Professor | Yu Yong | Asia Growth Partners

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Name	Yu Yong
Contact Information	yy3@tongji.edu.cn
Language ability	English, Chinese
Province	Shanghai

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Name

Yu Yong

Contact Information

yy3@tongji.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2006-2012 Joint PhD: Huazhong Agricultural University - University of Cambridge Identified key transcription factor Bcl11a regulating B cell development and hematopoietic stem cell maintenance
Work Experience	2019.04-present, Tongji University, School of Life Sciences and Technology, Professor 2018.02-present, Tongji University, Shanghai First Maternity and Infant Hospital, Researcher 2017.09-2019.04, Tongji University, School of Life Sciences and Technology, Distinguished Researcher 2013.02-2017.12, University of Cambridge Sanger Institute, Postdoctoral Researcher

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2006-2012 Joint PhD: Huazhong Agricultural University - University of Cambridge
Identified key transcription factor Bcl11a regulating B cell development and hematopoietic stem cell maintenance

Work Experience

2019.04-present, Tongji University, School of Life Sciences and Technology, Professor
2018.02-present, Tongji University, Shanghai First Maternity and Infant Hospital, Researcher
2017.09-2019.04, Tongji University, School of Life Sciences and Technology, Distinguished Researcher
2013.02-2017.12, University of Cambridge Sanger Institute, Postdoctoral Researcher

Areas of Focus	Development and functional regulation mechanisms of ILC2 cells High-throughput screening of new targets for tumor immunotherapy using CRISPR/Cas9 T cell regeneration and its mechanisms
Publications	Single-cell RNA-seq identifies a PD-1(hi) ILC progenitor and defines its development pathway, Yu Y et al., 2016 The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development, Yu Y et al., 2015

Areas of Focus

Development and functional regulation mechanisms of ILC2 cells
High-throughput screening of new targets for tumor immunotherapy using CRISPR/Cas9
T cell regeneration and its mechanisms

Publications

Single-cell RNA-seq identifies a PD-1(hi) ILC progenitor and defines its development pathway, Yu Y et al., 2016
The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development, Yu Y et al., 2015

Ilc2 Development Functional Regulation Mucosal Tissues Immune Regulation Metabolic Regulation Pathogen Infection Inflammatory Diseases Autoimmunity Cancer Crispr/Cas9 High-Throughput Screening Tumor Immunotherapy Pd-1 Ctla4 Monoclonal Antibodies T Cell Cytotoxicity Molecular Mechanisms T Cell Regeneration Adoptive Therapy Reprogramming Gene Editing Single-Cell Sequencing Gene Knockout Mice Humanized Mice

Youhai Chen - University of Chinese Academy of Sciences

Shun Li - University of Chinese Academy of Sciences

Xiang Zhao - University of Chinese Academy of Sciences

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