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Weichun Guo
Medical School
Wuhan University
Hubei
Language: Chinese, English
Spinal Surgery
Bone Tumors
Osteosarcoma
Bone Repair
Biomaterials
Surgical Techniques
Cancer Treatment
Regenerative Medicine
Clinical Research
Tissue Engineering
Areas of Focus
- Spinal surgery and bone tumors
- Biomaterials for bone regeneration
Work Experience
- 2004-2007: Attending Physician, Department of Spine Surgery, Renmin Hospital, Wuhan University
- 2007-2013: Deputy Chief Physician, Department of Spine Surgery, Renmin Hospital, Wuhan University
- 2008-Present: Associate Professor, Department of Spine Surgery, Renmin Hospital, Wuhan University
- 2013-Present: Chief Physician, Department of Spine Surgery, Renmin Hospital, Wuhan University
Academic Background & Achievements
- 1988-1994: Bachelor's Degree in Clinical Medicine from Hubei University of Science and Technology
- 1997-2000: Master's Degree from Tongji Medical College, Huazhong University of Science and Technology
- 2005-2008: PhD from Tongji Medical College, Huazhong University of Science and Technology
- Has led multiple research projects and received provincial awards
Publications
- TRIM26 inhibited osteosarcoma progression through destabilizing RACK1 and thus inactivation of MEK/ERK signaling, Xia KZ, Zheng D, Wei Z, Guo WC, 2023
- Carboxymethyl chitosan-alginate enhances bone repair effects of magnesium phosphate bone cement by activating the FAK-Wnt pathway, Yu L, Gao T, Li W, Yang J, Liu Y, Zhao Y, He P, Li X, Guo W, Fan Z, Dai H, 2022
- Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma, Zheng D, Wei Z, Guo W, 2022
- N6-Methyladenosine-Related lncRNAs Are Potential Prognostic Biomarkers and Correlated With Tumor Immune Microenvironment in Osteosarcoma, Zheng D, Yu L, Wei Z, Xia K, Guo W, 2022
- Comprehensive Analysis of a Zinc Finger Protein Gene-Based Signature with Regard to Prognosis and Tumor Immune Microenvironment in Osteosarcoma, Sun X, Zheng D, Guo W, 2022
- A Novel Six Metastasis-Related Prognostic Gene Signature for Patients With Osteosarcoma, Zheng D, Xia K, Yu L, Gong C, Shi Y, Li W, Qiu Y, Yang J, Guo W, 2021
- Enhancing the mechanical properties and cytocompatibility of magnesium potassium phosphate cement by incorporating oxygen-carboxymethyl chitosan, Gong C, Fang S, Xia K, Chen J, Guo L, Guo W, 2020
- FBXO2 modulates STAT3 signaling to regulate proliferation and tumorigenicity of osteosarcoma cells, Zhao X, Guo W, Zou L, Hu B, 2020
- LncRNA PLAC 2 Is Downregulated in Osteosarcoma and Regulates Cancer Cell Proliferation Through miR-93, Sun X, Yu L, Shi Y, Guo W, 2020
- An injectable bioactive magnesium phosphate cement incorporating carboxymethyl chitosan for bone regeneration, Yu L, Xia K, Gong C, Chen J, Li W, Zhao Y, Guo W, Dai H, 2020
- CDKN2B-AS1 Exerts Oncogenic Role in Osteosarcoma by Promoting Cell Proliferation and Epithelial to Mesenchymal Transition, Luo Y, Tao H, Jin L, Xiang W, Guo W, 2020
- Proscillaridin A induces apoptosis and inhibits the metastasis of osteosarcoma in vitro and in vivo, Fang S, Tao H, Xia K, Guo W, 2020
- The Notch Pathway Promotes Osteosarcoma Progression through Activation of Ephrin Reverse Signaling, Yu L, Xia K, Gao T, Chen J, Zhang Z, Sun X, Simões BM, Eyre R, Fan Z, Guo W, Clarke RB, 2019
- Synergistic effect of docetaxel combined with cisplatin on inhibiting human osteosarcoma in nude mice, Tao H, Tang X, Jin L, Zhao Y, Luo Y, Zhang Z, Cai L, Tao F, Guo W, 2018
- Notch pathway inhibition using DAPT, a γ-secretase inhibitor (GSI), enhances the antitumor effect of cisplatin in resistant osteosarcoma, Dai G, Deng S, Guo W, Yu L, Yang J, Zhou S, Gao T, 2019
Awards
- 2007: Third Prize of Natural Science of Hubei Province
- 2021: Second Prize of Hubei Science and Technology Progress Award (Principal Investigator)
