Areas of Focus
- Research on the mechanisms of HBV virology and viral hepatitis
- Development of new active immunization and delivery strategies to eliminate persistent HBV infection
- Research and development of antiviral drugs for COVID-19
Work Experience
- 2005.05—2008.10 - Pasteur Institute, Paris - Postdoctoral Researcher
- 2008.11—2016.12 - Shanghai Pasteur Institute, Chinese Academy of Sciences - Associate Researcher, Researcher
- 2017.01—Present - Fudan University, School of Basic Medical Sciences - Researcher
Academic Background & Achievements
- 1997.09—2000.09 Master's Degree: China Pharmaceutical University, School of Pharmacy
- 2000.09—2004.07 Doctoral Degree: Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Publications
- Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection., Yuan S, Liao G, Zhang M, Zhu Y, Wang K, Xiao W, Jia C, Dong M, Sun N, Walch A, Xu P, Zhang J, Deng Q, Hu R., 2021
- Recombinant covalently closed circular DNA of hepatitis B virus induces long-term viral persistence with chronic hepatitis in a mouse model., Li G, Zhu Y, Shao D, Chang H, Zhang X, Zhou D, Gao Y, Lan K, Deng Q., 2018
- Hepatitis B core protein sensitizes hepatocytes to tumor necrosis factor-induced apoptosis by suppression of the phosphorylation of mitogen-activated protein kinase kinase 7., Jia B, Guo M, Li G, Yu D, Zhang X, Lan K, Deng Q., 2015
- Recombinant covalently closed circular hepatitis B virus DNA induces prolonged viral persistence in immunocompetent mice., Qi Z, Li G, Hu H, Yang C, Zhang X, Leng Q, Xie Y, Yu D, Zhang X, Gao Y, Lan K, Deng Q., 2014
- Adenoviral delivery of recombinant hepatitis B virus expressing foreign antigenic epitopes for immunotherapy of persistent viral infection., Wang Z, Zhu K, Bai W, Jia B, Hu H, Zhou D, Zhang X, Zhang X, Xie Y, Bourgine MM, Michel ML, Lan K, Deng Q., 2014
Awards
- Sanofi-Aventis Outstanding Young Talent Award (2010): Shanghai Institute of Life Sciences, Chinese Academy of Sciences
- Lu Jiaxi Young Talent Award (2010): Chinese Academy of Sciences