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Lei Han
Medical School
Wuhan University
Hubei
Language: Chinese, English
Transmembrane
Transport Proteins
Drug Development
Substrate Transport
Protein Conformation
Membrane Potential
Metabolic Transport
Disease Relation
Structural Biology
High-Throughput Screening
Areas of Focus
- Mechanisms of transmembrane transport proteins and drug development
- Important metabolic transport proteins related to major diseases
Work Experience
- 2017.08--2023.10 Postdoctoral Researcher, Department of Molecular and Cellular Physiology, Stanford University
- 2023.11--Present Professor, Basic Medical College of Wuhan University, PI at Taikang Life Medical Center
Academic Background & Achievements
- 2005.09--2009.06 Bachelor in Bioengineering, Beijing University of Chemical Technology
- 2009.09--2012.06 Master in Biochemistry and Molecular Biology, Chinese Academy of Agricultural Sciences
- 2012.09--2017.06 PhD in Biochemistry and Molecular Biology, Institute of Biophysics, Chinese Academy of Sciences
Publications
- Structure and mechanism of the alkane-oxidizing enzyme AlkB, Xue Guo, Jianxiu Zhang, Lei Han, Juliet Lee, Shoshana C Williams, Allison Forsberg, Yan Xu, Rachel Narehood Austin, Liang Feng, 2023
- Structure and mechanism of the SGLT family of glucose transporters, Lei Han, Qianhui Qu, Deniz Aydin, Ouliana Panova, Michael J Robertson, Yan Xu, Ron O Dror, Georgios Skiniotis, Liang Feng, 2022
- Molecular mechanism of substrate recognition and transport by the AtSWEET13 sugar transporter, Lei Han, Yongping Zhu, Min Liu, Ye Zhou, Guangyuan Lu, Lan Lan, Xianping Wang, Yongfang Zhao, Xuejun C Zhang, 2017
Awards
- 2019: Dean's Postdoctoral Fellowship, School of Medicine, Stanford University
- National Talent Program Awardee
