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Congling Xu
Life Science
Tongji University
Shanghai
Language: Chinese, English
Transcription
Regulation
Development
Mechanisms
Mammalian
Embryonic
Stem Cells
Differentiation
Pluripotency
Genomic Stability
Areas of Focus
- Transcriptional regulation mechanisms in higher biological developmental processes
- Transcriptional regulation mechanisms in mammalian early embryonic development
- Transcriptional regulation mechanisms in mammalian stem cell differentiation and pluripotency maintenance
Work Experience
- 2018 - Fudan University Affiliated Cancer Hospital - Postdoctoral Researcher
- 2023 - Tongji University School of Life Sciences and Technology - Distinguished Research Fellow, Dual-appointed Professor at Shanghai Fourth People's Hospital
Academic Background & Achievements
- 2018 - PhD in Science: Shanghai Jiao Tong University School of Medicine
- Received 'Super' Postdoctoral Award from Fudan University
Publications
- R-loop-dependent promoter-proximal termination ensures genome stability, Xu C, et al., 2023
- Stabilization of Integrator/INTAC by the small but versatile DSS1 protein, Xu C, et al., 2024
- From snapshots to a movie: Capturing eukaryotic transcription initiation at single-nucleotide resolution, Shang XY, Xu C, et al., 2024
- Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition, Fan P, Shang XY, Xu C, et al., 2024
- Mechanisms of SOSS-Integrator-PP2A complex in attenuating R-loops and promoting genome stability, Wang J, Xu C, et al., 2024
- SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape, Hu S, Xu C, et al., 2021
- Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase, Zheng H, Xu C, et al., 2020
- Synergy between arsenic trioxide and JQ1 on autophagy in pancreatic cancer, Xu C, et al., 2019
- Comprehensive epigenetic analyses reveal master regulators driving lung metastasis of breast cancer, Li K, Xu C, et al., 2019
- KDM3B suppresses APL progression by restricting chromatin accessibility and facilitating the ATRA-mediated degradation of PML/RARα, Wang X, Xu C, et al., 2019
- Cooperativity of co-factor NR2F2 with Pioneer Factors GATA3, FOXA1 in promoting ERα function, Jiang G, Xu C, et al., 2019
- Shared genetic and epigenetic mechanisms between chronic periodontitis and oral squamous cell carcinoma, Li S, Xu C, et al., 2018
Awards
- Outstanding Award from the Biophysical Society of China Women's Science Forum
