Professor | Zhiyong Wu | Asia Growth Partners

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Name	Zhiyong Wu
Contact Information	wzy2008@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Zhiyong Wu

Contact Information

wzy2008@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	1996.09-2001.06 Bachelor of Clinical Medicine: Zhangjiakou Medical College 2001.09-2004.06 Master of Surgery: Wuhan University First Clinical College 2006.09-2011.12 PhD in Surgery: Wuhan University First Clinical College Hosted and participated in multiple national and provincial research projects Received 5 provincial and ministerial science and technology awards
Work Experience	2004.07-2008.05 Wuhan University Renmin Hospital, Cardiovascular Surgery, Resident Physician 2008.05-2016.11 Wuhan University Renmin Hospital, Cardiovascular Surgery, Attending Physician 2014.03-2022.08 Wuhan University Renmin Hospital, Cardiovascular Surgery, Deputy Director 2016.11-2020.11 Wuhan University Renmin Hospital, Cardiovascular Surgery, Associate Chief Physician 2020.11-present Wuhan University Renmin Hospital, Cardiovascular Surgery, Chief Physician 2022.08-present Wuhan University Renmin Hospital, Cardiovascular Surgery, Director
Awards	2015 First Prize for Technological Progress in Hubei Province: Innovations in surgical techniques for complex ascending aortic dissection 2019 Second Prize for Scientific and Technological Achievement Promotion in Hubei Province: Clinical promotion and application of innovative surgical techniques for complex ascending aortic dissection

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

1996.09-2001.06 Bachelor of Clinical Medicine: Zhangjiakou Medical College
2001.09-2004.06 Master of Surgery: Wuhan University First Clinical College
2006.09-2011.12 PhD in Surgery: Wuhan University First Clinical College
Hosted and participated in multiple national and provincial research projects
Received 5 provincial and ministerial science and technology awards

Work Experience

2004.07-2008.05 Wuhan University Renmin Hospital, Cardiovascular Surgery, Resident Physician
2008.05-2016.11 Wuhan University Renmin Hospital, Cardiovascular Surgery, Attending Physician
2014.03-2022.08 Wuhan University Renmin Hospital, Cardiovascular Surgery, Deputy Director
2016.11-2020.11 Wuhan University Renmin Hospital, Cardiovascular Surgery, Associate Chief Physician
2020.11-present Wuhan University Renmin Hospital, Cardiovascular Surgery, Chief Physician
2022.08-present Wuhan University Renmin Hospital, Cardiovascular Surgery, Director

Awards

2015 First Prize for Technological Progress in Hubei Province: Innovations in surgical techniques for complex ascending aortic dissection
2019 Second Prize for Scientific and Technological Achievement Promotion in Hubei Province: Clinical promotion and application of innovative surgical techniques for complex ascending aortic dissection

Areas of Focus	Clinical and basic research of heart transplantation Minimally invasive treatment of cardiovascular disease
Publications	Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients, Zhiyong Wu, Rui Hu, Cuizhen Zhang, Wei Ren, Anfeng Yu, Xiaoyang Zhou, 2020 Obesity is a risk factor for preoperative hypoxemia in Stanford A acute aortic dissection, Zhiyong Wu, Wang Z, Wu H, Hu R, Ren W, Hu Z, Chang J, 2020 A Novel Finding: Macrophages Involved in Inflammation Participate in Acute Aortic Dissection Complicated with Acute Lung Injury, Zhiyong Wu, Wang Z, Xu P, Zhang M, Cheng L, Gong B, 2017 Bindarit reduces the incidence of acute aortic dissection complicated lung injury through modulating NF-κB pathway, Zhiyong Wu, Chang J, Ren W, Hu Z, Li B, Liu H, 2017 Interleukin 22 attenuated angiotensin II induced acute ling injury through inhibiting the apoptosis of pulmonary microvascular endothelial cells, Zhiyong Wu, Hu Z, Cai X, Ren W, Dai F, Liu H, Chang J, Li B, 2017 VE-cadherin involved in the pulmonary microvascular endothelial cell barrier injury induced by angiotensin II through modulating the cellular apoptosis and skeletal rearrangement, Zhiyong Wu, Liu H, Ren W, Dai F, Chang J, Li B, 2016 Dephosphorylation of Y685–VE- cadherin involved in pulmonary microvascular endothelial barrier injury induced by angiotensin II, Zhiyong Wu, Wang Z, Dai F, Liu H, Ren W, Chang J, Li B, 2016 Angiotensin II is related to the acute aortic dissection complicated with lung injury through mediating the release of MMP9 from macrophages, Zhiyong Wu, Ruan Y, Chang J, Li B, Ren W, 2016 Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte chemoattractant protein-1, Zhiyong Wu, Dai F, Ren W, Liu H, Li B, Chang J, 2016 Cyclic adenosine monophosphate protein kinase A signal pathway may be involved in pulmonary aquaporin-5 expression in ischemia/reperfusion rats following deep hypothermia cardiac arrest, Zhiyong Wu, Yao Y, Hu R, Dai FF, Zhang H, Mao ZF, 2016 Role of Nrf2 signal pathway in rats with deep hypothermia ischemia/reperfusion injury undergoing remote postconditioning, Zhiyong Wu, Wang ZW, Hu R, Zhou Z, Li LC, Mao ZF, 2015

Areas of Focus

Clinical and basic research of heart transplantation
Minimally invasive treatment of cardiovascular disease

Publications

Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients, Zhiyong Wu, Rui Hu, Cuizhen Zhang, Wei Ren, Anfeng Yu, Xiaoyang Zhou, 2020
Obesity is a risk factor for preoperative hypoxemia in Stanford A acute aortic dissection, Zhiyong Wu, Wang Z, Wu H, Hu R, Ren W, Hu Z, Chang J, 2020
A Novel Finding: Macrophages Involved in Inflammation Participate in Acute Aortic Dissection Complicated with Acute Lung Injury, Zhiyong Wu, Wang Z, Xu P, Zhang M, Cheng L, Gong B, 2017
Bindarit reduces the incidence of acute aortic dissection complicated lung injury through modulating NF-κB pathway, Zhiyong Wu, Chang J, Ren W, Hu Z, Li B, Liu H, 2017
Interleukin 22 attenuated angiotensin II induced acute ling injury through inhibiting the apoptosis of pulmonary microvascular endothelial cells, Zhiyong Wu, Hu Z, Cai X, Ren W, Dai F, Liu H, Chang J, Li B, 2017
VE-cadherin involved in the pulmonary microvascular endothelial cell barrier injury induced by angiotensin II through modulating the cellular apoptosis and skeletal rearrangement, Zhiyong Wu, Liu H, Ren W, Dai F, Chang J, Li B, 2016
Dephosphorylation of Y685–VE- cadherin involved in pulmonary microvascular endothelial barrier injury induced by angiotensin II, Zhiyong Wu, Wang Z, Dai F, Liu H, Ren W, Chang J, Li B, 2016
Angiotensin II is related to the acute aortic dissection complicated with lung injury through mediating the release of MMP9 from macrophages, Zhiyong Wu, Ruan Y, Chang J, Li B, Ren W, 2016
Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte chemoattractant protein-1, Zhiyong Wu, Dai F, Ren W, Liu H, Li B, Chang J, 2016
Cyclic adenosine monophosphate protein kinase A signal pathway may be involved in pulmonary aquaporin-5 expression in ischemia/reperfusion rats following deep hypothermia cardiac arrest, Zhiyong Wu, Yao Y, Hu R, Dai FF, Zhang H, Mao ZF, 2016
Role of Nrf2 signal pathway in rats with deep hypothermia ischemia/reperfusion injury undergoing remote postconditioning, Zhiyong Wu, Wang ZW, Hu R, Zhou Z, Li LC, Mao ZF, 2015

Heart Transplantation Clinical Research Basic Research Cardiovascular Minimally Invasive Surgery Treatment Heart Disease Transplant Surgery Medical Innovation

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