019 Fourth Batch of National Talents Project, Technological Innovation Leading Talent
- 2018 Ministry of Science and Technology Middle and Young Age Science and Technology Innovation Leading Talent
- 2018 Ministry of Education Science Research Outstanding Achievement Award - Young Scientist Award
- 2017 Ministry of Education Distinguished Professor
- 2017 Tan Jiazhen Life Science Innovation Award
- 2017 National Natural Science Foundation of China Outstanding Young Scientist Fund
- 2016 Mao Yisheng Beijing Youth Science and Technology Award
- 2016 Zhongyuan Union Life Science Innovation Breakthrough Award
- 2016 WuXi AppTec Life Chemistry Scholar Award
- 2014 National Natural Science Foundation of China Excellent Young Scientist Fund
- 2013 Beijing Higher Education Young Talent Plan
- 2006 Distinguished Doctoral Dissertation Award, SUNY at Albany
