Upload Avatar (500 x 500)
Zhaojun Zeng
Life Science
Central South University
Hunan
Language: Chinese, English
Gene Therapy
Tumor
Dna Repair
Dna Damage
Gene Structure
Molecular Mechanisms
Neuroblastoma
Breast Cancer
Cell Migration
Drug Resistance
Areas of Focus
- Human malignant tumor gene therapy
- DNA damage and repair
- Gene structure and function
Work Experience
- Current - Central South University, Department of Biochemistry and Molecular Biology, Director and Party Secretary
Academic Background & Achievements
- 2004 - PhD in Biochemistry and Molecular Biology
Publications
- The cell death and DNA damages caused by the Tet-On regulating HSV-tk/GCV suicide gene system in MCF-7 cells, Zeng ZJ, Xiang SG, Xue WW, Li HD, Ma N, Ren ZJ, Xu ZJ, Jiao CH, Wang CY, Hu WX, 2014
- TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival, Chavali PL, Saini RK, Zhai Q, Vizlin-Hodzic D, Venkatabalasubramanian S, Hayashi A, Johansson E, Zeng ZJ, Mohlin S, Påhlman S, Hansford L, Kaplan DR, Funa K, 2014
- TLX controls angiogenesis through interaction with the von Hippel-Lindau protein, Zhao-jun Zeng, Erik Johansson, Amiko Hayashi, Pavithra L. Chavali, Nina Akrap, Takeshi Yoshida, Kimitoshi Kohno, Hiroto Izumi, Keiko Funa, 2012
- TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors, Elmi M, Matsumoto Y, Zeng ZJ, Lakshminarasimhan P, Yang W, Uemura A, Nishikawa SI, Moshiri A, Tajima N, Agren H, Funa K, 2010
- Recombinant AAV-mediated HSVtk gene transfer with direct intratumoral injections and Tet-On regulation for implanted human breast cancer, Li ZB, Zeng ZJ, Chen Q, Luo SQ, Hu WX, 2006
- Retrovirus-mediated tk gene therapy of implanted human breast cancer in nude mice under the regulation of Tet-On, Hu WX, Zeng ZJ, Luo SQ, Chen Q, 2006
- Suicide gene therapy of human breast cancer in SCID mice model by the regulation of Tet-On, Hu WX, Zeng ZJ, Luo SQ, Chen Q, 2004
