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Zhengmao Hu
Life Science
Central South University
Hunan
Language: Chinese, English
Genetics
Pathogenic Genes
Human Diseases
Gene Identification
Functional Study
High Myopia
Autism
Children
Genetic Mechanisms
Research
Areas of Focus
- Identification and functional study of pathogenic genes in human genetic diseases
- Genetic mechanisms of high myopia
- Genetic mechanisms of autism in children
Work Experience
- 2019/01-Present - Vice Dean, School of Life Sciences, Central South University
- 2016/10-Present - Researcher, Central South University/Medical Genetics Research Center
- 2012/12-2013/12 - Visiting Scholar, University of Illinois at Chicago
- 2010/10-2016/09 - Associate Researcher, Central South University/National Key Laboratory of Medical Genetics
- 2007/07-2010/09 - Assistant Researcher, Central South University
- 1994/07-2001/08 - Intern Researcher/Assistant Researcher, Hunan Edible Mushroom Research Institute
Academic Background & Achievements
- 2004/09-2007/07 PhD in Genetics, Central South University/National Key Laboratory of Medical Genetics
- 2001/09-2004/07 Master's in Genetics, Central South University/National Key Laboratory of Medical Genetics
- 1990/09-1994/07 Bachelor's in Biology, Hunan Normal University
Publications
- Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2, Jiang Y, Peng Y, Tian Q, Cheng Z, Feng B, Hu J, Xia L, Guo H, Xia K, Zhou L, Hu Z, 2024
- CCDC66 mutations are associated with high myopia through affected cell mitosis, Chen X, Tong P, Jiang Y, Cheng Z, Zang L, Yang Z, Lan W, Xia K, Hu Z, Tian Q, 2024
- GLRA2 gene mutations cause high myopia in humans and mice, Tian Q, Tong P, Chen G, Deng M, Cai T, Tian R, Zhang Z, Xia K, Hu Z, 2023
- Case series of congenital pseudarthrosis of the tibia unfulfilling neurofibromatosis type 1 diagnosis: 21% with somatic NF1 haploinsufficiency in the periosteum, Zheng Y, Zhu G, Liu Y, Zhao W, Yang Y, Luo Z, Fu Y, Mei H, Hu Z, 2022
- The autism risk gene CNTN4 modulates dendritic spine formation, Zhao R, Zhu T, Liu Q, Tian Q, Wang M, Chen J, Tong D, Yu B, Guo H, Xia K, Qiu Z, Hu Z, 2021
- Biallelic loss-of-function variants in NEMF cause central nervous system impairment and axonal polyneuropathy, Ahmed A, Wang M, Bergant G, Maroofian R, Zhao R, Alfadhel M, Nashabat M, AlRifai MT, Eyaid W, Alswaid A, Beetz C, Qin Y, Zhu T, Tian Q, Xia L, Wu H, Shen L, Dong S, Yang X, Liu C, Ma L, Zhang Q, Khan R, Shah AA, Guo J, Tang B, Leonardis L, Writzl K, Peterlin B, Guo H, Malik S, Xia K, Hu Z, 2021
- AKAP2 identified as a novel gene mutated in a Chinese family with adolescent idiopathic scoliosis, Li W, Li Y, Zhang L, Guo H, Tian D, Peng Y, Zheng Y, Dai Y, Xia K, Lan X, Wang B, Hu Z, 2016
- Mutations of P4HA2 encoding prolyl 4-hydroxylase 2 are associated with nonsyndromic high myopia, Guo H, Tong P, Liu Y, Xia L, Wang T, Tian Q, Li Y, Hu Y, Zheng Y, Jin X, Xiong W, Tang B, Feng Y, Li J, Pan Q, Hu Z, Xia K, 2015
- Common genetic variants on 1p13.2 associate with risk of autism, Xia K, Guo H, Hu Z, Xun G, Zuo L, Peng Y, Wang K, He Y, Xiong Z, Sun L, Pan Q, Long Z, Zou X, Li X, Li W, Xu X, Lu L, Liu Y, Hu Y, Tian D, Long L, Ou J, Zhang L, Pan Y, Chen J, Peng H, Liu Q, Luo X, Su W, Wu L, Liang D, Dai H, Yan X, Feng Y, Tang B, Li J, Miedzybrodzka Z, Xia J, Zhang Z, Zhang X, St Clair D, Zhao J, Zhang F, 2014
- SLC39A5 mutations interfering with the BMP/TGF-beta pathway in non-syndromic high myopia, Guo H, Jin X, Zhu T, Wang T, Tong P, Tian L, Peng Y, Sun L, Wan A, Chen J, Liu Y, Li Y, Tian Q, Xia L, Zhang L, Pan Y, Lu L, Liu Q, Shen L, Xiong W, Li J, Tang B, Feng Y, Zhang X, Zhang Z, Pan Q, Hu Z, Xia K, 2014
Awards
- 2019: Second Prize in Natural Science, Ministry of Education
