Areas of Focus
- Design, synthesis, and development of antitumor and antiviral drugs
- Cell-specific molecular regulation mechanisms of estrogen receptors and novel SERMs, SERDs, and PROTACs
- Diversity-oriented synthesis and rational drug design in chemical biology and drug discovery
Work Experience
- 2007/12 - Present: Professor, Doctoral Supervisor at Wuhan University School of Pharmacy
- 2003/12 - 2007/11: Postdoctoral Researcher at University of Illinois at Urbana-Champaign
- 2001/09 - 2003/12: Postdoctoral Researcher at University of Ottawa
- 1997/09 - 2000/07: PhD Student in Organic Chemistry, Sichuan University
Academic Background & Achievements
- 2007/12 - Present: Professor, Doctoral Supervisor at Wuhan University School of Pharmacy
- 2003/12 - 2007/11: Postdoctoral Researcher at University of Illinois at Urbana-Champaign, USA
- 2001/09 - 2003/12: Postdoctoral Researcher at University of Ottawa, Canada
- 1997/09 - 2000/07: PhD in Organic Chemistry, Sichuan University
- 1994/09 - 1997/07: Master's in Organic Chemistry, Sichuan University
- 1990/09 - 1994/07: Bachelor's in Chemistry, Yan'an University
Publications
- Discovery of Novel Bicyclic Phenylselenyl-Containing Hybrids: An Orally Bioavailable, Potential and Multi-acting Class of Estrogen Receptor Modulators against Endocrine-Resistant Breast Cancer, Xiangping Deng, Baohua Xie, Qiuzi Li, Yuan Xiao, Zhiye Hu, Xiaofei Deng, Pingping Fang, Chune Dong, Hai-Bing Zhou, Jian Huang, 2022
- Discovery of Aryl Benzoyl Hydrazide Derivatives as Novel Potent Broad-Spectrum Inhibitors of Influenza A Virus RNA Dependent RNA Polymerase (RdRp), Xinjin Liu, Jinsen Liang, Yongshi Yu, Xin Han, Lei Yu, Feifei Chen, Zhichao Xu, Qi Chen, Mengyu Jin, Chune Dong, Hai-Bing Zhou, Ke Lan, Shuwen Wu, 2022
Awards
- 2021: Second Prize of Hubei Province Science and Technology Progress Award (Third Contributor)
- 2020-2021: Wuhan University Undergraduate Excellent Teaching Performance Award
- 2016: Third Prize of Hubei Province Natural Science Award (First Contributor)
- 2013: First Hubei Province Medical Leading Talent
- 2012: Distinguished Professor of Wuhan University
- 2010: WuXi AppTec Life Science and Chemistry Research Award
- 2009: Ministry of Education New Century Excellent Talents