Professor | Kuanhui Xiang | Asia Growth Partners

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Name	Kuanhui Xiang
Contact Information	kxiang@bjmu.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Kuanhui Xiang

Contact Information

kxiang@bjmu.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2011.09-2017.07 PhD in Pathogen Biology: Peking University 2006.09-2011.07 Bachelor in Medical Testing: Hebei Medical University
Work Experience	2022.08-present Peking University, Pathogen Biology, Associate Research Fellow 2017.08-2022.07 Peking University, Pathogen Biology, Lecturer 2014.09-2016.08 Rockefeller University, Charles M. Rice Laboratory, Joint Training
Awards	2022 Peking University Outstanding Teaching Achievement First Prize (2/11) 2021 Chinese Medical Science and Technology Award Second Prize (5/15) 2021 Peking University Young Talent 2020 Basic Medical College Young Teacher Award Fund 2019/2018 International HBV Meeting Travel Award 2019 Outstanding Paper Citation Award

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2011.09-2017.07 PhD in Pathogen Biology: Peking University
2006.09-2011.07 Bachelor in Medical Testing: Hebei Medical University

Work Experience

2022.08-present Peking University, Pathogen Biology, Associate Research Fellow
2017.08-2022.07 Peking University, Pathogen Biology, Lecturer
2014.09-2016.08 Rockefeller University, Charles M. Rice Laboratory, Joint Training

Awards

2022 Peking University Outstanding Teaching Achievement First Prize (2/11)
2021 Chinese Medical Science and Technology Award Second Prize (5/15)
2021 Peking University Young Talent
2020 Basic Medical College Young Teacher Award Fund
2019/2018 International HBV Meeting Travel Award
2019 Outstanding Paper Citation Award

Areas of Focus	Establishment and optimization of viral infection and pathogenesis models Mechanisms of virus-host interactions
Publications	Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA, Kuanhui Xiang, Eleftherios Michailidis, Hai Ding, Ya-Qin Peng, Ming-Ze Su, Yao Li, Xue-En Liu, Viet Loan Dao Thi, Xian-Fang Wu, William M Schneider, Charles M Rice, Hui Zhuang, Tong Li , 2017 The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro, Huahao Fan, Bixia Hong, Yuqian Luo, Qi Peng, Liqin Wang, Xiangshu Jin, Yangzhen Chen, Yunjia Hu, Yi Shi, Tong Li, Hui Zhuang, Yi-Hua Zhou, Yigang Tong, Kuanhui Xiang, 2020 Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro, Xinyuan Lai, Chuanyun Li, Chengang Xian, Zihang Pan, Kai Zhang, Lei Wang, Bingqing Xie, Junning Cao, Jihang Shi, Juan Deng, Shichun Lu, Hongkui Deng, Hui Zhuang, Tong Li1, Yan Shi3, Kuanhui Xiang, 2022 A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection, Kai Zhang, Xinyuan Lai, Ji Song, Lingyuan He, Luwei Wang, Guomin Ou, Xing Tian, Lei Wang, Juan Deng, Jiajia Zhang, Chuanyun Li, Hui Zhuang, Tong Li, Kuanhui Xiang, 2021 TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity, Xing Tian, Huijun Dong, Xinyuan Lai, Guomin Ou, Junning Cao, Jihang Shi, Chengang Xiang, Lei Wang, Xuechao Zhang, Kai Zhang, Ji Song, Juan Deng, Hongkui Deng, Shichun Lu, Hui Zhuang, Tong Li, Kuanhui Xiang, 2022 Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication, Xinyuan Lai, Yanying Yu, Wei Xian, Fei Ye, Xiaohui Ju, Yuqian Luo, Huijun Dong, Yi-Hua Zhou, Wenjie Tan, Hui Zhuang, Tong Li, Xiaoyun Liu, Qiang Ding, Kuanhui Xiang, 2022 Inhibition of In Vitro Infection of Hepatitis B Virus by Human Breastmilk, Yuqian Luo, Kuanhui Xiang, Jingli Liu, Ji Song, Jing Feng, Jie Chen, Yimin Dai, Yali Hu, Hui Zhuang, Yihua Zhou, 2022 Long-term functional maintenance of primary human hepatocytes in vitro, Chengang Xiang, Yuanyuan Du, Gaofan Meng, Liew Soon Yi, Shicheng Sun, Nan Song, Xiaonan Zhang, Yiwei Xiao, Jie Wang, Zhigang Yi, Yifang Liu, Bingqing Xie, Min Wu, Jun Shu, Da Sun, Jun Jia, Zhen Liang, Dong Sun, Yanxiang Huang, Yan Shi, Jun Xu, Fengmin Lu, Cheng Li, Kuanhui Xiang, Zhenghong Yuan, Shichun Lu, Hongkui Deng, 2019 Pan-Genotype Hepatitis E Virus Replication in Stem Cell-Derived Hepatocellular Systems, Xianfang Wu, Viet Loan Dao Thi, Peng Liu, Constantin N Takacs, Kuanhui Xiang, Linda Andrus, Jérôme Gouttenoire, Darius Moradpour, Charles M Rice, 2018 A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts, Bingqing Xie, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu, Yifang Liu, Chengang Xiang, Sitong Chen, Huangfan Xie, Qiming Wang, Guangya Li, Xuehui Lyu, Hui Shen, Shiyu Li, Min Wu, Xiaonan Zhang, Yue Pu, Kuanhui Xiang, Weifeng Lai, Peng Du, Zhenghong Yuan, Cheng Li, Yan Shi, Shichun Lu, Hongkui Deng*, 2019

Areas of Focus

Establishment and optimization of viral infection and pathogenesis models
Mechanisms of virus-host interactions

Publications

Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA, Kuanhui Xiang, Eleftherios Michailidis, Hai Ding, Ya-Qin Peng, Ming-Ze Su, Yao Li, Xue-En Liu, Viet Loan Dao Thi, Xian-Fang Wu, William M Schneider, Charles M Rice, Hui Zhuang*, Tong Li *, 2017
The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro, Huahao Fan, Bixia Hong, Yuqian Luo, Qi Peng, Liqin Wang, Xiangshu Jin, Yangzhen Chen, Yunjia Hu, Yi Shi, Tong Li, Hui Zhuang, Yi-Hua Zhou*, Yigang Tong*, Kuanhui Xiang*, 2020
Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro, Xinyuan Lai, Chuanyun Li, Chengang Xian, Zihang Pan, Kai Zhang, Lei Wang, Bingqing Xie, Junning Cao, Jihang Shi, Juan Deng, Shichun Lu, Hongkui Deng, Hui Zhuang, Tong Li1*, Yan Shi3*, Kuanhui Xiang*, 2022
A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection, Kai Zhang, Xinyuan Lai, Ji Song, Lingyuan He, Luwei Wang, Guomin Ou, Xing Tian, Lei Wang, Juan Deng, Jiajia Zhang, Chuanyun Li, Hui Zhuang*, Tong Li*, Kuanhui Xiang*, 2021
TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity, Xing Tian, Huijun Dong, Xinyuan Lai, Guomin Ou, Junning Cao, Jihang Shi, Chengang Xiang, Lei Wang, Xuechao Zhang, Kai Zhang, Ji Song, Juan Deng, Hongkui Deng, Shichun Lu, Hui Zhuang*, Tong Li*, Kuanhui Xiang*, 2022
Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication, Xinyuan Lai, Yanying Yu, Wei Xian, Fei Ye, Xiaohui Ju, Yuqian Luo, Huijun Dong, Yi-Hua Zhou, Wenjie Tan, Hui Zhuang, Tong Li, Xiaoyun Liu*, Qiang Ding*, Kuanhui Xiang*, 2022
Inhibition of In Vitro Infection of Hepatitis B Virus by Human Breastmilk, Yuqian Luo, Kuanhui Xiang, Jingli Liu, Ji Song, Jing Feng, Jie Chen, Yimin Dai, Yali Hu, Hui Zhuang*, Yihua Zhou*, 2022
Long-term functional maintenance of primary human hepatocytes in vitro, Chengang Xiang, Yuanyuan Du, Gaofan Meng, Liew Soon Yi, Shicheng Sun, Nan Song, Xiaonan Zhang, Yiwei Xiao, Jie Wang, Zhigang Yi, Yifang Liu, Bingqing Xie, Min Wu, Jun Shu, Da Sun, Jun Jia, Zhen Liang, Dong Sun, Yanxiang Huang, Yan Shi, Jun Xu, Fengmin Lu, Cheng Li, Kuanhui Xiang, Zhenghong Yuan*, Shichun Lu*, Hongkui Deng*, 2019
Pan-Genotype Hepatitis E Virus Replication in Stem Cell-Derived Hepatocellular Systems, Xianfang Wu, Viet Loan Dao Thi, Peng Liu, Constantin N Takacs, Kuanhui Xiang, Linda Andrus, Jérôme Gouttenoire, Darius Moradpour, Charles M Rice, 2018
A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts, Bingqing Xie, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu, Yifang Liu, Chengang Xiang, Sitong Chen, Huangfan Xie, Qiming Wang, Guangya Li, Xuehui Lyu, Hui Shen, Shiyu Li, Min Wu, Xiaonan Zhang, Yue Pu, Kuanhui Xiang, Weifeng Lai, Peng Du, Zhenghong Yuan, Cheng Li, Yan Shi*, Shichun Lu*, Hongkui Deng*, 2019

Viral Infection Pathogenesis Models Virus-Host Interactions Hbv Sars-Cov-2 Antiviral Drugs Viral Replication Viral Mutation Immune Response Therapeutic Targets

Wei Hou - Wuhan University

Hai-Rong Xiong - Wuhan University

Qiang Deng - Fudan University

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