Professor | Mingchang Li | Asia Growth Partners

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Name	Mingchang Li
Contact Information	whulmc@126.com
Language ability	Chinese, English
Province	Hubei

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Name

Mingchang Li

Contact Information

whulmc@126.com

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	1991-1996 Bachelor of Clinical Medicine, Wuhan University 1998-2001 Master of Surgery, Tongji Medical College, Huazhong University of Science and Technology 2001-2004 PhD in Neurosurgery, Sun Yat-sen University Medical School Lead 4 national natural science foundation projects, published over 90 papers
Work Experience	1996-1998 Resident Surgeon, Xiaogan Central Hospital, Hubei 2004-2006 Attending Neurosurgeon, Second Affiliated Hospital of Guangzhou Medical University 2006-2012 Associate Chief Physician in Neurosurgery, Second Affiliated Hospital of Guangzhou Medical University 2012-2015 Chief Physician and Associate Professor in Neurosurgery, Renmin Hospital of Wuhan University 2015-present Chief Physician and Professor in Neurosurgery, Renmin Hospital of Wuhan University
Awards	2018 Wang Zhongcheng China Neurosurgery Physician Annual Youth Physician Award 2021 Second Prize, Hubei Province Science and Technology Progress Award for 'Molecular Mechanisms of Neuroprotection and Precision Treatment for Stroke'

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

1991-1996 Bachelor of Clinical Medicine, Wuhan University
1998-2001 Master of Surgery, Tongji Medical College, Huazhong University of Science and Technology
2001-2004 PhD in Neurosurgery, Sun Yat-sen University Medical School
Lead 4 national natural science foundation projects, published over 90 papers

Work Experience

1996-1998 Resident Surgeon, Xiaogan Central Hospital, Hubei
2004-2006 Attending Neurosurgeon, Second Affiliated Hospital of Guangzhou Medical University
2006-2012 Associate Chief Physician in Neurosurgery, Second Affiliated Hospital of Guangzhou Medical University
2012-2015 Chief Physician and Associate Professor in Neurosurgery, Renmin Hospital of Wuhan University
2015-present Chief Physician and Professor in Neurosurgery, Renmin Hospital of Wuhan University

Awards

2018 Wang Zhongcheng China Neurosurgery Physician Annual Youth Physician Award
2021 Second Prize, Hubei Province Science and Technology Progress Award for 'Molecular Mechanisms of Neuroprotection and Precision Treatment for Stroke'

Areas of Focus	Microsurgery and interventional treatment of various complex cerebrovascular diseases Neuroprotection in hemorrhagic transformation of cerebral infarction Clinical and basic research on hemorrhagic cerebrovascular diseases
Publications	Netrin-1 Alleviates Early Brain Injury by Regulating Ferroptosis via the PPARγ/Nrf2/GPX4 Signaling Pathway Following Subarachnoid Hemorrhage, Chen J, Wang Y, Li M, Zhu X, Liu Z, Chen Q, Xiong K, 2023 Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke, Wang J, He P, Tian Q, Luo Y, He Y, Liu C, Gong P, Guo Y, Ye Q, Li M, 2023 Histone tyrosine sulfation by SULT1B1 regulates H4R3me2a and gene transcription, Yu W, Zhou R, Li N, Lei ZC, Guo D, Peng F, Li Y, Bai X, Feng S, Wang Y, He J, Yin S, Zeng X, He L, Gao Y, Li M, Guo YR, Liu K, Wang Y, 2023 The mechanism and relevant mediators associated with neuronal apoptosis and potential therapeutic targets in subarachnoid hemorrhage, Tian Q, Liu S, Han SM, Zhang W, Qin XY, Chen JH, Liu CL, Guo YJ, Li MC, 2023 Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways, Liu C, Tian Q, Wang J, He P, Han S, Guo Y, Yang C, Wang G, Wei H, Li M, 2023 MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases, Zhou H, He Y, Xiong W, Jing S, Duan X, Huang Z, Nahal GS, Peng Y, Li M, Zhu Y, Ye Q, 2022 Taurine attenuates neuronal ferroptosis by regulating GABAB/AKT/GSK3β/β-catenin pathway after subarachnoid hemorrhage, Liu C, He P, Guo Y, Tian Q, Wang J, Wang G, Zhang Z, Li M, 2022 Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway, Tian Q, Guo Y, Feng S, Liu C, He P, Wang J, Han W, Yang C, Zhang Z, Li M, 2022 Molecular mechanisms of neuronal death in brain injury after subarachnoid hemorrhage, Chen J, Li M, Liu Z, Wang Y, Xiong K, 2022 Dental pulp stem cell transplantation facilitates neuronal neuroprotection following cerebral ischemic stroke, Gong P, Tian Q, He Y, He P, Wang J, Guo Y, Ye Q, Li M, 2022 Diabetes or calcium channel blocker contribute to cerebral hemodynamics after bypass surgery in adult patients with moyamoya disease, Han S, Cai L, Tian Q, Wei H, Wang G, Wang J, He P, Liao J, Zhang S, Chen Q, Li M, 2023 A web-based dynamic nomogram for rupture risk of posterior communicating artery aneurysms utilizing clinical, morphological, and hemodynamic characteristics, Wei H, Han W, Tian Q, Yao K, He P, Wang J, Guo Y, Chen Q, Li M, 2022 Andrographolide Attenuates Blood-Brain Barrier Disruption, Neuronal Apoptosis, and Oxidative Stress Through Activation of Nrf2/HO-1 Signaling Pathway in Subarachnoid Hemorrhage, Gong P, Zhang W, Zou C, Han S, Tian Q, Wang J, He P, Guo Y, Li M, 2022 Different Hemodynamic Characteristics and Resulting in Different Risks of Rupture Between Wide-Neck and Narrow-Neck Aneurysms, Wei H, Tian Q, Yao K, Wang J, He P, Guo Y, Han W, Gao W, Li M, 2022 The eIF4A Inhibitor Silvestrol Blocks the Growth of Human Glioblastoma Cells by Inhibiting AKT/mTOR and ERK1/2 Signaling Pathway, Zhang W, Gong P, Tian Q, Han S, Wang J, He P, Guo Y, Wang G, Chen Q, Huang J, Li M, 2022 Efficacy and safety of embolization for arteriovenous malformations of the basal ganglia and thalamus via the transarterial approach, Zhang W, Heng Wei, Qi Tian, Shoumeng Han, Wenrui Han, Yujia Guo, Guijun Wang, Shenqi Zhang, Gang Deng, Junming Wang, Qianxue Chen, Li M, 2022

Areas of Focus

Microsurgery and interventional treatment of various complex cerebrovascular diseases
Neuroprotection in hemorrhagic transformation of cerebral infarction
Clinical and basic research on hemorrhagic cerebrovascular diseases

Publications

Netrin-1 Alleviates Early Brain Injury by Regulating Ferroptosis via the PPARγ/Nrf2/GPX4 Signaling Pathway Following Subarachnoid Hemorrhage, Chen J, Wang Y, Li M, Zhu X, Liu Z, Chen Q, Xiong K, 2023
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke, Wang J, He P, Tian Q, Luo Y, He Y, Liu C, Gong P, Guo Y, Ye Q, Li M, 2023
Histone tyrosine sulfation by SULT1B1 regulates H4R3me2a and gene transcription, Yu W, Zhou R, Li N, Lei ZC, Guo D, Peng F, Li Y, Bai X, Feng S, Wang Y, He J, Yin S, Zeng X, He L, Gao Y, Li M, Guo YR, Liu K, Wang Y, 2023
The mechanism and relevant mediators associated with neuronal apoptosis and potential therapeutic targets in subarachnoid hemorrhage, Tian Q, Liu S, Han SM, Zhang W, Qin XY, Chen JH, Liu CL, Guo YJ, Li MC, 2023
Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways, Liu C, Tian Q, Wang J, He P, Han S, Guo Y, Yang C, Wang G, Wei H, Li M, 2023
MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases, Zhou H, He Y, Xiong W, Jing S, Duan X, Huang Z, Nahal GS, Peng Y, Li M, Zhu Y, Ye Q, 2022
Taurine attenuates neuronal ferroptosis by regulating GABAB/AKT/GSK3β/β-catenin pathway after subarachnoid hemorrhage, Liu C, He P, Guo Y, Tian Q, Wang J, Wang G, Zhang Z, Li M, 2022
Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway, Tian Q, Guo Y, Feng S, Liu C, He P, Wang J, Han W, Yang C, Zhang Z, Li M, 2022
Molecular mechanisms of neuronal death in brain injury after subarachnoid hemorrhage, Chen J, Li M, Liu Z, Wang Y, Xiong K, 2022
Dental pulp stem cell transplantation facilitates neuronal neuroprotection following cerebral ischemic stroke, Gong P, Tian Q, He Y, He P, Wang J, Guo Y, Ye Q, Li M, 2022
Diabetes or calcium channel blocker contribute to cerebral hemodynamics after bypass surgery in adult patients with moyamoya disease, Han S, Cai L, Tian Q, Wei H, Wang G, Wang J, He P, Liao J, Zhang S, Chen Q, Li M, 2023
A web-based dynamic nomogram for rupture risk of posterior communicating artery aneurysms utilizing clinical, morphological, and hemodynamic characteristics, Wei H, Han W, Tian Q, Yao K, He P, Wang J, Guo Y, Chen Q, Li M, 2022
Andrographolide Attenuates Blood-Brain Barrier Disruption, Neuronal Apoptosis, and Oxidative Stress Through Activation of Nrf2/HO-1 Signaling Pathway in Subarachnoid Hemorrhage, Gong P, Zhang W, Zou C, Han S, Tian Q, Wang J, He P, Guo Y, Li M, 2022
Different Hemodynamic Characteristics and Resulting in Different Risks of Rupture Between Wide-Neck and Narrow-Neck Aneurysms, Wei H, Tian Q, Yao K, Wang J, He P, Guo Y, Han W, Gao W, Li M, 2022
The eIF4A Inhibitor Silvestrol Blocks the Growth of Human Glioblastoma Cells by Inhibiting AKT/mTOR and ERK1/2 Signaling Pathway, Zhang W, Gong P, Tian Q, Han S, Wang J, He P, Guo Y, Wang G, Chen Q, Huang J, Li M, 2022
Efficacy and safety of embolization for arteriovenous malformations of the basal ganglia and thalamus via the transarterial approach, Zhang W, Heng Wei, Qi Tian, Shoumeng Han, Wenrui Han, Yujia Guo, Guijun Wang, Shenqi Zhang, Gang Deng, Junming Wang, Qianxue Chen, Li M, 2022

Microsurgery Interventional Treatment Cerebrovascular Diseases Neuroprotection Hemorrhagic Transformation Cerebral Infarction Clinical Research Basic Research Hemorrhagic Cerebrovascular Stroke

Yihui Ma - Wuhan University

Xianlong Zhou - Wuhan University

Jing Chen - Wuhan University

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