Areas of Focus
- Immunology - Major Diseases Related to Inflammation
Work Experience
- 2007-10~Present - Institute of Nutrition and Health - Researcher
- 2005-07~2007-08 - Cleveland Clinic Foundation, USA - Research Assistant Professor
- 2003-07~2005-07 - Cleveland Clinic Foundation, USA - Research Staff
- 2000-07~2003-07 - Cleveland Clinic Foundation, USA - Postdoctoral Fellow
- 1996-09~1999-08 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - PhD
- 1990-09~1996-09 - Yangzhou Pharmaceutical Research Institute - Engineer
- 1987-09~1990-06 - Nanjing Normal University - Master's
- 1983-09~1987-07 - Nanjing Normal University - Bachelor's
Academic Background & Achievements
- 1996-09--1999-08 PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 1987-09--1990-06 Master's: Nanjing Normal University
- 1983-09--1987-07 Bachelor's: Nanjing Normal University
Publications
- Triggering endogenous Z-RNA sensing for antitumor therapy through ZBP1-dependent necroptosis, Qian Youcun, 2023
- The impact of lung microbiota dysbiosis on inflammation, Qian Youcun, 2020
- Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing, Qian Youcun, 2019
- Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection, Qian Youcun, 2019
- Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles, Qian Youcun, 2019
- Antigen-specific CD8t T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, Qian Youcun, 2017
- FGF2 cooperates with IL-17 to promote autoimmune inflammation, Qian Youcun, 2017
- Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, Qian Youcun, 2015
- Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis, Qian Youcun, 2014
- Peli1 sets the CNS on fire, Qian Youcun, 2013
- IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases, Qian Youcun, 2013
- The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-��., Qian Youcun, 2012
- TRAF6 dependent Act1 phosphorylation by the IKK-related kinases suppresses IL-17-induced NF-��B activation, Qian Youcun, 2012
- NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens, Qian Youcun, 2012
- Persistent Stimulation with Interleukin-17 Desensitizes Cells through SCF-TrCP���Mediated Degradation of Act1, Qian Youcun, 2011
- IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens, Qian Youcun, 2011
- TRAF3通过抑制白介素-17受体信号转导调控自身免疫脑脊髓炎, Qian Youcun, 2010
- The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease, Qian Youcun, 2007
- Act1, a Negative Regulator in CD40- and BAFF-Mediated B Cell Survival, Qian Youcun, 2004
- The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity, Qian Youcun
Awards
- Excellent Graduate Student Supervisor (2015): Institute Level
- Excellent Mentor (2014): Institute Level
- Excellent Graduate Student Supervisor (2013): Institute Level
- **** Final Evaluation Excellent (2012): Institute Level
- State Council Special Allowance (2012): Ministry Level
- Chinese Academy of Sciences **** (2008): Institute Level
- Shanghai Pujiang Talent Program (2008): Municipal Level
- Leukemia & Lymphoma Society Special Research Grant (2006): Other
- International Society for Interferon and Cytokine Research Young Investigator Award (2005): Other
- International Cytokine Society Postdoctoral Award (2004): Other