Professor | Chenjian Li | Asia Growth Partners

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Name	Chenjian Li
Contact Information	li_chenjian (AT) pku.edu.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Chenjian Li

Contact Information

li_chenjian (AT) pku.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Areas of Focus	Genetics Neurodegenerative Diseases Parkinson's Disease Mitochondrial Dysfunction Proteasome Dysfunction Synaptic Formation Neuronal Survival Mitophagy Mouse Models Genetic Rodent Models
Publications	Retake the Center Stage - New Development of Rat Genetics, Zheng, S., Geghman, K., Shenoy, S., Li, C, 2012 Proteasome dysfunction in animal models for PINK1 Parkinson’s disease, Yong Huang and Chenjian Li, 2012 Mouse Models for LRRk2 Parkinson’s Disease, Qing Xu, Sushila Shenoy and Chenjian Li, 2012 Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease, Dagda R, Gusdon A, Pien I, Strack S, C Li, Cherra J, and Chu C., 2011 Practical consideration of genetic rodent models for neurodegenerative disease, Kindiya Geghman and Chenjian Li, 2011 Pink1 regulates the assembly of oxidative phosphorylation machinery via mitochondrial fission, Wencheng Liu, Rebeca Acin-Perez, Kindiya Geghman, Giovanni Manfredi, Bing Wei Lu and Chenjian Li, 2011 PINK1-dependent recruitment of Parkin to mitochondria in mitophagy, Cristofol Vives-Bauza, Chun Zhou, Yong Huang, VAlina Dawson, Darren More, Grailhe, Ted Dawson, Chenjian Li, Serge Przedborski, 2010 Mutant PINK1 causes mitochondrial dysfunction, proteasomal deficit and α-synuclein aggregation in Parkinson’s disease models, Wencheng Liu, Cristofol Vives-Bauza, Rebeca Acin-Perez, Ai Yamamoto, Yingcai Tan, Yanping Li, Jordi Magrane, Mihaela Stavarache, Michael Kaplitt, Xin-Yun Huang, M. Flint Beal, Giovanni Manfredi and Chenjian Li, 2009 BAC transgenic mouse model for LRRK2 recapitulates robust Parkinson’s disease phenotypes, Yanping Li, Wencheng Liu, Tinmarlar F. Oo, Lei Wang, Yi Tang, Vernice Jackson-Lewis, Chun Zhou, Kindiya Geghman, Serge Przedborski, M.Flint Beal Robert Burke and Chenjian Li, 2009 MyD88-5 links mitochondra, microtubules and JNK3 in Neurons and regulates Neuronal survival, Younghwa Kim, Ping Zhou, Liping Qian, Jesica Lee, Chenjian Li, Constantino Iadecola, Carl Nathan and Aihao Ding, 2007 Leucine-rich repeat kinase 2: a New player with a familiar theme for Parkinson’s disease pathogenesis, Chenjian Li and M Flint Beal, 2005 Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis, Tsu-kang Sang, Chenjian Li, Lawrence Zipursky, George Jackson, 2005 Pathological cell-cell interactions elicited by a neuropathogenic form of mutant huntingtin contribute to cortical pathogenesis in HD mice, Xiaofeng Gu, Chenjian Li, Weicheng Wei, Victor Lo, Shiaoching Gong, Shihua Li, Takuji Iwasato, Shigeyoshi Itohara, XiaoJiang Li, Istvan Mody, Nathaniel Heintz, William Yang, 2005 Hippocampal neuron dendritic spine maturation, synaptic proteins immunoreactivity and performance in spatial learning tasks in mice, Chenjian Li, Wayne Brake, Russell Romeo, Marisa Gordon, Rodica Buzescu, Patrick Allen, Paul Greengard, Bruce McEwen, 2004 Highly Efficient Modification of Bacterial Artificial Chromosomes (BACs) Using Novel Shuttle Vectors Containing the R6Kr Origin of Replication, Shaoching Gong, William Yang, Chenjian Li, Nathaniel Heintz, 2002 Tracking the estrogen receptor in neurons: implications for estrogen-induced synapse formation, Bruce McEwen, Keith Akama, Steve Alves, Wayne Brake, Chenjian Li, Yuen G, 2001 Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites, Milner, T. A., McEwen, B. S., Hayashi, S., Chenjian Li, Reagan, L. P., Alves, S. E., 2001 InaF, a Protein Required For Transient Receptor Potential Ca2+ Channel Function, Chenjian Li, Chaoxian Geng, Hung-Tat Leung, Young Seok Hong, Lydia R. Strong, William L. Pak, 1999

Areas of Focus

Genetics
Neurodegenerative Diseases
Parkinson's Disease
Mitochondrial Dysfunction
Proteasome Dysfunction
Synaptic Formation
Neuronal Survival
Mitophagy
Mouse Models
Genetic Rodent Models

Publications

Retake the Center Stage - New Development of Rat Genetics, Zheng, S., Geghman, K., Shenoy, S., Li, C, 2012
Proteasome dysfunction in animal models for PINK1 Parkinson’s disease, Yong Huang and Chenjian Li, 2012
Mouse Models for LRRk2 Parkinson’s Disease, Qing Xu, Sushila Shenoy and Chenjian Li, 2012
Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease, Dagda R, Gusdon A, Pien I, Strack S, C Li, Cherra J, and Chu C., 2011
Practical consideration of genetic rodent models for neurodegenerative disease, Kindiya Geghman and Chenjian Li, 2011
Pink1 regulates the assembly of oxidative phosphorylation machinery via mitochondrial fission, Wencheng Liu, Rebeca Acin-Perez, Kindiya Geghman, Giovanni Manfredi, Bing Wei Lu and Chenjian Li, 2011
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy, Cristofol Vives-Bauza, Chun Zhou, Yong Huang, VAlina Dawson, Darren More, Grailhe, Ted Dawson, Chenjian Li, Serge Przedborski, 2010
Mutant PINK1 causes mitochondrial dysfunction, proteasomal deficit and α-synuclein aggregation in Parkinson’s disease models, Wencheng Liu, Cristofol Vives-Bauza, Rebeca Acin-Perez, Ai Yamamoto, Yingcai Tan, Yanping Li, Jordi Magrane, Mihaela Stavarache, Michael Kaplitt, Xin-Yun Huang, M. Flint Beal, Giovanni Manfredi and Chenjian Li, 2009
BAC transgenic mouse model for LRRK2 recapitulates robust Parkinson’s disease phenotypes, Yanping Li, Wencheng Liu, Tinmarlar F. Oo, Lei Wang, Yi Tang, Vernice Jackson-Lewis, Chun Zhou, Kindiya Geghman, Serge Przedborski, M.Flint Beal Robert Burke and Chenjian Li, 2009
MyD88-5 links mitochondra, microtubules and JNK3 in Neurons and regulates Neuronal survival, Younghwa Kim, Ping Zhou, Liping Qian, Jesica Lee, Chenjian Li, Constantino Iadecola, Carl Nathan and Aihao Ding, 2007
Leucine-rich repeat kinase 2: a New player with a familiar theme for Parkinson’s disease pathogenesis, Chenjian Li and M Flint Beal, 2005
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis, Tsu-kang Sang, Chenjian Li, Lawrence Zipursky, George Jackson, 2005
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant huntingtin contribute to cortical pathogenesis in HD mice, Xiaofeng Gu, Chenjian Li, Weicheng Wei, Victor Lo, Shiaoching Gong, Shihua Li, Takuji Iwasato, Shigeyoshi Itohara, XiaoJiang Li, Istvan Mody, Nathaniel Heintz, William Yang, 2005
Hippocampal neuron dendritic spine maturation, synaptic proteins immunoreactivity and performance in spatial learning tasks in mice, Chenjian Li, Wayne Brake, Russell Romeo, Marisa Gordon, Rodica Buzescu, Patrick Allen, Paul Greengard, Bruce McEwen, 2004
Highly Efficient Modification of Bacterial Artificial Chromosomes (BACs) Using Novel Shuttle Vectors Containing the R6Kr Origin of Replication, Shaoching Gong, William Yang, Chenjian Li, Nathaniel Heintz, 2002
Tracking the estrogen receptor in neurons: implications for estrogen-induced synapse formation, Bruce McEwen, Keith Akama, Steve Alves, Wayne Brake, Chenjian Li, Yuen G, 2001
Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites, Milner, T. A., McEwen, B. S., Hayashi, S., Chenjian Li, Reagan, L. P., Alves, S. E., 2001
InaF, a Protein Required For Transient Receptor Potential Ca2+ Channel Function, Chenjian Li, Chaoxian Geng, Hung-Tat Leung, Young Seok Hong, Lydia R. Strong, William L. Pak, 1999

Genetics Neurodegeneration Parkinson'S Mitochondria Proteasome Synapse Neurons Mitophagy Mouse Models Rodent Genetics

Yujun Hou - Tongji University

Lei Xue - Tongji University

Li Weidong - Shanghai Jiao Tong University

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