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Chong Li
Life Science
Tongji University
Shanghai
Language: English, Chinese, Japanese
Epigenetics
Embryo Development
Somatic Cell
Nuclear Transfer
Chromatin
Gene Activation
Transcription Factors
Nucleosome Organization
Zygotic Genome
Reprogramming
Areas of Focus
- Epigenetic regulation of early embryo development
- Epigenetic modification mechanisms in somatic cell nuclear transfer embryos
Work Experience
- 2010-04 to 2012-08 - RIKEN: Research Scientist
- From 2012-03 - Tongji University: Associate Researcher
Academic Background & Achievements
- 2001 - Bachelor's Degree: Shanghai Normal University
- 2007 - Master's Degree: Kansai Gakuin University
- 2010 - PhD: Kansai Gakuin University, joint training with RIKEN
- Significant original research results in early embryo development and somatic cell nuclear transfer
Publications
- Mechanical strain treatment improves nuclear transfer reprogramming efficiency by enhancing chromatin accessibility, Chen Y, Xu R, Zhou S, Zhao C, Hu Z, Hua Y, Xiong Y, Liu X, Lü J, Sun Y, Li C, Gao S, Zhang Y, 2023
- Two waves of H3K9me3 allocations ensure retrotransposon silencing in human preimplantation embryos, Xu R, Li S, Wu Q, Li C, Jiang M, Chen M, Yang L, Dong X, Wang H, Wang C, Liu X, Ou X, Gao S, 2022
- Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq, Yang L, Xu X, Xu R, Chen C, Zhang X, Chen M, Kou X, Zhao Y, Wang H, Liu X, Gao S, Li C, 2022
- Dynamic nucleosome organization after fertilization reveals regulatory factors for mouse zygotic genome activation, Wang C, Chen C, Liu X, Li C, Wu Q, Chen X, Yang L, Kou X, Zhao Y, Wang H, Gao Y, Zhang Y, Gao S, 2022
- Insights into epigenetic patterns in mammalian early embryos, Xu R, Li C, Liu X, Gao S, 2020
- Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos, Chen M, Zhu Q, Li C, Kou X, Zhao Y, Li Y, Xu R, Yang L, Yang L, Gu L, Wang H, Liu X, Jiang C, Gao S, 2020
- Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos, Liu X, Wang C, Liu W, Li J, Li C, Kou X, Chen J, Zhao Y, Gao H, Wang H, Zhang Y, Gao Y, Gao S, 2016
- Cloned mice from embryonic stem cells, Li C, Wakayama T, 2012
- Mouse Spermatozoa Preserved for Six Months Without Freezing Can Develop to Full Term, Li C, Mizutani E, Ono T, Terashita Y, Jia X-F, Shi H-J, Wakayama T, 2011
- An Efficient Method for Generating Transgenic Mice Using NaOH-treated Spermatozoa, Li C, Mizutani E, Ono T, Wakayama T, 2009
- Production of normal mice from spermatozoa denatured with high alkali treatment before ICSI, Li C, Mizutani E, Ono T, Wakayama T, 2009
Awards
- Best Posters Award (2016): Nuclear Transplantation and Cell Reprogramming International Symposium, Japan
- Outstanding Paper Award (2011): 13th Chinese Scholars Association in Japan, Nanjing
- Best Posters Award (2010): 9th International Transgenic Technology Conference, Berlin
- National Scholarship for Outstanding Self-financed Students (2009): Ministry of Education of the People's Republic of China, Beijing
- Nitta Memorial Award (2010): Kansai Gakuin University, Japan
