Professor | Bin Xia | Asia Growth Partners

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Name	Bin Xia
Contact Information	binxia(AT)pku.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Bin Xia

Contact Information

binxia(AT)pku.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	1991 - 1997 PhD in Biophysics, University of Wisconsin-Madison, USA 1985 - 1989 Bachelor of Science in Physiology and Biophysics, Peking University
Work Experience	2001 - Present Changjiang Distinguished Professor, Doctoral Supervisor in Biochemistry and Molecular Biology, School of Life Sciences, Peking University 1997 - 2001 Postdoctoral Researcher, The Scripps Research Institute, USA
Awards	Changjiang Scholar Award, Ministry of Education, 2001 Outstanding Youth Fund, National Natural Science Foundation of China, 2001

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

1991 - 1997 PhD in Biophysics, University of Wisconsin-Madison, USA
1985 - 1989 Bachelor of Science in Physiology and Biophysics, Peking University

Work Experience

2001 - Present Changjiang Distinguished Professor, Doctoral Supervisor in Biochemistry and Molecular Biology, School of Life Sciences, Peking University
1997 - 2001 Postdoctoral Researcher, The Scripps Research Institute, USA

Awards

Changjiang Scholar Award, Ministry of Education, 2001
Outstanding Youth Fund, National Natural Science Foundation of China, 2001

Areas of Focus	Nuclear Magnetic Resonance (NMR) technology in studying biomolecular structures and interactions
Publications	GapR binds DNA through dynamic opening of its tetrameric interface, Q. Huang, B. Duan, X. Dong, S. Fan, B. Xia, 2020 Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells, Y. Liao, B. Duan, Y. Zhang, X. Zhang, B. Xia, 2019 How Bacterial Xenogeneic Silencer Rok Distinguishes Foreign from Self DNA in Its Resident Genome, B. Duan, P. Ding, T. R. Hughes, W. W. Navarre, J. Liu, B. Xia, 2018 Zn(II) can mediate self-association of the extracellular C-terminal domain of CD147, S. Jin, P. Ding, P. Chu, H. Li, J. Sun, D. Liang, F. Song, B. Xia, 2018 CD147 functions as the signaling receptor for extracellular divalent copper in hepatocellular carcinoma cells, P. Ding, X. Zhang, S. Jin, B. Duan, P. Chu, Y. Zhang, Z. Chen, B. Xia, F. Song, 2017 Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy, Y. Kuang, K. Ma, C. Zhou, P. Ding, Y. Zhu, Q. Chen, B. Xia, 2016 A Novel AT-Rich DNA Recognition Mechanism for Bacterial Xenogeneic Silencer MvaT, P. Ding, K. A. McFarland, S. Jin, G. Tong, B. Duan, A. Yang, T. R. Hughes, J. Liu, S. L. Dove, W. W. Navarre, B. Xia, 2015 Foldon unfolding mediates the interconversion between Mpro-C monomer and 3D domain-swapped dimer, X. Kang, N. Zhong, P. Zou, S. Zhang, C. Jin, B. Xia, 2012 Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins, B. R.G. Gordon, Y Li, A. Coteb, M. T. Weirauch, P. Ding, T. R. Hughes, W. W. Navarre, B. Xia, and J. Liu, 2011 Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound Z18, S. Tian, J. Lin, J. Zhou, X. Wan, Y. Li, X. Ren, W. Yu, W. Zhong, J. Xiao, F. Sheng, Y. Chen, C. Jin, S. Li, Z. Zheng, and B. Xia, 2010 Lsr2 is A Nucleoid-Associated Protein that Targets AT-Rich Sequences and Virulence Genes in Mycobacterium tuberculosis, B. R.G. Gordon, Y. Li , L. Wang , A. Sintsova , H. V. Bakel , S. Tian, W. W. Navarre, B. Xia, and J. Liu, 2010 3D domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease, S. Zhang, N. Zhong, F. Xue, X. Kang, X. Ren, J. Chen, C. Jin, Z. Lou and B. Xia, 2010

Areas of Focus

Nuclear Magnetic Resonance (NMR) technology in studying biomolecular structures and interactions

Publications

GapR binds DNA through dynamic opening of its tetrameric interface, Q. Huang, B. Duan, X. Dong*, S. Fan*, B. Xia*, 2020
Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells, Y. Liao, B. Duan, Y. Zhang, X. Zhang, B. Xia*, 2019
How Bacterial Xenogeneic Silencer Rok Distinguishes Foreign from Self DNA in Its Resident Genome, B. Duan, P. Ding, T. R. Hughes, W. W. Navarre, J. Liu, B. Xia*, 2018
Zn(II) can mediate self-association of the extracellular C-terminal domain of CD147, S. Jin, P. Ding, P. Chu, H. Li, J. Sun, D. Liang, F. Song, B. Xia*, 2018
CD147 functions as the signaling receptor for extracellular divalent copper in hepatocellular carcinoma cells, P. Ding, X. Zhang, S. Jin, B. Duan, P. Chu, Y. Zhang, Z. Chen, B. Xia*, F. Song*, 2017
Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy, Y. Kuang, K. Ma, C. Zhou, P. Ding, Y. Zhu, Q. Chen, B. Xia*, 2016
A Novel AT-Rich DNA Recognition Mechanism for Bacterial Xenogeneic Silencer MvaT, P. Ding, K. A. McFarland, S. Jin, G. Tong, B. Duan, A. Yang, T. R. Hughes, J. Liu, S. L. Dove*, W. W. Navarre*, B. Xia*, 2015
Foldon unfolding mediates the interconversion between Mpro-C monomer and 3D domain-swapped dimer, X. Kang, N. Zhong, P. Zou, S. Zhang, C. Jin, B. Xia*, 2012
Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins, B. R.G. Gordon, Y Li, A. Coteb, M. T. Weirauch, P. Ding, T. R. Hughes, W. W. Navarre, B. Xia*, and J. Liu*, 2011
Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound Z18, S. Tian, J. Lin, J. Zhou, X. Wan, Y. Li, X. Ren, W. Yu, W. Zhong, J. Xiao, F. Sheng, Y. Chen, C. Jin, S. Li, Z. Zheng*, and B. Xia*, 2010
Lsr2 is A Nucleoid-Associated Protein that Targets AT-Rich Sequences and Virulence Genes in Mycobacterium tuberculosis, B. R.G. Gordon, Y. Li , L. Wang , A. Sintsova , H. V. Bakel , S. Tian, W. W. Navarre, B. Xia*, and J. Liu*, 2010
3D domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease, S. Zhang, N. Zhong, F. Xue, X. Kang, X. Ren, J. Chen, C. Jin, Z. Lou and B. Xia*, 2010

Nmr Biomolecules 3D Structure Molecular Biology Cell Biology Analytical Chemistry Protein Structure Dna Molecular Mechanisms Tumor Development

Haipeng Gong - Tsinghua University

Haipeng Gong - Tsinghua University

Wei Xie - Sun Yat-Sen University

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