Professor | Xiang Yu | Asia Growth Partners

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Name	Xiang Yu
Contact Information	{'en': 'Email: yuxiang01 (AT) pku.edu.cn', 'zh': '电子邮件：yuxiang01 (AT) pku.edu.cn', 'de': 'E-Mail: yuxiang01 (AT) pku.edu.cn'}
Language ability	English, Chinese
Province	Beijing

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Name

Xiang Yu

Contact Information

{'en': 'Email: yuxiang01 (AT) pku.edu.cn', 'zh': '电子邮件：yuxiang01 (AT) pku.edu.cn', 'de': 'E-Mail: yuxiang01 (AT) pku.edu.cn'}

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	1995-1999 PhD, University of Cambridge, MRC Laboratory of Molecular Biology (Cell Biology) 1992-1995 Bachelor, University of Cambridge, Trinity College (Natural Sciences)
Work Experience	2019-present Professor, Peking University College of Life Sciences 2019-present Researcher, Peking University-Tsinghua University Center for Life Sciences 2019-present Researcher, McGovern Institute for Brain Research at Peking University 2019-present Director, Autism Research Center, Peking University Health Science Center 2005-2019 Researcher, Institute of Neuroscience, Chinese Academy of Sciences 1999-2005 Postdoctoral Fellow, Stanford University Medical Center
Awards	2022 Chang Jiang Scholar Award 2020 North Brain Scholar 2019 Zhang Xiangtong Young Neuroscientist Award 2018 Leading Talent of the Ten Thousand Talents Plan 2017 Excellent Graduate Student Supervisor, Chinese Academy of Sciences 2017 Shanghai Leading Talent 2016 Shanghai Outstanding Academic Leader 2016 Young and Middle-aged Science and Technology Innovation Leader 2014 7th Shanghai Youth Science and Technology Talent (Basic Research) 2014 11th China Young Women Scientist Award 2012 Excellent Graduate Student Supervisor, Chinese Academy of Sciences 2011 National Outstanding Young Scientist Fund 2005 Hundred Talents Program, Chinese Academy of Sciences 2005 Grass Fellow, Marine Biological Laboratory, Woods Hole, MA 1999 Wellcome Prize Travelling Research Fellowship

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

1995-1999 PhD, University of Cambridge, MRC Laboratory of Molecular Biology (Cell Biology)
1992-1995 Bachelor, University of Cambridge, Trinity College (Natural Sciences)

Work Experience

2019-present Professor, Peking University College of Life Sciences
2019-present Researcher, Peking University-Tsinghua University Center for Life Sciences
2019-present Researcher, McGovern Institute for Brain Research at Peking University
2019-present Director, Autism Research Center, Peking University Health Science Center
2005-2019 Researcher, Institute of Neuroscience, Chinese Academy of Sciences
1999-2005 Postdoctoral Fellow, Stanford University Medical Center

Awards

2022 Chang Jiang Scholar Award
2020 North Brain Scholar
2019 Zhang Xiangtong Young Neuroscientist Award
2018 Leading Talent of the Ten Thousand Talents Plan
2017 Excellent Graduate Student Supervisor, Chinese Academy of Sciences
2017 Shanghai Leading Talent
2016 Shanghai Outstanding Academic Leader
2016 Young and Middle-aged Science and Technology Innovation Leader
2014 7th Shanghai Youth Science and Technology Talent (Basic Research)
2014 11th China Young Women Scientist Award
2012 Excellent Graduate Student Supervisor, Chinese Academy of Sciences
2011 National Outstanding Young Scientist Fund
2005 Hundred Talents Program, Chinese Academy of Sciences
2005 Grass Fellow, Marine Biological Laboratory, Woods Hole, MA
1999 Wellcome Prize Travelling Research Fellowship

Areas of Focus	Molecular mechanisms regulating neural circuit development and plasticity
Publications	Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions, Yu H., Miao W., Ji E., Huang S., Jin S., Zhu X., Liu M.Z., Sun Y.G., Xu F., and Yu X., 2022 Oxytocin Regulates Synaptic Transmission in the Sensory Cortices in a Developmentally Dynamic Manner, Zhang J., Li S.J., Miao W., Zhang X., Zheng J.J., Wang C., and Yu X., 2021 Q&A Xiang Yu, Yu X., 2021 Enriched environment rearing from birth reduced anxiety, improved learning and memory, and promoted social interactions in adult male mice, Zheng J.J., Zou R, Huang S, Song T.J, and Yu X., 2020 Retinoid X receptor α regulates DHA-dependent spinogenesis and functional synapse formation in vivo, Cao H., Li M., Li G., Wen B., Lu Y., and Yu X., 2020 Multiple morphological factors underlie experience-dependent cross-modal plasticity in the developing sensory cortices, Wang M., Yu Z., Li G., and Yu X., 2020 PDGFRβ cells rapidly relay inflammatory signal from the circulatory system to neurons via chemokine CCL2, Duan L., Zhang X.D., Miao W.Y., Sun Y.J., Xiong G., Wu Q., Li G., Yang P., Yu H., Li H., Wang Y., Zhang M., Hu L.Y., Tong X., Zhou W.H., and Yu X., 2018 Alterations in plasma cytokine levels in Chinese children with autism spectrum disorder, Hu C.C., Xu X., Xiong G.L., Xu Q., Zhou B.R., Li C.Y., Qin Q., Liu C.X., Li H.P., Sun Y.J., and Yu X., 2018 A critical role of presynaptic Cadherin/Catenin/p140cap complexes in stabilizing spines and functional synapses in the neocortex, Li M.Y., Miao W.Y., Wu Q.Z., He S.J., Yan G., Yang Y., Liu J.J., Taketo M.M. and Yu, X., 2017 CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development, Wang L., Li M.Y., Qu C., Miao W.Y., Yin Q, Liao J., Cao H.T., Huang M., Wang K., Zuo E., Peng G., Zhang S.X., Chen G., Li Q., Tang K., Yu Q., Li Z., Wong CCL, Xu G., Jing N., Yu X., and Li J., 2017 Distinct Defects in Spine Formation or Pruning in Two Gene Duplication Mouse Models of Autism, Wang M., Li H., Takumi T., Qiu Z., Xu X., Yu X., and Bian W.J., 2017 Recent Research Progress in Autism Spectrum Disorder, Yu X., Qiu Z., and Zhang D., 2017 Special issue on: 'Oxytocin in development and plasticity', Stoop R. and Yu X., 2017 Coordinated spine pruning and maturation mediated by inter-spine competition for cadherin/catenin complexes, Bian W.J., Miao W.Y., He S.J., Qiu Z. and Yu, X., 2015 Oxytocin mediates early experience–dependent cross-modal plasticity in the sensory cortices, Zheng J.J., Li S.J., Zhang X.D., Miao W.Y., Zhang D., Yao H. and Yu, X., 2014 Postsynaptic spiking homeostatically induces cell-autonomous regulation of inhibitory inputs via retrograde signaling, Peng Y.R., Zeng S.Y., Song H.L., Li M.Y., Yamada M.K., and Yu X., 2010 Early enriched environment promotes neonatal GABAergic neurotransmission and accelerates synapse maturation, He S., Ma J., Liu N. and Yu, X., 2010 N-cadherin dependent neuron-neuron interaction is required for the maintenance of activity-induced dendrite growth, Tan Z.J., Peng Y., Song H.L. and Yu X., 2010 Coordinated changes in dendritic arborization and synaptic strength during neural circuit development, Peng Y.R., He S., Marie H., Zeng S.Y., Ma J., Tan Z.J., Lee S., Malenka R.C., and Yu X., 2009 β-catenin is critical for dendritic morphogenesis, Yu X. and Malenka R.C., 2003

Areas of Focus

Molecular mechanisms regulating neural circuit development and plasticity

Publications

Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions, Yu H., Miao W., Ji E., Huang S., Jin S., Zhu X., Liu M.Z., Sun Y.G., Xu F., and Yu X., 2022
Oxytocin Regulates Synaptic Transmission in the Sensory Cortices in a Developmentally Dynamic Manner, Zhang J., Li S.J., Miao W., Zhang X., Zheng J.J., Wang C., and Yu X., 2021
Q&A Xiang Yu, Yu X., 2021
Enriched environment rearing from birth reduced anxiety, improved learning and memory, and promoted social interactions in adult male mice, Zheng J.J., Zou R, Huang S, Song T.J, and Yu X., 2020
Retinoid X receptor α regulates DHA-dependent spinogenesis and functional synapse formation in vivo, Cao H., Li M., Li G., Wen B., Lu Y., and Yu X., 2020
Multiple morphological factors underlie experience-dependent cross-modal plasticity in the developing sensory cortices, Wang M., Yu Z., Li G., and Yu X., 2020
PDGFRβ cells rapidly relay inflammatory signal from the circulatory system to neurons via chemokine CCL2, Duan L., Zhang X.D., Miao W.Y., Sun Y.J., Xiong G., Wu Q., Li G., Yang P., Yu H., Li H., Wang Y., Zhang M., Hu L.Y., Tong X., Zhou W.H., and Yu X., 2018
Alterations in plasma cytokine levels in Chinese children with autism spectrum disorder, Hu C.C., Xu X., Xiong G.L., Xu Q., Zhou B.R., Li C.Y., Qin Q., Liu C.X., Li H.P., Sun Y.J., and Yu X., 2018
A critical role of presynaptic Cadherin/Catenin/p140cap complexes in stabilizing spines and functional synapses in the neocortex, Li M.Y., Miao W.Y., Wu Q.Z., He S.J., Yan G., Yang Y., Liu J.J., Taketo M.M. and Yu, X., 2017
CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development, Wang L., Li M.Y., Qu C., Miao W.Y., Yin Q, Liao J., Cao H.T., Huang M., Wang K., Zuo E., Peng G., Zhang S.X., Chen G., Li Q., Tang K., Yu Q., Li Z., Wong CCL, Xu G., Jing N., Yu X., and Li J., 2017
Distinct Defects in Spine Formation or Pruning in Two Gene Duplication Mouse Models of Autism, Wang M., Li H., Takumi T., Qiu Z., Xu X., Yu X., and Bian W.J., 2017
Recent Research Progress in Autism Spectrum Disorder, Yu X., Qiu Z., and Zhang D., 2017
Special issue on: 'Oxytocin in development and plasticity', Stoop R. and Yu X., 2017
Coordinated spine pruning and maturation mediated by inter-spine competition for cadherin/catenin complexes, Bian W.J., Miao W.Y., He S.J., Qiu Z. and Yu, X., 2015
Oxytocin mediates early experience–dependent cross-modal plasticity in the sensory cortices, Zheng J.J., Li S.J., Zhang X.D., Miao W.Y., Zhang D., Yao H. and Yu, X., 2014
Postsynaptic spiking homeostatically induces cell-autonomous regulation of inhibitory inputs via retrograde signaling, Peng Y.R., Zeng S.Y., Song H.L., Li M.Y., Yamada M.K., and Yu X., 2010
Early enriched environment promotes neonatal GABAergic neurotransmission and accelerates synapse maturation, He S., Ma J., Liu N. and Yu, X., 2010
N-cadherin dependent neuron-neuron interaction is required for the maintenance of activity-induced dendrite growth, Tan Z.J., Peng Y., Song H.L. and Yu X., 2010
Coordinated changes in dendritic arborization and synaptic strength during neural circuit development, Peng Y.R., He S., Marie H., Zeng S.Y., Ma J., Tan Z.J., Lee S., Malenka R.C., and Yu X., 2009
β-catenin is critical for dendritic morphogenesis, Yu X. and Malenka R.C., 2003

Neural Development Neural Circuit Development Synaptic Plasticity Autism Autism Spectrum Disorders Sensory Experience Neuropeptides Oxytocin Neuroinflammation Dendritic Spine Maturation

Ma Ji - East China Normal University

Ji Ma - East China Normal University

Shuwen Zhang - University of Chinese Academy of Sciences

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