Professor | Xiang Jin | Asia Growth Partners

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Name	Xiang Jin
Contact Information	xiangjin@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Xiang Jin

Contact Information

xiangjin@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2001-2006: PhD in Biochemistry and Molecular Biology, Wuhan University, Structural Biology Graduated with a PhD degree in 2006
Work Experience	2006-2016: Lecturer, School of Pharmaceutical Sciences, Wuhan University 2015-2016: Visiting Scholar, Arizona State University 2016-present: Associate Professor, School of Pharmaceutical Sciences, Wuhan University

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2001-2006: PhD in Biochemistry and Molecular Biology, Wuhan University, Structural Biology
Graduated with a PhD degree in 2006

Work Experience

2006-2016: Lecturer, School of Pharmaceutical Sciences, Wuhan University
2015-2016: Visiting Scholar, Arizona State University
2016-present: Associate Professor, School of Pharmaceutical Sciences, Wuhan University

Areas of Focus	Regulatory mechanisms of estrogen on cellular autophagy Discovery of new anticancer drugs based on structural basis and related molecular pharmacology Establishment of personalized cancer medication database
Publications	The effects of estrogen on targeted cancer therapy drugs, Zhao Y, Wang X, Liu Y, Wang HY, Xiang J, 2022 Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1, Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J, 2021 The Mechanism of Dehydrating Bimodules in trans-Acyltransferase Polyketide Biosynthesis: A Showcase Study on Hepatoprotective Hangtaimycin, Luo M, Xu H, Dong Y, Shen K, Lu J, Yin Z, Qi M, Sun G, Tang L, Xiang J, Deng Z, Dickschat JS, Sun Y, 2021 Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader, Zhao Y, Zhao C, Lu J, Wu J, Li C, Hu Z, Tian W, Yang L, Xiang J, Zhou H, Deng Z, Huang J, Hong K, 2019 How does estrogen work on autophagy?, Xiang J, Liu X, Ren J, Chen K, Wang HL, Miao YY, Qi MM, 2019 Successful Strategies to Determine High-Resolution Structures of GPCRs, Xiang J, Chun E, Liu C, Jing L, Al-Sahouri Z, Zhu L, Liu W, 2016 Ritonavir binds to and downregulates estrogen receptors: molecular mechanism of promoting early atherosclerosis, Xiang J, Wang Y, Su K, Liu M, Hu PC, Ma T, Li JX, Wei L, Zheng Z, Yang F, 2014 Matrine inhibits the adhesion and migration of BCG823 gastric cancer cells by affecting the structure and function of the vasodilator-stimulated phosphoprotein (VASP), Zhang JW, Su K, Shi WT, Wang Y, Hu PC, Wang Y, Wei L, Xiang J, Yang F, 2013 Interactions of newly designed dicationic carbazole derivatives with double-stranded DNA: syntheses, binding studies and AFM imaging, Jia T, Xiang J, Wang J, Guo P, Yu J, 2013 PrPC interacts with potassium channel tetramerization domain containing 1 (KCTD1) protein through the PrP(51-136) region containing octapeptide repeats, Huang T, Xu J, Xiang J, Lu Y, Chen R, Huang L, Xiao G, Sun G, 2012 Ritonavir stimulates foam cell formation by activating PKC, Xiang J, Sun G, Mu Y, Liu H, Liu Y, Yang F, Xu J, Ding H, 2011 Protective effects of glycyrrhizic acid by rectal treatment on a TNBS-induced rat colitis model, Liu Y, Xiang J, Liu M, Wang S, Lee RJ, Ding H, 2011 A disposable amperometric sensor for rapid detection of serotonin in the blood and brain of the depressed mice based on Nafion membrane-coated colloidal gold screen-printed electrode, Liu M, Xiang J, Zhou J, Ding H, 2010 Conformation-activity studies on the interaction of berberine with acetylcholinesterase: Physical chemistry approach, Xiang J, Yu C, Yang F, Yang L, Ding H, 2009 Interaction of cellulase with sodium dodecyl sulfate at critical micelle concentration level, Xiang J, Fan J-B, Chen N, Chen J, Liang Y, 2006

Areas of Focus

Regulatory mechanisms of estrogen on cellular autophagy
Discovery of new anticancer drugs based on structural basis and related molecular pharmacology
Establishment of personalized cancer medication database

Publications

The effects of estrogen on targeted cancer therapy drugs, Zhao Y, Wang X, Liu Y, Wang HY, Xiang J, 2022
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1, Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J, 2021
The Mechanism of Dehydrating Bimodules in trans-Acyltransferase Polyketide Biosynthesis: A Showcase Study on Hepatoprotective Hangtaimycin, Luo M, Xu H, Dong Y, Shen K, Lu J, Yin Z, Qi M, Sun G, Tang L, Xiang J, Deng Z, Dickschat JS, Sun Y, 2021
Sesterterpene MHO7 suppresses breast cancer cells as a novel estrogen receptor degrader, Zhao Y, Zhao C, Lu J, Wu J, Li C, Hu Z, Tian W, Yang L, Xiang J, Zhou H, Deng Z, Huang J, Hong K, 2019
How does estrogen work on autophagy?, Xiang J, Liu X, Ren J, Chen K, Wang HL, Miao YY, Qi MM, 2019
Successful Strategies to Determine High-Resolution Structures of GPCRs, Xiang J, Chun E, Liu C, Jing L, Al-Sahouri Z, Zhu L, Liu W, 2016
Ritonavir binds to and downregulates estrogen receptors: molecular mechanism of promoting early atherosclerosis, Xiang J, Wang Y, Su K, Liu M, Hu PC, Ma T, Li JX, Wei L, Zheng Z, Yang F, 2014
Matrine inhibits the adhesion and migration of BCG823 gastric cancer cells by affecting the structure and function of the vasodilator-stimulated phosphoprotein (VASP), Zhang JW, Su K, Shi WT, Wang Y, Hu PC, Wang Y, Wei L, Xiang J, Yang F, 2013
Interactions of newly designed dicationic carbazole derivatives with double-stranded DNA: syntheses, binding studies and AFM imaging, Jia T, Xiang J, Wang J, Guo P, Yu J, 2013
PrPC interacts with potassium channel tetramerization domain containing 1 (KCTD1) protein through the PrP(51-136) region containing octapeptide repeats, Huang T, Xu J, Xiang J, Lu Y, Chen R, Huang L, Xiao G, Sun G, 2012
Ritonavir stimulates foam cell formation by activating PKC, Xiang J, Sun G, Mu Y, Liu H, Liu Y, Yang F, Xu J, Ding H, 2011
Protective effects of glycyrrhizic acid by rectal treatment on a TNBS-induced rat colitis model, Liu Y, Xiang J, Liu M, Wang S, Lee RJ, Ding H, 2011
A disposable amperometric sensor for rapid detection of serotonin in the blood and brain of the depressed mice based on Nafion membrane-coated colloidal gold screen-printed electrode, Liu M, Xiang J, Zhou J, Ding H, 2010
Conformation-activity studies on the interaction of berberine with acetylcholinesterase: Physical chemistry approach, Xiang J, Yu C, Yang F, Yang L, Ding H, 2009
Interaction of cellulase with sodium dodecyl sulfate at critical micelle concentration level, Xiang J, Fan J-B, Chen N, Chen J, Liang Y, 2006

Estrogen Autophagy Cellular Effects Gper Receptor Cancer Prevention Therapeutic Strategies Molecular Pharmacology Drug Discovery Personalized Medicine Database Development

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