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Zhu Dongqing
Medical School
Wuhan University
Hubei
Language: Chinese, English
Molecular Genetics
Biochemistry
Combinatorial Biosynthesis
Natural Products
Gene Clusters
Pathway Exploration
Enzyme Catalysis
Molecular Level
Antibiotic Production
Metabolic Regulation
Areas of Focus
- Molecular genetics, biochemistry, and combinatorial biosynthesis of natural products
Work Experience
- 2008.9-2011.8 Postdoctoral Research Associate: Chemistry Department, Brown University
- 2011.9-present Associate Professor: School of Pharmaceutical Sciences, Wuhan University
Academic Background & Achievements
- 1998.9-2002.8 Bachelor in Biotechnology: Shandong University
- 2002.9-2008.8 PhD in Microbiology: Shanghai Jiao Tong University
Publications
- Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis, Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L, Deng Z, 2011
- Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone, Zhu D, Seo MJ, Ikeda H, Cane DE, 2011
- Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone, Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE, 2011
- Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an 'acyltransferase-less' type I polyketide synthase that incorporates two distinct extender units, Zhao C, Coughlin JM, Ju J, Zhu D, Wendt-Pienkowski E, Zhou X, Wang Z, Shen B, Deng Z, 2010
- Cloning of Antibiotic Biosynthetic Gene clusters from Genomic library by Narrow-down PCR, He Y, Zhu D, Bai L, Deng Z, 2009
- Positive Regulation of Avermectin Biosynthesis by AveR in Streptomyces avermitili, Zhu D, He Y, Bai L, Deng Z, 2008
- Expression of the melC operon in several Streptomyces strains is positively regulated by AdpA, an AraC family transcriptional regulator involved in morphological development in Streptomyces coelicolor, Zhu D, He X, Zhou X, Deng Z, 2005
- Study on xylose fermentation by Neurospora crassa, Zhang X, Zhu D, Wang D, Lin J, Qu Y, Yu S, 2003
- Production and Some Properties of Xylanase from Neurospora crassa, Zhang X, Zhu D, Wang D, Lin J, Qu Y, Yu S, 2002
