Areas of Focus
- Drug Chemistry
- Organic Synthesis
Work Experience
- 2018-06~2021-02 - Baylor College of Medicine - Postdoctoral Researcher
- 2017-08~2018-06 - H. Lee Moffitt Cancer Center and Research Institute - Postdoctoral Researcher
Academic Background & Achievements
- 2012-09--2017-07 PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 2008-09--2012-06 Bachelor's: Sichuan University
Publications
- Design, synthesis and biological evaluation of pyrazolo3,4-dpyridazinone derivatives as covalent FGFR inhibitors, Xiaowei Wu, Mengdi Dai, Rongrong Cui, Yulan Wang, Chunpu Li, Xia Peng, Jihui Zhao, Bao Wang, Yang Dai, Dan Feng, Tianbiao Yang, Hualiang Jiang, Meiyu Geng, Jing Ai, Mingyue Zheng, Hong Liu, 2021
- Additive-Controlled Divergent Synthesis of Tetrasubstituted 1,3-Enynes and Alkynylated 3H-Pyrrolo1,2-aindol-3-ones via Rhodium Catalysis, Zhao, Fei, Gong, Xin, Lu, Yangbin, Qiao, Jin, Jia, Xiuwen, Ni, Hangcheng, Wu, Xiaowei, Zhang, Xiaoning, 2021
- Design, Synthesis and pharmacological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors, Wu Xiaowei, 2021
- Rhodium(III)-Catalyzed C-H Alkenylation/Directing Group Migration for the Regio- and Stereoselective Synthesis of Tetrasubstituted Alkenes, Wu, Xiaowei, Lu, Yangbin, Qiao, Jin, Dai, Wenhao, Jia, Xiuwen, Ni, Hangcheng, Zhang, Xiaoning, Liu, Hong, Zhao, Fei, 2020
- Ruthenium-Catalyzed C–H Allylation of Alkenes with Allyl Alcohols via C–H Bond Activation in Aqueous Solution, Wu Xiaowei, Haitao Ji, 2020
- Synthesis of Indole-Fused Polyheterocycles via Rh(III)-Catalyzed Regioselective [4+2] Annulation/Lactonization of Indoles with 4-Hydroxy-2-Alkynoates, Wu Xiaowei, 2020
- Discovery and Development of a Series of Pyrazolo3,4-dpyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design, Wang, Yulan, Dai, Yang, Wu, Xiaowei, Li, Fei, Liu, Bo, Li, Chunpu, Liu, Qiufeng, Zhou, Yuanyang, Wang, Bao, Zhu, Mingrui, Cui, Rongrong, Tan, Xiaoqin, Xiong, Zhaoping, Liu, Jia, Tan, Minjia, Xu, Yechun, Geng, Meiyu, Jiang, Hualiang, Liu, Hong, Ai, Jing, Zheng, Mingyue, 2019
- The Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as Novel Covalent FGFR Inhibitors by Rational Drug Design, Wu Xiaowei, 2019
- Regio-selective and stereo-selective hydrosilylation of internal alkynes catalyzed by ruthenium complexes, Dai, Wenhao, Wu, Xiaowei, Li, Chunpu, Zhang, Rui, Wang, Jiang, Liu, Hong, 2018
- Rhodium(III)-catalyzed C-H allylation of indoles with allyl alcohols via beta-hydroxide elimination, Wu, Xiaowei, Ji, Haitao, 2018
- 先导化合物结构优化策略（六）——改善化合物血浆稳定性, 吴小伟, 王江, 柳红, 2018
- Ruthenium(II)-Catalyzed Regio- and Stereoselective C-H Allylation of Indoles with Allyl Alcohols, Wu, Xiaowei, Ji, Haitao, 2018
- Rhodium-Catalyzed [4 + 1] Cyclization via C-H Activation for Divergent Heterocycle Bearing a Quaternary Carbon Synthesis, Wu Xiaowei, 2018
- Propargyl alcohols as one-carbon synthons: redox-neutral Rh (III)-catalyzed C-H bond activation for the synthesis of isoindolinones bearing a quaternary carbon, Wu Xiaowei, 2017
- Propargyl Alcohols as One-Carbon Synthons: Redox-Neutral Rhodium(III)-Catalyzed C-H Bond Activation for the Synthesis of Isoindolinones Bearing a Quaternary Carbon, Wu, Xiaowei, Wang, Bao, Zhou, Yu, Liu, Hong, 2017
- Ruthenium-Catalyzed Redox-Neutral 4+1 Annulation of Benzamides and Propargyl Alcohols via C-H Bond Activation, Wu, Xiaowei, Wang, Bao, Zhou, Shengbin, Zhou, Yu, Liu, Hong, 2017
- Ruthenium(II)-Catalyzed Redox-Neutral 3+2 Annulation of Indoles with Internal Alkynes via C-H Bond Activation: Accessing a Pyrroloindolone Scaffold, Xie, Yanan, Wu, Xiaowei, Li, Chunpu, Wang, Jiang, Li, Jian, Liu, Hong, 2017
- Site-specific indolation of proline-based peptides via copper(II)-catalyzed oxidative coupling of tertiary amine N-oxides, Wu, Xiaowei, Zhang, Dengyou, Zhou, Shengbin, Gao, Feng, Liu, Hong, 2015
- Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors, Yang, Wei, Li, Lixuan, Wang, Yulan, Wu, Xiaowei, Li, Tingting, Yang, Nan, Su, Mingbo, Sheng, Li, Zheng, Mingyue, Zang, Yi, Li, Jia, Liu, Hong, 2015
- Design, synthesis and biological evaluation of 4-anilinothieno2,3-dpyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors, Yang, Wei, Li, Lixuan, Ji, Xun, Wu, Xiaowei, Su, Mingbo, Sheng, Li, Zang, Yi, Li, Jia, Liu, Hong, 2014
