Professor | 向宽辉 | 数字化转型顾问

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Name	向宽辉
Contact Information	kxiang@bjmu.edu.cn
Language ability	中文, 英语
Province	北京

Upload Avatar (500 x 500)

Name

向宽辉

Contact Information

kxiang@bjmu.edu.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	北京大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2011.09-2017.07 北京大学，病原生物学，博士 2006.09-2011.07 河北医科大学，医学检验，学士
Work Experience	2022.08-目前北京大学，病原生物学，副研究员 2017.08-2022.07 北京大学，病原生物学，讲师 2014.09-2016.08 美国洛克菲勒大学，诺奖获得者Charles M. Rice实验室，联合培养
Awards	2022年，北京大学优秀教学成果一等奖（2/11） 2021年，中华医学科技奖二等奖（5/15） 2021年，北京大学青年岗位能手 2020年，基础医学院青年教师奖励基金 2019/2018年，国际HBV大会Travel Award 2019年，优秀论文引用奖

University/Lab Affiliation and Title

北京大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2011.09-2017.07 北京大学，病原生物学，博士
2006.09-2011.07 河北医科大学，医学检验，学士

Work Experience

2022.08-目前北京大学，病原生物学，副研究员
2017.08-2022.07 北京大学，病原生物学，讲师
2014.09-2016.08 美国洛克菲勒大学，诺奖获得者Charles M. Rice实验室，联合培养

Awards

2022年，北京大学优秀教学成果一等奖（2/11）
2021年，中华医学科技奖二等奖（5/15）
2021年，北京大学青年岗位能手
2020年，基础医学院青年教师奖励基金
2019/2018年，国际HBV大会Travel Award
2019年，优秀论文引用奖

Areas of Focus	病毒感染和致病模型的建立与优化病毒与宿主相互作用的机制研究
Publications	Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA, 向宽辉, Eleftherios Michailidis, Hai Ding, Ya-Qin Peng, Ming-Ze Su, Yao Li, Xue-En Liu, Viet Loan Dao Thi, Xian-Fang Wu, William M Schneider, Charles M Rice, Hui Zhuang, Tong Li , 2017 The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro, Huahao Fan, Bixia Hong, Yuqian Luo, Qi Peng, Liqin Wang, Xiangshu Jin, Yangzhen Chen, Yunjia Hu, Yi Shi, Tong Li, Hui Zhuang, Yi-Hua Zhou, Yigang Tong, 向宽辉, 2020 Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro, Xinyuan Lai, Chuanyun Li, Chengang Xian, Zihang Pan, Kai Zhang, Lei Wang, Bingqing Xie, Junning Cao, Jihang Shi, Juan Deng, Shichun Lu, Hongkui Deng, Hui Zhuang, Tong Li1, Yan Shi3, 向宽辉, 2022 A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection, Kai Zhang, Xinyuan Lai, Ji Song, Lingyuan He, Luwei Wang, Guomin Ou, Xing Tian, Lei Wang, Juan Deng, Jiajia Zhang, Chuanyun Li, Hui Zhuang, Tong Li, 向宽辉, 2021 TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity, Xing Tian, Huijun Dong, Xinyuan Lai, Guomin Ou, Junning Cao, Jihang Shi, Chengang Xiang, Lei Wang, Xuechao Zhang, Kai Zhang, Ji Song, Juan Deng, Hongkui Deng, Shichun Lu, Hui Zhuang, Tong Li, 向宽辉, 2022 Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication, Xinyuan Lai, Yanying Yu, Wei Xian, Fei Ye, Xiaohui Ju, Yuqian Luo, Huijun Dong, Yi-Hua Zhou, Wenjie Tan, Hui Zhuang, Tong Li, Xiaoyun Liu, Qiang Ding, 向宽辉, 2022 Inhibition of In Vitro Infection of Hepatitis B Virus by Human Breastmilk, Yuqian Luo, 向宽辉, Jingli Liu, Ji Song, Jing Feng, Jie Chen, Yimin Dai, Yali Hu, Hui Zhuang, Yihua Zhou, 2022 Long-term functional maintenance of primary human hepatocytes in vitro, Chengang Xiang, Yuanyuan Du, Gaofan Meng, Liew Soon Yi, Shicheng Sun, Nan Song, Xiaonan Zhang, Yiwei Xiao, Jie Wang, Zhigang Yi, Yifang Liu, Bingqing Xie, Min Wu, Jun Shu, Da Sun, Jun Jia, Zhen Liang, Dong Sun, Yanxiang Huang, Yan Shi, Jun Xu, Fengmin Lu, Cheng Li, 向宽辉, Zhenghong Yuan, Shichun Lu, Hongkui Deng, 2019 Pan-Genotype Hepatitis E Virus Replication in Stem Cell-Derived Hepatocellular Systems, Xianfang Wu, Viet Loan Dao Thi, Peng Liu, Constantin N Takacs, 向宽辉, Linda Andrus, Jérôme Gouttenoire, Darius Moradpour, Charles M Rice, 2018 A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts, Bingqing Xie, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu, Yifang Liu, Chengang Xiang, Sitong Chen, Huangfan Xie, Qiming Wang, Guangya Li, Xuehui Lyu, Hui Shen, Shiyu Li, Min Wu, Xiaonan Zhang, Yue Pu, 向宽辉, Weifeng Lai, Peng Du, Zhenghong Yuan, Cheng Li, Yan Shi, Shichun Lu, Hongkui Deng*, 2019

Areas of Focus

病毒感染和致病模型的建立与优化
病毒与宿主相互作用的机制研究

Publications

Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA, 向宽辉, Eleftherios Michailidis, Hai Ding, Ya-Qin Peng, Ming-Ze Su, Yao Li, Xue-En Liu, Viet Loan Dao Thi, Xian-Fang Wu, William M Schneider, Charles M Rice, Hui Zhuang*, Tong Li *, 2017
The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro, Huahao Fan, Bixia Hong, Yuqian Luo, Qi Peng, Liqin Wang, Xiangshu Jin, Yangzhen Chen, Yunjia Hu, Yi Shi, Tong Li, Hui Zhuang, Yi-Hua Zhou*, Yigang Tong*, 向宽辉*, 2020
Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro, Xinyuan Lai, Chuanyun Li, Chengang Xian, Zihang Pan, Kai Zhang, Lei Wang, Bingqing Xie, Junning Cao, Jihang Shi, Juan Deng, Shichun Lu, Hongkui Deng, Hui Zhuang, Tong Li1*, Yan Shi3*, 向宽辉*, 2022
A novel cell culture model reveals the viral interference during hepatitis B and C virus coinfection, Kai Zhang, Xinyuan Lai, Ji Song, Lingyuan He, Luwei Wang, Guomin Ou, Xing Tian, Lei Wang, Juan Deng, Jiajia Zhang, Chuanyun Li, Hui Zhuang*, Tong Li*, 向宽辉*, 2021
TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity, Xing Tian, Huijun Dong, Xinyuan Lai, Guomin Ou, Junning Cao, Jihang Shi, Chengang Xiang, Lei Wang, Xuechao Zhang, Kai Zhang, Ji Song, Juan Deng, Hongkui Deng, Shichun Lu, Hui Zhuang*, Tong Li*, 向宽辉*, 2022
Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication, Xinyuan Lai, Yanying Yu, Wei Xian, Fei Ye, Xiaohui Ju, Yuqian Luo, Huijun Dong, Yi-Hua Zhou, Wenjie Tan, Hui Zhuang, Tong Li, Xiaoyun Liu*, Qiang Ding*, 向宽辉*, 2022
Inhibition of In Vitro Infection of Hepatitis B Virus by Human Breastmilk, Yuqian Luo, 向宽辉, Jingli Liu, Ji Song, Jing Feng, Jie Chen, Yimin Dai, Yali Hu, Hui Zhuang*, Yihua Zhou*, 2022
Long-term functional maintenance of primary human hepatocytes in vitro, Chengang Xiang, Yuanyuan Du, Gaofan Meng, Liew Soon Yi, Shicheng Sun, Nan Song, Xiaonan Zhang, Yiwei Xiao, Jie Wang, Zhigang Yi, Yifang Liu, Bingqing Xie, Min Wu, Jun Shu, Da Sun, Jun Jia, Zhen Liang, Dong Sun, Yanxiang Huang, Yan Shi, Jun Xu, Fengmin Lu, Cheng Li, 向宽辉, Zhenghong Yuan*, Shichun Lu*, Hongkui Deng*, 2019
Pan-Genotype Hepatitis E Virus Replication in Stem Cell-Derived Hepatocellular Systems, Xianfang Wu, Viet Loan Dao Thi, Peng Liu, Constantin N Takacs, 向宽辉, Linda Andrus, Jérôme Gouttenoire, Darius Moradpour, Charles M Rice, 2018
A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts, Bingqing Xie, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu, Yifang Liu, Chengang Xiang, Sitong Chen, Huangfan Xie, Qiming Wang, Guangya Li, Xuehui Lyu, Hui Shen, Shiyu Li, Min Wu, Xiaonan Zhang, Yue Pu, 向宽辉, Weifeng Lai, Peng Du, Zhenghong Yuan, Cheng Li, Yan Shi*, Shichun Lu*, Hongkui Deng*, 2019

病毒感染致病模型病毒宿主互作 Hbv Sars-Cov-2 抗病毒药物病毒复制病毒变异免疫反应治疗靶点

鲁凤民 - 北京大学

王杰 - 北京大学

李彤 - 北京大学

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