Professor | Rui Gao | Asia Growth Partners

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Name	Rui Gao
Contact Information	gaorui@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Rui Gao

Contact Information

gaorui@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2008.9—2012.7 Bachelor: Beijing Normal University, School of Life Sciences and Technology 2012.9—2017.6 PhD: Tsinghua University, School of Life Sciences, Beijing Institute of Life Sciences Published in international journals such as Cell Stem Cell, Developmental Cell, Cell Reports Medicine Hosted national and local scientific funding projects
Work Experience	2017.6—2020.5 - Tongji University, School of Life Sciences and Technology - Postdoctoral Researcher 2020.5—2023.12 - Tongji University, School of Life Sciences and Technology - Assistant Professor 2023.12—Present - Tongji University, School of Life Sciences and Technology - Associate Professor

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2008.9—2012.7 Bachelor: Beijing Normal University, School of Life Sciences and Technology
2012.9—2017.6 PhD: Tsinghua University, School of Life Sciences, Beijing Institute of Life Sciences
Published in international journals such as Cell Stem Cell, Developmental Cell, Cell Reports Medicine
Hosted national and local scientific funding projects

Work Experience

2017.6—2020.5 - Tongji University, School of Life Sciences and Technology - Postdoctoral Researcher
2020.5—2023.12 - Tongji University, School of Life Sciences and Technology - Assistant Professor
2023.12—Present - Tongji University, School of Life Sciences and Technology - Associate Professor

Areas of Focus	Regulatory mechanisms of key transcription factors in early mammalian embryonic development Epigenetic regulation mechanisms in the development of human primordial germ cells Molecular mechanisms of epigenetic defects and reprogramming induced by nuclear transplantation Establishment and optimization of single-cell and micro-epigenomic sequencing methods
Publications	Defining a TFAP2C-centered transcription factor network during murine peri-implantation, Gao Rui et al. Gonadal niche safeguards human fetal germline cell development following maternal SARS-CoV-2 infection, Gao Rui et al. ADNP modulates SINE B2-derived CTCF-binding sites during blastocyst formation in mice, Gao Rui et al., 2024 Resetting histone modifications during human prenatal germline development, Gao Rui et al., 2023 Transcriptome Dynamics and Cell Dialogs Between Oocytes and Granulosa Cells in Mouse Follicle Development, Gao Rui et al., 2023 Differential Transcriptomes and Methylomes of Trophoblast Stem Cells From Naturally-Fertilized and Somatic Cell Nuclear-Transferred Embryos, Gao Rui et al., 2021 Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs, Gao Rui et al., 2019 Inhibition of Aberrant DNA Re-methylation Improves Post-implantation Development of Somatic Cell Nuclear Transfer Embryos, Gao Rui et al., 2018 Direct induction of neural progenitor cells transiently passes through a partially reprogrammed state, Gao Rui et al., 2017 Progress in understanding epigenetic remodeling during induced pluripotency, Gao Rui et al., 2015

Areas of Focus

Regulatory mechanisms of key transcription factors in early mammalian embryonic development
Epigenetic regulation mechanisms in the development of human primordial germ cells
Molecular mechanisms of epigenetic defects and reprogramming induced by nuclear transplantation
Establishment and optimization of single-cell and micro-epigenomic sequencing methods

Publications

Defining a TFAP2C-centered transcription factor network during murine peri-implantation, Gao Rui et al.
Gonadal niche safeguards human fetal germline cell development following maternal SARS-CoV-2 infection, Gao Rui et al.
ADNP modulates SINE B2-derived CTCF-binding sites during blastocyst formation in mice, Gao Rui et al., 2024
Resetting histone modifications during human prenatal germline development, Gao Rui et al., 2023
Transcriptome Dynamics and Cell Dialogs Between Oocytes and Granulosa Cells in Mouse Follicle Development, Gao Rui et al., 2023
Differential Transcriptomes and Methylomes of Trophoblast Stem Cells From Naturally-Fertilized and Somatic Cell Nuclear-Transferred Embryos, Gao Rui et al., 2021
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs, Gao Rui et al., 2019
Inhibition of Aberrant DNA Re-methylation Improves Post-implantation Development of Somatic Cell Nuclear Transfer Embryos, Gao Rui et al., 2018
Direct induction of neural progenitor cells transiently passes through a partially reprogrammed state, Gao Rui et al., 2017
Progress in understanding epigenetic remodeling during induced pluripotency, Gao Rui et al., 2015

Transcription Factors Embryonic Development Epigenetics Germ Cells Nuclear Transplantation Reprogramming Single-Cell Sequencing Micro-Epigenomics Gene Editing Cell Fate

Shao Rong Gao - Tongji University

Xudong Guo - Tongji University

Jiang Cizhong - Tongji University

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