Professor | Xie Xin | Asia Growth Partners

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Name	Xie Xin
Contact Information	xiexin-2004@163.com
Language ability	English, Chinese
Province	Shanghai

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Name

Xie Xin

Contact Information

xiexin-2004@163.com

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	1996 - Bachelor of Science: Peking University, Chemistry 2002 - PhD: University of Medicine and Dentistry of New Jersey, Neuroscience Received support from the Chinese Academy of Sciences 'Hundred Talents Program' Supported by the Ministry of Education and Ministry of Human Resources
Work Experience	2004 - Present: National Center for Drug Screening, Head of Model Establishment II Department Postdoctoral Research: New Jersey Medical School, Neurobiology
Awards	National Candidate for the New Century Millions of Talents Project Outstanding Young Scientific and Technological Innovation Talent of the Shanghai Branch of the Chinese Academy of Sciences Shanghai Excellent Academic Leader Shanghai March 8th Red Banner Holder Expert with Special Government Allowance of the State Council 2013 - National Outstanding Young Female Scientist Award

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

1996 - Bachelor of Science: Peking University, Chemistry
2002 - PhD: University of Medicine and Dentistry of New Jersey, Neuroscience
Received support from the Chinese Academy of Sciences 'Hundred Talents Program'
Supported by the Ministry of Education and Ministry of Human Resources

Work Experience

2004 - Present: National Center for Drug Screening, Head of Model Establishment II Department
Postdoctoral Research: New Jersey Medical School, Neurobiology

Awards

National Candidate for the New Century Millions of Talents Project
Outstanding Young Scientific and Technological Innovation Talent of the Shanghai Branch of the Chinese Academy of Sciences
Shanghai Excellent Academic Leader
Shanghai March 8th Red Banner Holder
Expert with Special Government Allowance of the State Council
2013 - National Outstanding Young Female Scientist Award

Areas of Focus	G Protein-Coupled Receptor (GPCR) signaling pathways and major disease relevance research and new drug discovery Small molecule compounds regulating stem cell fate and new drug discovery
Publications	Small molecule compound induces chromatin de-condensation and facilitate induced pluripotent stem cell generation, Xiaoyuan Wei, Yueting Chen, Yongyu Xu, Yang Zan, Ru Zhang, Min Wang, Qiuhong Hua, Haifeng Gu, Fajun Nan, Xin Xie, 2014 Proliferation rate of somatic cells affects reprogramming efficiency, Yongyu Xu, Xiaoyuan Wei, Min Wang, Ru Zhang, Yanbin Fu, Mingzhe Xing, Qiuhong Hua, Xin Xie, 2013 Aurintricarboxylic Acid Ameliorates Experimental Autoimmune Encephalomyelitis by Blocking Chemokine-mediated Pathogenic Cell Migration and Infiltration, Feifei Zhang, Wei Wei, Hui Chai, Xin Xie, 2013 Blocking A2B Adenosine Receptor alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis via Inhibition of IL-6 Production and TH-17 Differentiation, Wei Wei, Changsheng Du, Jie Lv, Guixian Zhao, Zhenxin Li, Zhiying Wu, György Haskó, Xin Xie, 2013 Stress-mediated p38 activation promotes somatic cell reprogramming, Xinxiu Xu, Quan Wang, Yuan Long, Ru Zhang, Xiaoyuan Wei, Mingzhe Xing, Haifeng Gu, Xin Xie, 2013 The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis, Jie Lv, Changsheng Du, Wei Wei, Zhiying Wu, Guixian Zhao, Zhenxin Li, Xin Xie, 2012 G Protein-Coupled Receptors as Therapeutic Targets for Multiple Sclerosis, Chang-Sheng Du, Xin Xie, 2012 Novel object recognition as a facile behavior test for evaluating drug effects in AβPP/PS1 Alzheimer’s mouse model, Ru Zhang, Guizhen Xue, Shaodeng Wang, Lihong Zhang, Changjie Shi, Xin Xie, 2012 Antiasthmatic Drugs Targeting the Cysteinyl Leukotriene Receptor 1 Alleviate Central Nervous System Inflammatory Cell Infiltration and Pathogenesis of Experimental Autoimmune Encephalomyelitis, Liefeng Wang, Changsheng Du, Jie Lv, Wei Wei, Ye Cui, Xin Xie, 2011 Lithium, an anti-Psychotic Drug, Greatly Enhances the Generation of Induced Pluripotent Stem Cells, Quan Wang, Xinxiu Xu, Jun Li, Jing Liu, Haifeng Gu, Ru Zhang, Jiekai Chen, Yin Kuang, Jian Fei, Cong Jiang, Ping Wang, Duanqing Pei, Sheng Ding, Xin Xie, 2011 Intact Mdm2 E3 Ligase Activity Is Required for the Cytosolic Localization and Function of β-Arrestin2, Chenlei Yin, Ru Zhang, Yongyu Xu, Qiuyan Chen, Xin Xie, 2011 Bryostatin-5 blocks stromal cell-derived factor-1 induced chemotaxis via desensitization and down-regulation of cell surface CXCR4 receptors, He X, Fang L, Wang J, Yi Y, Zhang S, Xie X, 2008

Areas of Focus

G Protein-Coupled Receptor (GPCR) signaling pathways and major disease relevance research and new drug discovery
Small molecule compounds regulating stem cell fate and new drug discovery

Publications

Small molecule compound induces chromatin de-condensation and facilitate induced pluripotent stem cell generation, Xiaoyuan Wei, Yueting Chen, Yongyu Xu, Yang Zan, Ru Zhang, Min Wang, Qiuhong Hua, Haifeng Gu, Fajun Nan, Xin Xie, 2014
Proliferation rate of somatic cells affects reprogramming efficiency, Yongyu Xu, Xiaoyuan Wei, Min Wang, Ru Zhang, Yanbin Fu, Mingzhe Xing, Qiuhong Hua, Xin Xie, 2013
Aurintricarboxylic Acid Ameliorates Experimental Autoimmune Encephalomyelitis by Blocking Chemokine-mediated Pathogenic Cell Migration and Infiltration, Feifei Zhang, Wei Wei, Hui Chai, Xin Xie, 2013
Blocking A2B Adenosine Receptor alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis via Inhibition of IL-6 Production and TH-17 Differentiation, Wei Wei, Changsheng Du, Jie Lv, Guixian Zhao, Zhenxin Li, Zhiying Wu, György Haskó, Xin Xie, 2013
Stress-mediated p38 activation promotes somatic cell reprogramming, Xinxiu Xu, Quan Wang, Yuan Long, Ru Zhang, Xiaoyuan Wei, Mingzhe Xing, Haifeng Gu, Xin Xie, 2013
The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis, Jie Lv, Changsheng Du, Wei Wei, Zhiying Wu, Guixian Zhao, Zhenxin Li, Xin Xie, 2012
G Protein-Coupled Receptors as Therapeutic Targets for Multiple Sclerosis, Chang-Sheng Du, Xin Xie, 2012
Novel object recognition as a facile behavior test for evaluating drug effects in AβPP/PS1 Alzheimer’s mouse model, Ru Zhang, Guizhen Xue, Shaodeng Wang, Lihong Zhang, Changjie Shi, Xin Xie, 2012
Antiasthmatic Drugs Targeting the Cysteinyl Leukotriene Receptor 1 Alleviate Central Nervous System Inflammatory Cell Infiltration and Pathogenesis of Experimental Autoimmune Encephalomyelitis, Liefeng Wang, Changsheng Du, Jie Lv, Wei Wei, Ye Cui, Xin Xie, 2011
Lithium, an anti-Psychotic Drug, Greatly Enhances the Generation of Induced Pluripotent Stem Cells, Quan Wang, Xinxiu Xu, Jun Li, Jing Liu, Haifeng Gu, Ru Zhang, Jiekai Chen, Yin Kuang, Jian Fei, Cong Jiang, Ping Wang, Duanqing Pei, Sheng Ding, Xin Xie, 2011
Intact Mdm2 E3 Ligase Activity Is Required for the Cytosolic Localization and Function of β-Arrestin2, Chenlei Yin, Ru Zhang, Yongyu Xu, Qiuyan Chen, Xin Xie, 2011
Bryostatin-5 blocks stromal cell-derived factor-1 induced chemotaxis via desensitization and down-regulation of cell surface CXCR4 receptors, He X, Fang L, Wang J, Yi Y, Zhang S, Xie X, 2008

Gpcr Alzheimer'S Autoimmune Diseases Drug Discovery Stem Cells Ips Cells Neurodegeneration Cell Signaling Transgenic Models High-Throughput Screening

Lei Xue - Tongji University

Xie Xin - Tongji University

Ping Yo - Shanghai Jiao Tong University

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