Professor | Le Rongrong | Asia Growth Partners

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Name	Le Rongrong
Contact Information	lerongrong@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Le Rongrong

Contact Information

lerongrong@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2008-2014: PhD in Life Sciences, China Agricultural University, Beijing Institute of Life Sciences Recipient of the National Natural Science Foundation of China Excellent Young Scientist Fund (2021) Recipient of the Shanghai Science and Technology Committee Young Scientist Star (A Category) (2021) Recipient of the Shanghai Morning Light Plan (2015)
Work Experience	2021.12-present: Tongji University, School of Life Sciences and Technology, Professor 2014.10-2021.12: Tongji University, School of Life Sciences and Technology, Assistant Professor
Awards	National Natural Science Foundation of China Excellent Young Scientist Fund (2021): Award for outstanding young scientists in natural sciences Shanghai Science and Technology Committee Young Scientist Star (A Category) (2021): Recognition for promising young scientists in technology fields Shanghai Morning Light Plan (2015): Support for talented researchers in early stages of their careers

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2008-2014: PhD in Life Sciences, China Agricultural University, Beijing Institute of Life Sciences
Recipient of the National Natural Science Foundation of China Excellent Young Scientist Fund (2021)
Recipient of the Shanghai Science and Technology Committee Young Scientist Star (A Category) (2021)
Recipient of the Shanghai Morning Light Plan (2015)

Work Experience

2021.12-present: Tongji University, School of Life Sciences and Technology, Professor
2014.10-2021.12: Tongji University, School of Life Sciences and Technology, Assistant Professor

Awards

National Natural Science Foundation of China Excellent Young Scientist Fund (2021): Award for outstanding young scientists in natural sciences
Shanghai Science and Technology Committee Young Scientist Star (A Category) (2021): Recognition for promising young scientists in technology fields
Shanghai Morning Light Plan (2015): Support for talented researchers in early stages of their careers

Areas of Focus	Molecular mechanisms of somatic cell reprogramming and stem cell aging Telomere regulation mechanisms in embryonic and somatic cell reprogramming Molecular mechanisms of adult stem cell aging
Publications	Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells, Le Rongrong, 2020 Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells, Le Rongrong, 2014 Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells, Le Rongrong, 2021 Lessons from expanded potential of embryonic stem cells: Moving toward totipotency, Le Rongrong, 2020 Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation, Le Rongrong, 2017 Enhanced Rejuvenation in Induced Pluripotent Stem Cell Derived Neurons Compared with Directly Converted Neurons from an Aged Mouse, Le Rongrong, 2015 High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells, Le Rongrong, 2017 Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs, Le Rongrong, 2017 DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development, Le Rongrong, 2018 Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b, Le Rongrong, 2018 Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development, Le Rongrong, 2018

Areas of Focus

Molecular mechanisms of somatic cell reprogramming and stem cell aging
Telomere regulation mechanisms in embryonic and somatic cell reprogramming
Molecular mechanisms of adult stem cell aging

Publications

Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells, Le Rongrong, 2020
Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells, Le Rongrong, 2014
Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells, Le Rongrong, 2021
Lessons from expanded potential of embryonic stem cells: Moving toward totipotency, Le Rongrong, 2020
Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation, Le Rongrong, 2017
Enhanced Rejuvenation in Induced Pluripotent Stem Cell Derived Neurons Compared with Directly Converted Neurons from an Aged Mouse, Le Rongrong, 2015
High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells, Le Rongrong, 2017
Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs, Le Rongrong, 2017
DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development, Le Rongrong, 2018
Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b, Le Rongrong, 2018
Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development, Le Rongrong, 2018

Somatic Cell Reprogramming Stem Cell Aging Molecular Mechanisms Telomere Regulation Embryonic Cell Reprogramming Adult Stem Cell Cellular Aging Telomere Maintenance Pluripotency Cellular Reprogramming

Renhao Xue - Tongji University

Renhao Xue - Tongji University

Xudong Guo - Tongji University

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