Areas of Focus
- Neuroimmunology
- Pathogenesis and treatment of autoimmune diseases of the nervous system
- Design and screening of biologically active peptides targeting potassium channels
- Preclinical research on peptide therapeutics for neuroimmune diseases
Work Experience
- 2008.09-2011.03 Postdoctoral Researcher, Wuhan University
- 2011.04-2016.12 Lecturer, Wuhan University
- 2017.01-present Associate Professor, Wuhan University
Academic Background & Achievements
- 1999-2003 Bachelor in Biotechnology, Wuhan University
- 2003-2008 PhD in Microbiology, Wuhan University
Publications
- Inhibition of DPP4 enhances inhibitory synaptic transmission through activating the GLP-1/GLP-1R signaling pathway in a rat model of febrile seizures, Zhang Y, Liu Y, Xu J, Sun Q, Yu F, Cheng J, Peng B, Liu W, Xiao Z, Yin J, Han S*, He X, 2018
- A Kv1.3 channel-specific blocker alleviates neurological impairment through inhibiting T-cell activation in experimental autoimmune encephalomyelitis, Yuan XL, Zhao YP, Huang J, Liu JC, Mao WQ, Yin J, Peng BW, Liu WH, Han S*, He XH*, 2018
- Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis, Huang J., Han S., Sun Q., Zhao Y., Liu J., Yuan X., Mao W., Peng B., Liu W., Yin J., He X., 2017
- Decreased methylation level of H3K27me3 increases seizure susceptibility, Zhongcheng Wang, Yusong Zhang, Jian Fang, Fang Yu, Duanhe Heng, Yuanteng Fan, Jian Xu, Biwen Peng, Wanhong Liu, Song Han*, Xiaohua He*, 2016
- Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues, Zongyun Chen, Youtian Hu, Jun Hu, Weishan Yang, Jean-Marc Sabatier, Michel De Waard, Zhijian Cao, Wenxin Li, Song Han*, Yingliang Wu*, 2014
- Astragalus polysaccharide induces anti-inflammatory effects dependent on AMPK activity in palmitate-treated RAW264.7 cells, Jinzhi Lu, Xiong Chen, Yingying Zhang, Jian Xu, Lianglu Zhang, Zhi Li, Wanhong Liu, Jingping Ouyang, Song Han*, Xiaohua He*, 2013
- Expression and characterization of a novel scorpine-like peptide Ev37, from the scorpion Chaerilus tricostatus, Jing Feng, Congya Yua, Mingyu Wang, Zhi Li, Yingliang Wu, Zhijian Cao, Wenxin Li, Xiaohua He, Song Han*, 2013