Areas of Focus
- Molecular mechanisms of cellular aging
- Role and mechanism of inflammatory aging in neurological diseases
- Alleviation and treatment of age-related neurodegenerative diseases
Work Experience
- 2009-2018 - Various research institutions including A*STAR Singapore and Howard Hughes Medical Institute: Postdoctoral Fellow, Research Associate
- 2020-present - Tongji University, First Maternity and Infant Health Hospital: Associate Researcher
Academic Background & Achievements
- 2002 - Bachelor's Degree: Nanjing University, School of Life Sciences
- 2005 - Master's Degree: Nanjing University, School of Life Sciences
- 2009 - PhD: Nanyang Technological University
- Selected for Shanghai 'Pujiang Talent' Plan in 2020
Publications
- A two-subpopulation model that reflects heterogeneity of large dense core vesicles in exocytosis, Qin N, Chen Z, Xue R*, 2022
- Activated or Impaired: An Overview of DNA Repair in Neurodegenerative Diseases, Qin N, Geng A, Xue R*, 2021
- The Role of Calmodulin vs. Synaptotagmin in Exocytosis, Xue R, Meng H, Yin J, Xia J, Hu Z, Liu H*, 2021
- Doc2-mediated superpriming supports synaptic augmentation, Xue R, Ruhl DA, Briguglio JS, Figueroa AG, Pearce RA, Chapman ER*, 2018
- Different states of synaptotagmin regulate evoked versus spontaneous release, Bai H#, Xue R, Bao H, Zhang L, Yethiraj A, Cui Q, Chapman ER*, 2016
- Structural elements that underlie Doc2 beta function during asynchronous synaptic transmission, Xue R, Gaffaney JD, Chapman ER*, 2015
- Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission, Liu H#, Bai H#, Xue R, Takahashi H, Edwardson JM, Chapman ER*, 2014
- Mutations that disrupt Ca2+-binding activity endow Doc2 beta with novel functional properties during synaptic transmission, Gaffaney JD#, Xue R, Chapman ER*, 2014
- Roles of Cholesterol in Vesicle Fusion and Motion, Zhang J#, Xue R, Ong W-Y, Chen P*, 2009
- PKC epsilon facilitates recovery of exocytosis after an exhausting stimulation, Xue R, Zhao Y, Su L, Ye F, Chen P*, 2009
- Involvement of PKC alpha in PMA-induced facilitation of exocytosis and vesicle fusion in PC12 cells, Xue R, Zhao Y, Chen P*, 2009
- Protective effects of ethyl docosahexaenoate on brain oxidative injury and edema induced by cerebral ischemic reperfusion, Xue R, Cao D, Zheng W, Sun L, Liu Z*, 2004