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郭旭东
Life Science
同济大学
上海
Language: 中文, 英语
表观遗传学
细胞命运
干细胞
多能性
心肌分化
非编码Rna
体细胞重编程
Dna损伤
细胞重编程
转录因子
Areas of Focus
- 细胞命运决定中的表观遗传机制
- 干细胞多能性和心肌分化
Work Experience
- 2016-2019年 - 同济大学生物医学工程和再生医学研究所博士后
- 2019年2月起 - 同济大学转化医学高等研究院特聘研究员
Academic Background & Achievements
- 2010年 - 生物技术学士：同济大学
- 2016年 - 生物化学与分子生物学博士：同济大学
- 已发表SCI论文30篇，包括Cell Stem Cell和Nature Communications等重要期刊
Publications
- A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis, 郭旭东等, 2018
- microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming, 郭旭东等, 2013
- TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells, 郭旭东等, 2019
- Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation, 郭旭东等, 2013
- Cpmer: a new conserved eEF1A2-binding partner that regulates Eomes translation and cardiomyocyte differentiation, 郭旭东等, 2022
- Sin3a drives mesenchymal-to-epithelial transition through cooperating with Tet1 in somatic cell reprogramming, 郭旭东等, 2022
- lncNBAT1/APOBEC3A is a mediator of HBX-induced chemoresistance in diffuse large B-cell lymphoma cells, 郭旭东等, 2022
- LincRNA-1614 coordinates Sox2/PRC2-mediated repression of developmental genes in pluripotency maintenance, 郭旭东等, 2018
- HBV infection potentiates resistance to S-phase arrest-inducing chemotherapeutics by inhibiting CHK2 pathway in diffuse large B-cell lymphoma, 郭旭东等, 2018
- NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis, 郭旭东等, 2020
