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Xudong Guo
Life Science
Tongji University
Shanghai
Language: Chinese, English
Epigenetics
Cell Fate
Stem Cells
Pluripotency
Myocardial Differentiation
Non-Coding Rna
Somatic Cell Reprogramming
Dna Damage
Cellular Reprogramming
Transcription Factors
Areas of Focus
- Epigenetic mechanisms in cell fate determination
- Stem cell pluripotency and myocardial differentiation
Work Experience
- 2016-2019 - Postdoctoral Researcher at Biomedical Engineering and Regenerative Medicine Research Institute, Tongji University
- Since February 2019 - Distinguished Researcher at the Advanced Research Institute for Translational Medicine, Tongji University
Academic Background & Achievements
- 2010 - Bachelor in Biotechnology: Tongji University
- 2016 - PhD in Biochemistry and Molecular Biology: Tongji University
- Published 30 SCI papers, including major journals like Cell Stem Cell and Nature Communications
Publications
- A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis, Guo Xudong et al., 2018
- microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming, Guo Xudong et al., 2013
- TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells, Guo Xudong et al., 2019
- Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation, Guo Xudong et al., 2013
- Cpmer: a new conserved eEF1A2-binding partner that regulates Eomes translation and cardiomyocyte differentiation, Guo Xudong et al., 2022
- Sin3a drives mesenchymal-to-epithelial transition through cooperating with Tet1 in somatic cell reprogramming, Guo Xudong et al., 2022
- lncNBAT1/APOBEC3A is a mediator of HBX-induced chemoresistance in diffuse large B-cell lymphoma cells, Guo Xudong et al., 2022
- LincRNA-1614 coordinates Sox2/PRC2-mediated repression of developmental genes in pluripotency maintenance, Guo Xudong et al., 2018
- HBV infection potentiates resistance to S-phase arrest-inducing chemotherapeutics by inhibiting CHK2 pathway in diffuse large B-cell lymphoma, Guo Xudong et al., 2018
- NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis, Guo Xudong et al., 2020
