Professor | 台万一 | 数字化转型顾问

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Name	台万一
Contact Information	wanyi-tai@whu.edu.cn
Language ability	中文, 英语
Province	湖北省

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Name

台万一

Contact Information

wanyi-tai@whu.edu.cn

Language ability

中文, 英语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Medical School
Academic Background & Achievements	2000.09 - 2004.07 中国药科大学，中药药剂学学士 2004.09 - 2007.07 中国科学院上海药物研究所，药物化学硕士 2007.08 - 2012.08 美国密苏里大学堪萨斯城分校，药剂学博士
Work Experience	2012.09 - 2013.11 美国北卡罗来纳大学教堂山分校生物医学工程系，博士后 2013.12 - 2018.12 美国华盛顿大学生物工程系，博士后 2019.02 - 2020.11 武汉大学药学院，特聘研究员 2020.12 - 现在武汉大学药学院，教授

University/Lab Affiliation and Title

武汉大学

Faculty

Medical School

Academic Background & Achievements

2000.09 - 2004.07 中国药科大学，中药药剂学学士
2004.09 - 2007.07 中国科学院上海药物研究所，药物化学硕士
2007.08 - 2012.08 美国密苏里大学堪萨斯城分校，药剂学博士

Work Experience

2012.09 - 2013.11 美国北卡罗来纳大学教堂山分校生物医学工程系，博士后
2013.12 - 2018.12 美国华盛顿大学生物工程系，博士后
2019.02 - 2020.11 武汉大学药学院，特聘研究员
2020.12 - 现在武汉大学药学院，教授

Areas of Focus	药剂学抗体工程生物大分子药物递送
Publications	Insight into the siRNA transmembrane delivery — from cholesterol conjugating to tagging., Yan Zheng, Wanyi Tai, 2019 Current aspects of siRNA bioconjugate for in vitro and in vivo delivery., Wanyi Tai, 2019 Chemical Modulation of siRNA lipophilicity for efficient delivery., Wanyi Tai, 2019 Cytosolic delivery of proteins by cholesterol tagging., Wanyi Tai#, Pengfei Zhao#, Xiaohu Gao, 2020 Silencing ribonucleoprotein: a biomimetic platform for targeted siRNA delivery., Wanyi Tai, Xiaohu Gao, 2019 Synthetic polymer tag for intracellular delivery of siRNA., Wanyi Tai, Xiaohu Gao, 2018 A ribonucleoprotein octamer for targeted siRNA delivery., Wanyi Tai, Junwei Li, Eva Corey, Xiaohu Gao, 2018 Noncovalent tagging of siRNA with steroids for transmembrane delivery., Wanyi Tai, Xiaohu Gao, 2018 Functional peptides for siRNA delivery., Wanyi Tai, Xiaohu Gao, 2017 Bio-inspired nanovesicles for glucose-responsive release of insulin., Wanyi Tai, Ran Mo, Jin Di, Vinayak Subramanian, Xiao Gu, Zhen Gu, 2014 Folding graft copolymer with pendant drug segment for co-delivery of anticancer drugs., Wanyi Tai#, Ran Mo#, Yue Lu, Tianyue Jiang, Zhen Gu, 2014 A novel rapamycin-polymer conjugate based on a new poly(ethylene glycol) multiblock copolymer., Wanyi Tai, Zhijin Chen, Kun Cheng, 2014 Expression profile and functional activity of peptide transporters in prostate cancer cells., Wanyi Tai, Zhijin Chen, Kun Cheng, 2013 Development of a peptide-drug conjugate for prostate cancer therapy., Wanyi Tai, Ravi S. Shukla, Bin Qin, Benyi Li, Kun Cheng, 2011 Design, synthesis, and biological evaluation of ring‐opened bengamide analogues., Wan-Yi Tai#, Run-Tao Zhang#, Yi-Ming Ma, Min Gu, Gang Liu, Jia Li, Fa-Jun Nan, 2011 The role of HER2 in cancer therapy and targeted drug delivery., Wanyi Tai, Rubi Mahato, Kun Cheng, 2010 Inhibition of breast cancer cell growth and invasiveness by dual silencing of HER-2 and VEGF., Wanyi Tai, Bin Qin, Kun Cheng, 2010 Design, synthesis, and biological evaluation of caprolactam-modified bengamide analogues., Gang Liu#, Yi-Ming Ma#, Wan-Yi Tai#, Chuan-Ming Xie, Yu-Lin Li, Jia Li and Fa-Jun Nan, 2008

Areas of Focus

药剂学
抗体工程
生物大分子药物递送

Publications

Insight into the siRNA transmembrane delivery — from cholesterol conjugating to tagging., Yan Zheng, Wanyi Tai*, 2019
Current aspects of siRNA bioconjugate for in vitro and in vivo delivery., Wanyi Tai*, 2019
Chemical Modulation of siRNA lipophilicity for efficient delivery., Wanyi Tai*, 2019
Cytosolic delivery of proteins by cholesterol tagging., Wanyi Tai#, Pengfei Zhao#, Xiaohu Gao*, 2020
Silencing ribonucleoprotein: a biomimetic platform for targeted siRNA delivery., Wanyi Tai, Xiaohu Gao*, 2019
Synthetic polymer tag for intracellular delivery of siRNA., Wanyi Tai, Xiaohu Gao*, 2018
A ribonucleoprotein octamer for targeted siRNA delivery., Wanyi Tai, Junwei Li, Eva Corey, Xiaohu Gao*, 2018
Noncovalent tagging of siRNA with steroids for transmembrane delivery., Wanyi Tai, Xiaohu Gao*, 2018
Functional peptides for siRNA delivery., Wanyi Tai, Xiaohu Gao*, 2017
Bio-inspired nanovesicles for glucose-responsive release of insulin., Wanyi Tai, Ran Mo, Jin Di, Vinayak Subramanian, Xiao Gu, Zhen Gu*, 2014
Folding graft copolymer with pendant drug segment for co-delivery of anticancer drugs., Wanyi Tai#, Ran Mo#, Yue Lu, Tianyue Jiang, Zhen Gu*, 2014
A novel rapamycin-polymer conjugate based on a new poly(ethylene glycol) multiblock copolymer., Wanyi Tai, Zhijin Chen, Kun Cheng*, 2014
Expression profile and functional activity of peptide transporters in prostate cancer cells., Wanyi Tai, Zhijin Chen, Kun Cheng*, 2013
Development of a peptide-drug conjugate for prostate cancer therapy., Wanyi Tai, Ravi S. Shukla, Bin Qin, Benyi Li, Kun Cheng*, 2011
Design, synthesis, and biological evaluation of ring‐opened bengamide analogues., Wan-Yi Tai#, Run-Tao Zhang#, Yi-Ming Ma, Min Gu, Gang Liu, Jia Li, Fa-Jun Nan*, 2011
The role of HER2 in cancer therapy and targeted drug delivery., Wanyi Tai, Rubi Mahato, Kun Cheng*, 2010
Inhibition of breast cancer cell growth and invasiveness by dual silencing of HER-2 and VEGF., Wanyi Tai, Bin Qin, Kun Cheng*, 2010
Design, synthesis, and biological evaluation of caprolactam-modified bengamide analogues., Gang Liu#, Yi-Ming Ma#, Wan-Yi Tai#, Chuan-Ming Xie, Yu-Lin Li, Jia Li and Fa-Jun Nan*, 2008

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