Professor | Wanyi Tai | Asia Growth Partners

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Name	Wanyi Tai
Contact Information	wanyi-tai@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Wanyi Tai

Contact Information

wanyi-tai@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2000.09 - 2004.07 Bachelor in Traditional Chinese Pharmacy, China Pharmaceutical University 2004.09 - 2007.07 Master in Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences 2007.08 - 2012.08 PhD in Pharmaceutics, University of Missouri-Kansas City
Work Experience	2012.09 - 2013.11 Postdoctoral Researcher, Department of Biomedical Engineering, University of North Carolina at Chapel Hill 2013.12 - 2018.12 Postdoctoral Researcher, Department of Bioengineering, University of Washington 2019.02 - 2020.11 Distinguished Research Fellow, School of Pharmaceutical Sciences, Wuhan University 2020.12 - present Professor, School of Pharmaceutical Sciences, Wuhan University

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2000.09 - 2004.07 Bachelor in Traditional Chinese Pharmacy, China Pharmaceutical University
2004.09 - 2007.07 Master in Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2007.08 - 2012.08 PhD in Pharmaceutics, University of Missouri-Kansas City

Work Experience

2012.09 - 2013.11 Postdoctoral Researcher, Department of Biomedical Engineering, University of North Carolina at Chapel Hill
2013.12 - 2018.12 Postdoctoral Researcher, Department of Bioengineering, University of Washington
2019.02 - 2020.11 Distinguished Research Fellow, School of Pharmaceutical Sciences, Wuhan University
2020.12 - present Professor, School of Pharmaceutical Sciences, Wuhan University

Areas of Focus	Pharmaceutics Antibody Engineering Biopharmaceutical Drug Delivery
Publications	Insight into the siRNA transmembrane delivery — from cholesterol conjugating to tagging., Yan Zheng, Wanyi Tai, 2019 Current aspects of siRNA bioconjugate for in vitro and in vivo delivery., Wanyi Tai, 2019 Chemical Modulation of siRNA lipophilicity for efficient delivery., Wanyi Tai, 2019 Cytosolic delivery of proteins by cholesterol tagging., Wanyi Tai#, Pengfei Zhao#, Xiaohu Gao, 2020 Silencing ribonucleoprotein: a biomimetic platform for targeted siRNA delivery., Wanyi Tai, Xiaohu Gao, 2019 Synthetic polymer tag for intracellular delivery of siRNA., Wanyi Tai, Xiaohu Gao, 2018 A ribonucleoprotein octamer for targeted siRNA delivery., Wanyi Tai, Junwei Li, Eva Corey, Xiaohu Gao, 2018 Noncovalent tagging of siRNA with steroids for transmembrane delivery., Wanyi Tai, Xiaohu Gao, 2018 Functional peptides for siRNA delivery., Wanyi Tai, Xiaohu Gao, 2017 Bio-inspired nanovesicles for glucose-responsive release of insulin., Wanyi Tai, Ran Mo, Jin Di, Vinayak Subramanian, Xiao Gu, Zhen Gu, 2014 Folding graft copolymer with pendant drug segment for co-delivery of anticancer drugs., Wanyi Tai#, Ran Mo#, Yue Lu, Tianyue Jiang, Zhen Gu, 2014 A novel rapamycin-polymer conjugate based on a new poly(ethylene glycol) multiblock copolymer., Wanyi Tai, Zhijin Chen, Kun Cheng, 2014 Expression profile and functional activity of peptide transporters in prostate cancer cells., Wanyi Tai, Zhijin Chen, Kun Cheng, 2013 Development of a peptide-drug conjugate for prostate cancer therapy., Wanyi Tai, Ravi S. Shukla, Bin Qin, Benyi Li, Kun Cheng, 2011 Design, synthesis, and biological evaluation of ring‐opened bengamide analogues., Wan-Yi Tai#, Run-Tao Zhang#, Yi-Ming Ma, Min Gu, Gang Liu, Jia Li, Fa-Jun Nan, 2011 The role of HER2 in cancer therapy and targeted drug delivery., Wanyi Tai, Rubi Mahato, Kun Cheng, 2010 Inhibition of breast cancer cell growth and invasiveness by dual silencing of HER-2 and VEGF., Wanyi Tai, Bin Qin, Kun Cheng, 2010 Design, synthesis, and biological evaluation of caprolactam-modified bengamide analogues., Gang Liu#, Yi-Ming Ma#, Wan-Yi Tai#, Chuan-Ming Xie, Yu-Lin Li, Jia Li and Fa-Jun Nan, 2008

Areas of Focus

Pharmaceutics
Antibody Engineering
Biopharmaceutical Drug Delivery

Publications

Insight into the siRNA transmembrane delivery — from cholesterol conjugating to tagging., Yan Zheng, Wanyi Tai*, 2019
Current aspects of siRNA bioconjugate for in vitro and in vivo delivery., Wanyi Tai*, 2019
Chemical Modulation of siRNA lipophilicity for efficient delivery., Wanyi Tai*, 2019
Cytosolic delivery of proteins by cholesterol tagging., Wanyi Tai#, Pengfei Zhao#, Xiaohu Gao*, 2020
Silencing ribonucleoprotein: a biomimetic platform for targeted siRNA delivery., Wanyi Tai, Xiaohu Gao*, 2019
Synthetic polymer tag for intracellular delivery of siRNA., Wanyi Tai, Xiaohu Gao*, 2018
A ribonucleoprotein octamer for targeted siRNA delivery., Wanyi Tai, Junwei Li, Eva Corey, Xiaohu Gao*, 2018
Noncovalent tagging of siRNA with steroids for transmembrane delivery., Wanyi Tai, Xiaohu Gao*, 2018
Functional peptides for siRNA delivery., Wanyi Tai, Xiaohu Gao*, 2017
Bio-inspired nanovesicles for glucose-responsive release of insulin., Wanyi Tai, Ran Mo, Jin Di, Vinayak Subramanian, Xiao Gu, Zhen Gu*, 2014
Folding graft copolymer with pendant drug segment for co-delivery of anticancer drugs., Wanyi Tai#, Ran Mo#, Yue Lu, Tianyue Jiang, Zhen Gu*, 2014
A novel rapamycin-polymer conjugate based on a new poly(ethylene glycol) multiblock copolymer., Wanyi Tai, Zhijin Chen, Kun Cheng*, 2014
Expression profile and functional activity of peptide transporters in prostate cancer cells., Wanyi Tai, Zhijin Chen, Kun Cheng*, 2013
Development of a peptide-drug conjugate for prostate cancer therapy., Wanyi Tai, Ravi S. Shukla, Bin Qin, Benyi Li, Kun Cheng*, 2011
Design, synthesis, and biological evaluation of ring‐opened bengamide analogues., Wan-Yi Tai#, Run-Tao Zhang#, Yi-Ming Ma, Min Gu, Gang Liu, Jia Li, Fa-Jun Nan*, 2011
The role of HER2 in cancer therapy and targeted drug delivery., Wanyi Tai, Rubi Mahato, Kun Cheng*, 2010
Inhibition of breast cancer cell growth and invasiveness by dual silencing of HER-2 and VEGF., Wanyi Tai, Bin Qin, Kun Cheng*, 2010
Design, synthesis, and biological evaluation of caprolactam-modified bengamide analogues., Gang Liu#, Yi-Ming Ma#, Wan-Yi Tai#, Chuan-Ming Xie, Yu-Lin Li, Jia Li and Fa-Jun Nan*, 2008

Sirna Chemical Modification Delivery Lipophilicity Targeting Hydrophobicity Stability Biocompatibility Liposomes Exosomes

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